西北农林科技大学 动物科技学院
师资队伍
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陈宏

来源:   作者:   发布日期:2015-10-16 浏览次数:

  

  

  1.基本信息

  陈宏,男,陕西省西安市人,遗传学博士、博士后,教授(二级),现为西北农林科技大学动物遗传育种与繁殖学科、遗传学学科博士生导师、学术带头人、动物科学系主任。国务院政府特殊津贴获得者、全国优秀农业科教工作者、陕西省高等学校教学名师、陕西省师德标兵、西北农林科技大学拔尖人才支持计划入选者、西北农林科技大学“教学名师支持计划”入选者,2012年获全国宝钢优秀教师奖。1996年5月至1998年9月在德国耶拿大学做博士后研究;1992年9月至1996年4月在德国萨尔大学攻读遗传学博士学位;1991年8月至1992年9月在德国吉森大学作访问学者;1987年9月至1990年10月在西北农业大学畜牧系攻读动物遗传育种学硕士学位;1978年2至月1981年12月在西北农学院畜牧兽医系上畜牧专业本科,获学士学位。

  兼任第四、第五届国家教育部科学技术委员会生命科学部委员;国家肉牛牦牛产业技术体系遗传育种岗位专家;中国细胞生物学学会常务理事;中国畜牧兽医学会动物遗传标记学分会副理事长;中国畜牧兽医学会养牛学分会副理事长;中国农业生物技术学会动物生物技术学分会理事;中国畜牧兽医学会动物遗传育种学分会理事;中国黄牛育种委员会常务理事兼副秘书长;中国肉牛经济专业委员会常务理事;中国牛业协会理事;农业部教材建设专家委员会委员;中国西门塔尔牛育种委员会理事;陕西省学位委员会委员;陕西省遗传学会副理事长;陕西省秦川牛产业协会副理事长;陕西省细胞生物学学会副理事长;陕西省生物化学与分子生物学学会副理事长;《中国牛业科学》杂志主编;《中国农业科学》栏目主审专家、《遗传》、《西北农林科技大学学报》、《现代生物医学进展》、《中国组织工程研究与临床康复》、《中国草食动物》编委;曾任西北农林科技大学学术委员会委员、西北农林科技大学第七、第八届学位委员会委员;西北农林科技大学生物技术中心和陕西省农业分子生物学重点实验室副主任兼动物部主任;西北农林科技大学动物科技学院教授委员会副主任;国家科技进步奖、发明奖、教育部科技进步奖评审专家,国家自然科学基金通讯评审、二审会评专家;担任BMC Genomics, Scientific Reports、Plos one,Animal Genetics, Gene, Genome, Molecular Biology Reports, Livestock Science, Small Ruminant Research, Biochemical Genetics, Journal of Assisted Reproduction and Genetics等二十余种SCI期刊以及《中国科学》、《中国农业科学》、《畜牧兽医学报》、《农业生物技术学报》、《生态学报》等期刊的审稿专家。

  2.研究方向

  生物技术与家畜育种,动物基因组与功能研究、动物遗传资源与利用研究。

  3.教学及成果

  多年来,一直从事动物遗传育种,细胞遗传、分子遗传、动物基因工程和现代生物技术等教学工作。先后承担本科《动物遗传学》、《动物育种学》、《基因工程》、《牛生产学》和《学科导论》,硕士研究生《分子遗传学》、《细胞遗传学》、《蛋白质组学》和《动物基因工程》,博士研究生《遗传育种研究专题》、《现代生物技术专题》等课程。

