一、本人简况

凌飞，1982年11月出生，安徽芜湖市人，博士，教授，博士生导师。2001年考入南京农业大学水产养殖学专业并于2005年获得农学学士学位，同年保送到中国科学院水生生物研究所水生生物学专业硕博连读于2010年获得理学博士学位。2010年7月至今，在西北农林科技大学动物科技学院水产科学系工作，从事水产动物病害学的教学与科研工作。入选国家级青年人才、“唐立新”优秀学者、西北农林科技大学“我最喜爱的老师”等。目前兼任中国新农科水产联盟理事、中国水产学会鱼病专业委员会委员、中国水产学会渔药专业委员会委员、陕西省渔业产业技术体系岗位专家、陕西省水产业技术创新战略联盟秘书长等。

二、教学情况

自工作以来，承担了本科生《水产药物学》《水产动物病害学》以及研究生《现代水产动物医学》《水生生物学研究进展》等课程。目前公开发表教改论文6篇（其中核心2篇），参与编写相关教材3部，主持校级教改项目3项，获得校级教学成果一等奖1项。

三、科研情况

主要研究方向为：（1）植物源渔药的创新与创制；（2）水产动物肠道微生物组学及益生菌的开发利用。

先后主持国家、省部级等课题15项，包括：3项国家自然科学基金（面上项目2项，青年项目1项）、教育部高等学校博士学科点专项科研基金、陕西省重点研发计划、陕西省农业科技攻关、中国博士后科学基金面上资助和中央高校基本科研业务费等。截止到2023年9月公开发表论文100余篇，其中以第一作者或通讯作者身份在The ISME Journal、Microbiome、Journal of Hazardous Materials、Journal of Nanobiotechnology、Aquaculture等杂志发表SCI刊源论文61篇（自然指数期刊1篇，IF>10的6篇）；参与编写著作1部；授权或申请发明专利21项，其中5项（第一完成人和第二完成各2项）已经成功转让，累计金额1501万元；获得陕西省自然科学奖二等奖1项；作为主要参与人获得农业农村部兽用生物制品临床试验批件2个。

2018年以来发表的主要学术论文（所有论文见https://publons.com/researcher/1249881/fei-ling/）

[1] Qi XZ, Zhang Y, Zhang YL, Luo F, Song KG, Wang GX*, Ling F*. Vitamin B-12 produced by  Cetobacterium somerae improves host resistance against pathogen infection through strengthening the interactions within gut microbiota.  Microbiome , 2023, 11:135. (中科院生物学1区，IF₂₀₂₂="15.5，TOP期刊)

[2] Song KG, Li J, Yang F, Wu ZB, Chen WC, Li PF, Ling F*, Wang GX*. Antiviral effect of prodigiosin isolated from fish intestinal bacteria against  Micropterus salmoides rhabdovirus.  Aquaculture , 2023, 574, 739683. (中科院农林科学1区，IF₂₀₂₂="4.5，TOP期刊)

[3] Zhang ZY, Jin ZL, Wang GX*, Ling F*. Mannosylated chitosan nanoparticles loaded with ABP antigen server as a novel nucleic acid vaccine against  Nocardia Seriolae infection in  Micropterus Salmoides .  Aquaculture , 2023, 574, 739635. (中科院农林科学1区，IF₂₀₂₂="4.5，TOP期刊)

[4] Qi XZ, Zhang YL, Wang GX, Ling F*. Gut redox potential affects host susceptibility to pathogen infection.  Aquaculture , 2023, 574, 739661. (中科院农林科学1区，IF₂₀₂₂="4.5，TOP期刊)

[5] Luo F, Song KG, Chen WC, Qi XZ, Zhang Y, Wang GX, Ling F*. Longitudinal analysis of changes in the gut microbiota of zebrafish following acute spring viremia of carp virus infection.  Aquaculture , 2023, 572, 739499. (中科院农林科学1区，IF₂₀₂₂="4.5，TOP期刊)

[6] Zhang Y, Qi XZ, Zhang ZY, Jin ZL, Wang GX*, Ling F*. Effects of dietary  Cetobacterium somerae on the intestinal health, immune parameters and resistance against  Nocardia seriolae of largemouth bass,  Micropterus salmoides. Fish Shellfish Immunol.,  2023, 135, 108693.  (中科院农林科学2区，IF₂₀₂₂="4.7，TOP期刊)

[7] Li J, Zhang Z, Wu ZB, Qu SY, Wang GX, Wei DD, Li PF*, Ling F*. Enterobacter asburiae  E7, a novel potential probiotic, enhances resistance to  Aeromonas veronii infection via stimulating the immune response in common carp ( Cyprinus carpio ).  Microbiol. Spectr. , 2023, 11, e04273-22. (中科院农林科学1区，IF₂₀₂₂="3.7，TOP期刊)

