任刚，遗传学博士（理学），博导、教授

2021年-至今：西北农林科技大学高层次引进人才  动物科技学院教授、博导

2016年-2021年：美国国立卫生研究院 博士后研究 (获美国国立卫生研究院 Fellow Award资助)

2009-2015年：西北农林科技大学---美国国家健康研究院联合培养博士研究生  遗传学（获美国国立卫生研究院 GPP奖学金）

任刚博士长期从事表观遗传学及其调控机理的研究。主要开发和应用基因组学、三维基因组学、表观遗传组学，以及单细胞测序技术等解析家畜动物早期胚胎，以及肌肉组织相关的细胞分化、发育、以及命运决定过程中的调控机理和生产应用。

目前主要研究方向：

1. 染色质高级结构的动态变化规律及调控机制

2. 细胞命运决定过程中的表观遗传调控机理

3.家畜抗病生物育种，家畜生产性状/抗病/抗逆的表观遗传调控

Selected Publications: (*Corresponding Author, #Co-first author)

1.G Ren#, WL Ku#, GZ Ge#, JA Hoffman, JY Kang, et al. Acute depletion of BRG1 reveals its primary function as an activator of transcription. 2024, Nature Communications, 15 (1), 4561.

2.S Liu#, YQ Cao#, KR Cui#, G Ren, et al. Regulation of T helper cell differentiation by the interplay between histone modification and chromatin interaction. 2024, Immunity. 57 (5), 987-1004. e5.

3.MZ Zheng#, C Yao#, G Ren#, KR Mao, et al. Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues. Cell Reports. 2023 Aug 29; 42(8).

4.Gang Ren#; Binbin Lai; Christelle Harly; Songjoon Baek; Yi Ding; Mingzhu Zheng; Kairong Cui; Jinfang Zhu; Gordon L. Hager; Avinash Bhandoola; Keji Zhao. TCF-1 and GATA3 are key factors for epigenetic priming of EILPs toward distinct cell Fates. Immunity, 2022 Aug 9; 55(8):1402-1413.e4.

5.Yaqiang Cao#; Shuai Liu#; Gang Ren#; Qingsong Tang; Keji Zhao; cLoops2: a full-stack comprehensive analytical tool for chromatin interactions, Nucleic Acids Research, 2022, 50(1): 57-71.

6.T Zhen#, YQ Cao#, G Ren, Ling Zhao, et al. RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development. Blood. 2020 Nov 19;136(21):2373-2385.

7.G Ren#*, K Zhao*. CTCF and cellular heterogeneity. Cell & Bioscience 9 (1), 1-7.

8.Rodriguez J, Ren G, et al. Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity. Cell. 2019 Jan 10;176(1-2):213-226.e18.

9.C. Harly, D. Kenney, G. Ren, et al. The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage. Nat Immunol. 2019 Sep; 20(9): 1150–1160.

10. G Ren#, KR Cui#, CY Liu, JF Zhu and Keji Zhao*. Negative regulation of Ifng expression by MLL4 through CNS-28. J Immunol May 1, 2020, 204 (1 Supplement) 76.10.

11. Lai B, Tang Q, Jin W, Hu G, Wangsa D, Cui K, Stanton BZ, Ren G, Ding Y, et al. Trac-looping measures genome structure and chromatin accessibility. Nat Methods. 2018 Sep;15(9):741-747. 

12. G. Ren#, Jin W#, Cui K, Rodrigez J, Hu G, Zhang Z, Larson DR, Zhao K*.  CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression. Mol. Cell. 2017 Sep 21;67(6):1049-1058.e6.

13. Jin W, Tang Q, Wan M, Cui K, Zhang Y, Ren G, et al. Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples. Nature. 2015 (3); 528(7580):142-6.

14. G Ren#, KR Cui#, ZY Zhang*, KJ Zhao*. Division of labor between IRF1 and IRF2 in regulating different stages of transcriptional activation in cellular antiviral activities. Cell & Bioscience. 2015, 5: 17

15. Dowen JM#, Fan ZP,# Hnisz D#, Ren G#, Abraham BJ, Zhang LN, Weintraub AS, Schuijers J, Lee TI, Zhao K*, Young RA*. Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes. Cell. 2014 Oct 9; 159 (2):374-87.

联系方式：

Email: rengang666@nwafu.edu.cn 

欢迎有志于从事科研的学生报考硕、博研究生；常年欢迎有从事博士后研究意愿的学生联系，共同解锁大自然的奥秘！