  先后编写教材和论著12部,其中主编国家十一五规划教材《基因工程》(第二版)、十二五规划教材《基因工程实验技术》(第二版)、面向21世纪全国统编教材《基因工程原理与应用》和《基因工程实验技术》、副主编全国统编教材《新编遗传学教程》、《动物分子生物学》、《动物遗传资源学》和《中国黄牛学》,参编国家十二规划教材《动物遗传学》、《现代生物技术概论》、《国外动物生产新技术》和《动物种业科技创新战略研究报告》,主编全国高等农业教育《基因工程》精品共享课程资源电子版书,主编成人教育教材《动物遗传育种学》;并自编教材《动物遗传学实验指导》(本科用)、《细胞遗传学实验指导》(研究生用)和《分子遗传学实验指导》(研究生用)及《遗传学习题集》等。2006年《基因工程原理与应用》获全国农林高校优秀教材,2007年获陕西省优秀教材二等奖。2001年“动物遗传育种系列课程教学改革与实践”获陕西省教学优秀成果二等奖。2007年“遗传工程教学实验示范中心创建及开放运行机制探讨”获陕西省教学优秀成果一等奖。所负责的《动物遗传学》于2009年获得“国家级精品课程”,所负责的动物遗传学教学团队2010年获“陕西省教学团队”,2013年《动物遗传学》被评为国家资源共享课,2010年获得西北农林科技大学“教学名师支持计划”、2010年获得《分子遗传学》研究生优质课程支持计划。2015年《基因工程》获陕西省优秀教材二等奖。已培养硕士研究生94名,博士研究生52名(其中1人次获“全国优秀博士学位论文提名”,2人次获“陕西省优秀博士学位论文”,3人获得教育部博士学术新人奖,多人次获得“校长优秀论文奖励基金”和国家奖学金;目前在读硕士研究生10名,博士研究生12名。

  4.科研及成果

  多年来,一直从事肉牛、奶牛和山羊等生物技术与家畜育种,动物基因组与功能、动物遗传资源与利用等方面的科学研究工作。多年来,先后主持863计划项目3项,主持子项目3项;主持国家自然科学基金项目6项、国家支撑计划子项目2项、国家肉牛转基因育种重大专项子课题3项,中华农业科教基金、教育部博士点基金、国家肉牛产业技术体系项目、陕西省“13115”重点项目、陕西省科技统筹创新项目、河南省杰出人才基金项目、江苏省和陕西省自然科学基金项目等各类科研项目40余项。

  在肉牛、奶牛、奶山羊重要经济性状相关功能基因挖掘和应用研究、肌肉生长与肉质的表观遗传调控机制、家畜遗传资源评价、遗传多样性与分子进化等方面已取得了重要研究进展。已在国内外重要学术期刊发表论文400余篇,其中第一与通讯作者发表SCI收录论文300余篇。获得各类科技奖项30余次,其中获国家科技进步二等奖1项,获得省科技进步一等奖3项、二等奖2项,三等奖3项。陕西省自然科学优秀论文一、二、三等奖5项。获得国家发明专利43项。

  多年来的研究成果分别发表在《 Molecular Therapy-Nucleic Acids 》、《 Cell Death and Disease 》、《 Epigenetic 》、《 Biochimica et   Biophysica Acta - Gene Regulatory Mechanisms 》、《 Biochimica et BiophysicaActa (BBA)-Molecular Cell Research 》、《 Journal of Agricultural and Food Chemistry 》、《 Journal of Functional Foods 》、《 Journal of Cellular Physiology 》、《 Journal of Cellular Biochemistry 》、《 Scientific Reports 》、《 BMC Genomics 》、《 RNA B iology 》、《 Oncotarget 》、《 J ournal of A nimal S cience 》、《 Histochemistry and Cell Biology 》、《 International Journal of molecular Sciences 》、《 Plos one 》、《 Genetics Selection Evolution 》、《 Animal Genetics 》、《 Journal of Animal Science and Biotechnology 》、《 Mamm Genome 》、《 SCIENCE CHINA Life Sciences 》、《 Analytical Biochemistry 》、《 Genetica 》、《 Research in Veterinary Science 》、《 Biochemical and Biophysical Research Communications 》、《 Analytical methods 》、《 General and Comparative Endocrinology 》、《 Veterinary Immunology and Immunopathology 》、《J ournal of Genetics and Genomics 》、《 Gene 》、《 Genome 》、《 Comp. Biochem. Physiol .》、《 Molecular Biology Reports 》、《 Molecular Biotechnology 》、《 Journal of Biosciences 》、《 Livestock Science 》、《 Small Ruminant Research 》、《 Canadian Journal of Animal Sciences 》、《 J Virol Methods 》、《遗传学报》、《动物学报》、《中国农业科学》、《畜牧兽医学报》、《生物工程学报》、《中国生物化学与分子生物学学报》、《农业生物技术学报》等国内外重要学术刊物上。