[8] Qu SY, Liu JT, Wu ZB, Li J, Li PF, Wang GX, Ling F*. Nanocomplexation is a promising strategy to enhance the solubility and anti- Ichthyophthirius multifiliis  activity of magnolol.  Aquaculture , 2023, 565, 739105. (中科院农林科学1区，IF₂₀₂₂="4.5，TOP期刊)

[9] Wang EL^#*, Zhou Y^#*, Liang Y^#, Ling F^#, Xue XS, He XL, Xue Y, Zhou CL, Tang G, Wang GX*. Rice flowering improves the muscle nutrient, intestinal microbiota diversity, and liver metabolism profiles of tilapia ( Oreochromis niloticus ) in rice-fish symbiosis. Microbiome, 10, 231. (中科院农林科学1区，IF₂₀₂₂="4.5，TOP期刊)

[10] Jin YJ, Yang F, Zhang GR, Yu Q, Wang GX, Ling F*, Liu TQ*. Synthesized magnolol derivatives improve anti- Micropterus salmoides  rhabdovirus (MSRV) activity  in vivo .  Viruses , 2022, 14, 1421. （中科院医学3区，IF₂₀₂₁="5.818）

[11] Li BY, Yang F, Zhang ZY, Shen YF, Wang T, Zhao L, Qin JC, Ling F*, Wang GX*. Quinoline, with the active site of 8-hydroxyl, efficiently inhibits  Micropterus salmoides rhabdovirus (MSRV) infection in vitro and in vivo.  J. Fish Dis. , 2022, 45:895-905. (中科院农林科学2区，IF="2.318)

[12] Zhang GR, Li LH, Zhou GQ, Lin ZY, Wang J, Wang GX, Ling F*, Liu TQ*. Recyclable aminophenylboronic acid modified bacterial cellulose microspheres for tetracycline removal: Kinetic, equilibrium and adsorption performance studies for hoggery sewer.  Environ. Pollut. ,  2022, 307:119544.(中科院环境科学与生态学2区，IF₂₀₂₁="9.988)

[13] Song KG, Wang H, Jiao Z, Qu, GZ*, Chen WC, Wang GX, Wang TC, Zhang ZQ, Ling F* . Inactivation efficacy and mechanism of pulsed corona discharge plasma on virus in water.  J. Hazard. Mater. , 2022, 422, 126906.  (中科院环境科学与生态学1区，IF₂₀₂₁="14.224，TOP期刊)

[14] Qu SY, Tan XP, Li BK, Wang GX*, Ling F*. 

Malformed largemouth bass ( Micropterus salmoides ) are more susceptible and vulnerable to  Ichthyophthirius multifiliis  infections: Immunological and histopathological study.  Aquaculture , 2022, 548, 737664. (中科院农林科学1区，IF₂₀₂₁="5.135，TOP期刊)

[15] Zhang Z, Cui HB, Zhang ZQ, Qu SY, Wang GX, Ling F*. Pharmacokinetics of magnolol following different routes of administration to goldfish ( Carassius auratus ) and its oral efficacy against Ichthyophthirius multififiliis infection.  Aquaculture , 2022, 546, 737356. (中科院农林科学1区，IF₂₀₂₁="5.135，TOP期刊)

[16] Song KG, Luo F, Chen WC, Qi XZ, Shen YF, Zha JW, Ling F*, Wang GX*. Evaluation on the antiviral activity of Bacillus velezensis exreact against spring viremia of carp virus.  Aquaculture , 2022, 547, 737477. (中科院农林科学1区，IF₂₀₂₁="5.135，TOP期刊)

[17] Zhang ZY, Liu GY, Liu JY, Zhu B, Wang GX*, Ling F*. Epitope screening of the major capsid protein within grouper iridovirus of Taiwan and the immunoprotective effect with SWCNTs as the vaccine carrier.  Fish Shellfish Immunol. ,2021,117,17-23. (中科院农林科学2区，IF₂₀₂₀="4.581, TOP期刊)

[18] Wu ZB, Qi XZ, Qu SY, Ling F*, Wang GX*. Dietary supplementation of  Bacillus velezensis  B8 enhances immune response and resistance against  Aeromonas veronii  in grass carp.  Fish Shellfish Immunol. ,2021,115,14-21.(中科院农林科学2区，IF₂₀₂₀="4.581, TOP期刊)

[19] Yang F, Song KG, Zhang ZY, Chen C, Wang GX, Yao JY*, Ling F*. Evaluation on the antiviral activity of ribavirin against  Micropterus salmoides rhabdovirus (MSRV) in vitro and in vivo.  Aquaculture , 2021, 543, 736975. (中科院农林科学1区, IF₂₀₂₀="4.242, TOP期刊)

[20] Qu SY, Song CG, Tan XP, Wang GX, Ling F*. Comparative proteomic analysis provides insight into the key proteins as potential targets underlying the effect of malachite green against  Ichthyophthirius multifiliis. J. Fish Dis.  2021, 44:881-92.