  5.发表的部分论文如下:*: 通讯作者

  2019年:

  Xiu-Kai Cao#, Jie Cheng#, Yong-Zhen Huang#, Xiao-Gang Wang, Yu-Lin Ma, Shu-Jun Peng, Buren Chaogetu, Zhaxi Zhuoma, and Hong Chen*. Growth Performance and Meat Quality Evaluations in Three-Way Cross Cattle Developed for the Tibetan Plateau and their Molecular Understanding by Integrative Omics Analysis. Journal of Agricultural and Food Chemistry ,2019, 67, 541−550.

  Jian WangChengchuang Song ,Xiukai CaoHui LiYilei MaYongzhen HuangXianyong LanChuzhao LeiYun MaYueyu BaiFengpeng Lin ,Hong Chen*. MiR‐208b regulates cell cycle and promotes skeletal muscle cell proliferation by targeting CDKN1A. J ournal of Cellular Physiolog y,2019,234: 3720–3729.

  Wu Jiyao, Yue Binglin, Lan Xianyong, Wang Yanhuan, Fang Xingtang, Ma Yun, Bai Yueyu, Qi Xingshan, Zhang Chunlei*,Chen Hong*. MiR-499 regulates myoblast proliferation and differentiation by targeting transforming growth factor beta receptor 1. J ournal of Cellular Physiolog y,2019, 234(3):2523-2536.

  Chengchuang Song, Zhaoxin Yang, Dong Dong, Jiawei Xu, Jian Wang, Hui Li, Yongzhen Huang, Xianyong Lan,Chuzhao Lei,Yun Ma,Hong Chen* miR-483 regulates cattle muscle cells growth and differentiation through IGF1/AKT signal pathway. Journal of Cellular Physiology , 2019,234(6): 9839-9848.

  Chengchuang Song#, Jiameng Yang#, Rui Jiang, Hui Li, Zhaoxin Yang, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Yun Ma, Xinglei Qi, Hong Chen*. Overexpression of miR-148a-3p regulates proliferation and apoptosis of bovine muscle cells by targeting KLF6 . Journal of Cellular Physiology , 2019.1.13, Accepted: DOI: 10.1002/jcp.28232。

  Binglin Yue, Hui Li, Mei Liu, Mingxun Li, Jiyao Wu, Chuzhao Lei, Bizhi Huang, Hong Chen*. Characterization of lncRNA–miRNA–mRNA network to reveal potential functional ceRNAs in bovine skeletal muscle.  Fr on tiers in Genetics ,2019,2,Accepted.

  Mei Liu, Bo Li, Wenwen Peng, Yilei Ma, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, George E. Liu, Xinglei Qi,Hong Chen*. LncRNA-MEG3 promotes bovine myoblast differentiation by sponging miR-135. Journal of Cellular Physiology, 2019.2. Accepted.

  Mei Liu, Lingzhao Fang, Shuli Liu, Michael G. Pan, Eyal Seroussi, Li Ma, Hong Chen*, George E. Liu*. Array CGH based detection of CNV regions and their potential association with reproduction and other economic traits in Holsteins. BMC genomics , 2019.2. Accepted.

  2018年:

  Hui Li#, Jiameng Yang#, Rui Jiang, Xuefeng Wei, Chengchuang Song, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Yun Ma, Linyong Hu, Hong Chen*. Long non-coding RNA profiling reveals an abundant MDNCR that promotes differentiation of myoblasts via sponging miR-133a. Molecular Therapy: Nucleic Acids , 2018, 12: 610-625.

  Hui Li#, Xuefeng Wei#, Jiameng Yang#, Dong Dong, Dan Hao, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Yun Ma, Fengpeng Lin, Yueyu Bai, and Hong Chen*. circFGFR4 Promotes Differentiation of Myoblastsvia Binding miR-107 to Relieve Its Inhibition of Wnt3a. Molecular Therapy: Nucleic Acids , 2018, 11: 272-283.

  Chengchuang Song#, Jian Wang#, Yilei Ma, Zhaoxin Yang, Dong Dong, HuiLi, Jiameng Yang, Yongzhen Huang, Martin Plath, Yun Ma & Hong Chen*. Linc-smad7promotes myoblast differentiation and muscle regeneration via sponging miR-125b. Epigenetics,  2018,13(6):591-604.

  Hui Li#, Jiameng Yang#, Xuefeng Wei#, Chengchuang Song, Dong Dong, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Yun Ma, Xinglei Qi, Yueyu Bai, Hong Chen*. CircFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a.  Journal of Cellular Physiology ,  2018, 233:4643–4651.

  Yuan‐Chao Sun, Yong‐Yong Wang, Xiao‐Feng Sun, Shun‐Feng Cheng, Lan Li, Yong Zhao, Wei Shen*, Hong Chen*. The role of autophagy during murine primordial follicle assembly. AGING ,  2018, 10(2): 197-211. www.aging‐us.com.

  Hanfang Cai#, Mingxun Li#, Xiaomei Sun, Martin Plath, Cong-jun Li, Xianyong Lan, Chuzhao Lei, Yongzhen Huang, Yueyu Bai, Xinglei Qi, Fengpeng Lin and Hong Chen*“Global transcriptome analysis during adipogenic differentiation and involvement of transthyretin gene in adipogenesis in cattle”, Frontiers in Genetic s . 2018,9:463.

  Yongzhen Huang, Xinsheng Lai, Linyong Hu, Chuzhao Lei, Xianyong Lan, Chunlei Zhang, Yun Ma, Li Zheng, Yue-Yu Bai, Fengpeng Lin, Hong Chen*. Over-expression of DEC1 inhibits myogenic differentiation by modulating MyoG activity in bovine satellite cell.  J ournal of Cellular Physiolog y,2018, 233(12):9365-9374.

  Yujia Sun, Kunpeng Liu, Yongzhen Huang, Xianyong Lan, Hong Chen*, Differential expression of FOXO1 during development and myoblast differentiation of Qinchuan cattle and its association analysis with growth traits.  SCIENCE CHINA Life Sciences , 2018, 61(7): 826-835.

  Yao Xu, Tao Shi, Yang Zhou, Mei Liu, Sebastian Klaus, Xianyong Lan, Chuzhao Lei, Hong Chen*.A novel PAX7 10-bp indel variant modulates promoter activity, gene expression and contributes to different phenotypes of Chinese cattle. Scientific Reports , 2018, 8:1724.

  Xiu-Kai Cao, Yong-Zhen Huang, Yi-Le Ma, Jie Cheng, Zhen-Xian Qu, Yun Ma, Yue-Yu Bai, Feng Tian, Feng-Peng Lin, Yu-Lin Ma, Hong Chen*. Integrating CNVs into meta-QTL identified GBP4 as positional candidate for adult cattle stature. Functional & Integrative Genomics ,  2018, 1-9.

  Xuefeng Wei#,Hui Li#,Guangwei ZhaoJiameng YangLihui LiYongzhen HuangXianyong LanYun MaLinyong HuHuiling ZhengHong Chen*. ΔFosB regulates rosiglitazone‐induced milk fat synthesis and cell survival。 J ournal of Cellular Physiolog y,2018,233(12):9284-9298.