(中科院农林科学2区，IF=2.318)

[21] Ling F, Steinel N, Weber J, Ma L, Smith C, Correa D, Zhu B, Bolnick D*, Wang GX*. The gut microbiota response to helminth infection depends on host sex and genotype.  ISME J., 2020, 14:1141-53. (中科院环境科学与生态学1区，IF="9.493，自然指数期刊，TOP期刊)

[22] Qi XZ, Xue MY, Cui HB, Yang KC, Song KG, Zha JW, Wang GX*, Ling F*. Antimicrobial activity of  Pseudomonas monteilii JK-1 isolated from fish gut and its major metabolite, 1-hydroxyphenazine, against  Aeromonas hydrophila. Aquaculture,  2020, 526:735366.

(中科院农林科学1区，IF=3.224，TOP期刊)

[23] Yang KC, Qi XZ, He MS, Song KG, Luo F, Qu XY, Wang GX*, Ling F*.

Dietary supplementation of salidroside increases immune response and disease resistance of crucian carp ( Carassius auratus ) against  Aeromonas hydrophila .  Fish Shellfish Immunol. , 2020, 106:1-7.

[24] Tu X, Tan XP, Qi XZ, Huang AG, Ling F*, Wang GX*. Proteome interrogation using gold nanoprobes to identify targets of arctigenin in fish parasites.  J. Nanobiotechnol , 2020, 18:32. (中科院工程技术2区，IF="6.518)

[25] Zhang ZY, Liu GY, Ma R, Qi XZ, Wang GX, Zhu B*, Ling F*.

The immunoprotective effect of whole-cell lysed inactivated vaccine with SWCNT as a carrier against  Aeromonas hydrophila infection in grass carp.

Fish Shellfish Immunol. , 2020, 97:336-43.

[26] Luo F, Zhu S, Hu Y, Yang KC, He MS, Zhu B, Wang GX*, Ling F*. Biocompatibility assessment of Fe₃O₄ nanoparticles using  Saccharomyces cerevisiae as a model organism.  Comp. Biochem. Physiol. C Toxicol. Pharmacol. , 2020, 227:108645. (中科院环境科学与生态学3区，IF="2.892)

[27] Qi XZ, Tu X, Zha JW, Huang AG, Wang GX, Ling F*.

Immunosuppression-induced alterations in fish gut microbiota may increase the susceptibility to pathogens.  Fish Shellfish Immunol. , 2019, 88:540-5.

(中科院农林科学1区，IF=3.298，TOP期刊)

[28] Hu Y, Shen YF, Tu X, Wu XH, Wang GX, Ling F*. Isolation of anti-Saprolegnia lignans from Magnolia offcinalis and SAR evaluation of honokiol/magnolol analogs.  Bioorg. Med. Chem. Lett., 2019, 29:389-95. (中科院医学3区，IF="2.572)

[29] Li J, Wu ZB, Zhang Z, Zha JW, Qu SY, Qi XZ, Wang GX*, Ling F*. Effects of potential probiotic  Bacillus velezensis K2 on growth, immunity and resistance to  Vibrio harveyi infection of hybrid grouper ( Epinephelus lanceolatus ♂ × E. fuscoguttatus♀).  Fish Shellfish Immunol. , 2019, 93:1047-55. (中科院农林科学1区，IF="3.298，TOP期刊)

[30] Hao K, Chen XH, Qi XZ, Zhu B, Wang GX*, Ling F*. Display of GCRV vp7 protein on the surface of  Escherichia coli and its immunoprotective effects in grass carp ( Ctenopharyngodon idella ).  Fish Shellfish Immunol. , 2018, 72:199-209. (中科院农林科学1区，IF="3.298，TOP期刊)

[31] Tu X, Huang AG, Hu Y, Ling F*, Wang GX*. Arctigenin: An emerging candidate against infections of  Gyrodactylus .  Aquaculture , 2018, 495:983-91. (中科院农林科学1区，IF="3.224，TOP期刊)

[32] Yu XB, Hao K, Li J, Chen XH, Wang GX*, Ling F*. Effects of moroxydine hydrochloride and ribavirin on the cellular growth and immune responses by inhibition of GCRV proliferation.  Res. Vet. Sci. , 2018, 117:37-44. (中科院农林科学3区，IF="1.892)

[33] Chen XH, Hao K, Yu XB, Huang AG, Zhu B, Wang GX*, Ling F*. Magnolol protects  Ctenopharyngodon idella kidney cells from apoptosis induced by grass carp reovirus. Fish Shellfish Immunol., 2018, 74:426-35. (中科院农林科学1区，IF="3.298，TOP期刊)

[34] Song CG, Song KG, Wu XH, Tu X, Qi XZ, Wang GX, Ling F*. Antiparasitic efficacy and safety assessment of magnolol against  Ichthyophthirius multifiliis in goldfish. Aquaculture, 2018, 486:9-17. 1.

(中科院农林科学1区，IF=3.224，TOP期刊)

三、联系方式

通讯地址：陕西杨凌西农路22号西北农林科技大学动物科技学院131室

邮编：712100

Email: feiling@nwafu.edu.cn