  2017年:

  Xuefeng Wei, Hui Li, Jiameng Yang, Dan Hao, Dong Dong, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Fengpeng Lin, Yueyu Bai and Hong Chen*. Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p. Cell Death and Disease  (2017) 8, e3153; doi:10.1038/cddis.2017.541; published online 26 October 2017

  Hui Li, Xuefeng Wei, Jiameng Yang, Dong Dong, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Xinglei Qi, Yueyu Bai and Hong Chen*. Developmental transcriptome profiling of bovine muscle tissue reveals an abundant GosB that regulates myoblast proliferation and apoptosis. Oncotarget, 2017, Vol. 8, (No. 19), pp: 32083-32100.

  Mingjuan Yang , Jingqiao Lv, Liangzhi Zhang, Mingxun Li, Yang Zhou, Xianyong Lan, Chuzhao Lei, Hong Chen*. Association study and expression analysis of CYP4A11 gene copy number variation in Chinese cattle. Scientific Reports ,  2017, 7:46599. DOI: 10.1038/srep46599

  Zhuanjian Li, Xianyong Lan, Ruili Han*, Jing Wang, Yongzhen Huang, Jiajie Sun, Wenjiao Guo & Hong Chen*. miR-2478 inhibits TGFβ1 expression by targeting the transcriptional activation region downstream of the TGFβ1 promoter in dairy goats. Scientific Reports , 2017, 7: 42627. DOI: 10.1038/srep42627

  Mei Liu, Bo Li, Yongzhen Huang, Mingjuan Yang, Xianyong Lan, Chuzhao Lei, Weidong Qu, Yueyu Bai*, Hong Chen*. Copy number variation of bovine MAPK10 modulates the transcriptional activity and affects growth traits.  Livestock Science ,  2016, 194: 44–50.

  K.X. Cao, D.Hao, J.Wang, W.W. Peng, Y.J. Yan, H.X. Cao, F. Sun, H. Chen*. Cold exposure induces the acquisition of brown adipocyte gene expression profiles in cattle inguinal fat normalized with a new set of reference genes for qRT-PCR. Research in Veterinary Science 2017, 114: 1–5.

  Yao Xu, Yu Jiang, Tao Shi, Hanfang Cai, Xianyong Lan, Xin Zhao, Martin Plath, Hong Chen*. Whole-genome sequencing reveals mutational landscape underlying phenotypic differences between two widespread Chinese cattle breeds. PLoS ONE , 2017,12(8): e0183921.

  Yuan-Chao Sun, Xiao-Feng Sun, Paul W. Dyce, Wei Shen*, Hong Chen*. The role of germ cell loss during primordial follicle assembly: a review of current advances . International Journal of Biological Sciences ,2017; 13(4): 449-457. doi: 10.7150/ijbs.18836

  Yan Hong Wang,Jun Qiang Liu,Hui Wu,Xing Tang Fang,Hong Chen*,Chun Lei Zhang*。Amino acids regulate mTOR pathway and milk protein synthesis in a mouse mammary epithelial cell line is partly mediated by T1R1/T1R3。 European Journal of Nutrition , 2017, 56(8):2467–2474。

  Binglin Yue, Jiyao Wu, Yanhuan Wang, Chunlei Zhang, Xingtang Fang, and Hong Chen*. Expression Profiles Analysis and Functional Characterization of MicroRNA-660 in Skeletal Muscle Differentiation. Journal of Cellular Biochemistry ,  2017 , 118:2387–239.

  2016年:

  Mingxun Li, Xiaomei Sun, Hanfang Cai, Yujia Sun ,Martin Plath, CongjunLi, Xianyong Lan,Chuzhao Lei, Fengpeng Lin, Yueyu Bai*, Hong Chen*. Long non-coding RNA ADNCR suppresses adipogenic differentiation by targeting miR-204. Biochimica et   Biophysica Acta , 2016,1859:871–882. (IF="5.373)

  Wei X, Li H, Zhang B, Li C, Dong D, Lan X, Huang Y, Bai Y, Zhao X, Chen H*.miR-378a-3p Promotes Differentiation and Inhibits Proliferation of Myoblasts by Targeting HDAC4 in Skeletal Muscle Development.  RNA Biology ,  2016, 13(12): 1300-1309.

  Mingxun Li,Xiaomei Sun,Yang Zhou,Xuefeng Wei,Yujia Sun,Xianyong Lan,Chuzhao Lei,Hong Chen*。Nicotinamide and resveratrol regulate bovine adipogenesis through a SIRT1-dependent mechanism. Journal of Functional Foods, 2015,18:492–500. (IF="3.973)

  Xiaomei Sun, Mingxun Li, Yujia Sun, HanfangCai, XianyongLan, Yongzhen Huang, YueyuBai, Xinglei Qi, Hong Chen*.  The developmental transcriptome sequencing of bovine skeletal muscle reveals a long noncoding RNA, lncMD, promotes muscle differentiation by sponging miR-125b.   Biochimica et BiophysicaActa (BBA)-Molecular Cell Research ,  2016, 1863(11): 2835-2845. (IF="5.128)

  X. Sun, M. Li, Y. Sun, H. Cai, R. Li, X. Wei, X. Lan, Y. Huang, C. Lei, and H. Chen*. The evelopmental transcriptome landscape of bovine skeletal muscle defined by Ribo-Zero ribonucleic acid sequencing. J ournal of A nimal S cience , 2015, 93:5648–5658. (IF="2.108)

  Yang Zhou,Lingyang Xu,DerekM. Bickhart,ElHamidiabdel Hay,StevenG. Schroeder,ErinE. Connor, LeesonJ. Alexander, TadS. Sonstegard, CurtisP. Van Tassell, Hong Chen*, and George E.Liu*. Reduced representation bisulphite sequencing of ten bovine somatic tissues reveals DNA methylation patterns and their impacts on gene expression. BMC Genomics ,2016,17: 779.(IF="3.867)

  Lan Li,Jing-Cai Liu,Fang-Nong Lai,Huan-Qi Liu,Xi-Feng Zhang,Paul W. Dyce,Wei Shen,Hong Chen*. Di(2-ethylhexyl) Phthalate Exposure Impairs Growth of Antral Follicle in Mice. PLOS ONE,  2016, e.0148350(IF="3.057)

  Zhang, BW,Cai, HF,Wei, XF,Sun, JJ ,Lan, XY,Lei, CZ,Lin, FP,Qi, XL,Plath, M,Chen, H*. miR-30-5p Regulates Muscle Differentiation and Alternative Splicing of Muscle-Related Genes by Targeting MBNL. International journal of molecular sciences ,  2016, 17(2): 182. (IF="3.257)

  Wang Y, Liu J, Wu H, Fang X, Chen H*, Zhang C*. Amino acids regulate mTOR pathway and milk protein synthesis in a mouse mammary epithelial cell line is partly mediated by T1R1/T1R3. Eur J Nutr.  2016 doi:10.1007/s00394-016-1282-1 (SCI 2区 IF2016= 3.239)

  2015年:

  J. Wang, L.S. Hua, H. Pan, L.Z. Zhang, M.X. Li, Y.Z. Huang, X.Y. Lan, C.Z. Lei and H. Chen*. Haplotypes of cis-acting elements in CIDEC gene possessing different transcriptional activities associated with body weight and average daily gain.  Scientific Reports. 2015,(5):720.(IF="5.578)

  Liangzhi Zhang; Shangang Jia; Martin Plath; Yongzhen Huang; Congjun Li; Chuzhao Lei; Xin Zhao; Hong Chen*. Impact of parental Bos taurus and Bos indicus origins on copy number variation in traditional Chinese cattle breeds. Genome Biology and Evolution, Genome Biol. Evol. 2015,7(8): 2352–2361.

  Lan Li, Jing-Cai Liu, Yong Zhao, Fang-Nong Lai, Fan Yang, Wei Ge, Cheng-Li Dou, Wei Shen, Xi-Feng Zhang, Hong Chen*. Impact of diethylhexyl phthalate on gene expression and development of mammary glands of pregnant mouse. Histochemistry and Cell Biology , 2 015,144:389–402. (IF="3.054).

  Mingxun Li,Xiaomei Sun,Yang Zhou,Xuefeng Wei,Yujia Sun,Xianyong Lan,Chuzhao Lei,Hong Chen*. Nicotinamide and resveratrol regulate bovine adipogenesis through a SIRT1-dependent mechanism. Journal of Functional Foods,  2015,18:492–500.(IF="3.574)

  X. Sun, M. Li, Y. Sun, H. Cai, R. Li, X. Wei, X. Lan, Y. Huang, C. Lei, and H. Chen*. The evelopmental transcriptome landscape of bovine skeletal muscle defined by Ribo-Zero ribonucleic acid sequencing. J ournal of A nimal S cience , 2015, 93:5648–5658.

  Hanfang Cai, Yang Zhou, WenchaoJia, BowenZhang, Xianyong Lan, Chuzhao Lei, Xintang Fang and Hong Chen*. Effects of SNPs and alternative splicing within HGF gene on its expression patterns in Qinchuan cattle.  Journal of Animal Science and Biotechnology,  2015, 6:55-62. (IF="2.037)

  Yong‐Zhen Huang, Yu‐Jia SunMing‐Xun Li, Jing Wang, Jia‐Jie Sun, Chun‐Lei Zhang, Yu‐Tang Jia, Hong Chen*. Evaluation of the causality of the zinc finger BED-type containing 6 gene (ZBED6) for six important growth traits in Nanyang beef cattle. Animal Genetics, 2015,46(2):225-226. DOI:10.1111/age.12265(IFr="2.21)

  Yong-Zhen HuangYong-Jie JingYu-Jia SunXian-Yong LanChun-Lei ZhangEn-Liang SongHong Chen*. Exploring genotype–phenotype relationships of the LHX3 gene on growth traits in beef cattle. Gene2015,561(2):219–224(IF=2.138)

  Yujia Sun ,XianyongLan , Chuzhao Lei , Chunlei Zhang ,Hong Chen*. Haplotype combination of the bovine CFL2 gene sequence variants and association with growth traits in Qinchuan cattle.  Gene ,2015,563(2): 136–141.

  J. Sun, T. S. Sonstegard, C. Li, Y. Huang1, Z. Li, X. Lan, C. Zhang, C. Lei, X. Zhao and H. Chen*. Altered microRNA expression in bovine skeletal muscle with age. Animal Genetics,2015,46(3):227–238.

  Y. H. Wang , C. L. Zhang , M. Plath, X. T. Fang , X. Y. Lan, Y. Zhou and H. Chen*. Global transcriptional profiling of longissimus thoracis muscle tissue in fetal and juvenile domestic goat using RNA sequencing. Animal Genetics, 2015,46:655–665.

  Zi-nian Wang, Han-fang Cai, Ming-xun Li, Xiu-kai Cao, Xian-yong Lan, Chu-zhao Lei, Hong Chen*. Tetra-primer ARMS-PCR identified four pivotal genetic variations in bovine PNPLA3 gene and its expression patterns。 Gene ,2016,575(2):.(IF="2.138)

  Zhang C, Wu H, Wang Y, Zhao Y, Fang X, Chen C, Chen H*. Expression Patterns of Circular RNAs from Primary Kinase Transcripts in the Mammary Glands of Lactating Rats.  Journal of Breast Cancer, 2015,Sep;18(3):235-41.

  2014年:

  Yong-Zhen Huang, Liang-Zhi Zhang, Xin-Sheng Lai, Ming-Xun Li, Yu-Jia Sun, Cong-Jun Li, Xian-Yong Lan, Chu-Zhao Lei, Chun-Lei Zhang, Xin Zhao & Hong Chen*. Transcription Factor ZBED6 Mediates IGF2 Gene Expression by Regulating Promoter Activity and DNA Methylation in Myoblasts. Scientific Reports ,2014,4 : 4570.

  Yong-Zhen Huang,Jia-Jie Sun, Liang-Zhi Zhang, Cong-Jun Li, James E. Womack, Zhuan-Jian Li, Xian-Yong Lan, Chu-Zhao Lei, Chun-Lei Zhang, Xin Zhao & Hong Chen*. Genome-wide DNA Methylation Profiles and Their Relationships with mRNA and the microRNA Transcriptome in Bovine Muscle Tissue (Bos taurine).  Scientific Reports ,2014,4: 6546.

  Liangzhi Zhang,Shangang Jia,Mingjuan Yang,Yao Xu,Congjun Li,Jiajie Sun,Yongzhen Huang,Xianyong Lan,Chuzhao Lei,Yang Zhou,Chunlei Zhang,Xin Zhao,and Hong Chen*. Detection of copy number variations and their effects in Chinese bulls. BMC Genomics ,2014,15:480.

  Liushuai Hua, Jing Wang, Mingxun Li, Xiaomei Sun, Liangzhi Zhang, Chuzhao Lei, Xianyong Lan, Xingtang Fang, Xin Zhao, Hong Chen*. An Asp7Gly Substitution in PPARG Is Associated with Decreased Transcriptional Activation Activity. PLoS ONE ,2014,9(1): e86954.

  Jiajie Sun, Yang Zhou, Hanfang Cai, Xianyong Lan, Chuzhao Lei, Xin Zhao, Chunlei Zhang, Hong Chen*.  Discovery of Novel and Differentially Expressed MicroRNAs between Fetal and Adult Backfat in Cattle.  PLoS ONE ,2014,9(2):e90244.

  Jiajie Sun  Bowen Zhang, Xianyong Lan, Chunlei Zhang, Chuzhao Lei, Hong Chen*. Comparative Transcriptome Analysis Reveals Significant Differences in MicroRNA Expression and Their Target Genes between Adipose and Muscular Tissues in Cattle. PLoS ONE ,2014,9(7):e102142.

  Yang Zhou, Jiajie Sun, Congjun Li, Yanhong Wang, Lan Li, Hanfang Cai, Xianyong Lan, Chuzhao Lei, Xin Zhao, Hong Chen*. Characterization of Transcriptional Complexity during Adipose Tissue Development in Bovines of Different Ages and Sexes.  PLoS ONE, 2014,9(7):e101261.

  Yanhong Wang, Chunlei Zhang, Xingtang Fang, Yulong Zhao, Xiaohui Chen, Jiajie Sun, Yang Zhou, Jianjin Wang, Yongan Wang, Xianyong Lan, Hong Chen*. (2014) Identification and Profiling of microRNAs and Their Target Genes from Developing Caprine Skeletal Muscle. PLoS ONE ,2014,9(5): e96857.

  Liangzhi Zhang, Mingjuan Yang, Congjun Li, Yao Xu, Jiajie Sun, Chuzhao Lei, Xianyong Lan, Chunlei Zhang, Hong Chen*. Identification and genetic effect of a variable duplication in the promoter region of the cattle ADIPOQ gene. Animal Genetics ,2014,45(2):171-179.

  Y. Zhou, H. Cai, Y. Xu, J. Sun, X. Lan, C. Lei and H. Chen*. Novel isoforms of the bovine Nuclear factor I/X (CCAAT-binding transcription factor) transcript products and their diverse expression profiles. Animal Genetics , 2014,45, 581–584.

  Mingxun Li, Xiaomei Sun, Jing Jiang, Yujia Sun, Xianyong Lan, Chuzhao Lei, Chunlei Zhang and Hong Chen*. Tetra-primer ARMS–PCR is an efficient SNP genotyping method: with an example from SIRT2. Analytical methods , 2014, 6:1835.

  Yong-Zhen Huang,Zhao-Yang Zhan,Yu-JiaSun,Xiu-Kai Cao,Ming-XunLi,Jing Wang,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,HongChen*.Intragenic DNA methylation status down-regulates bovine IGF2 gene expression in different developmental stages. Gene ,2014,534:356-361.

  Mei Liu, Mijie Li, Shaoqiang Wang, Yao Xu, Xianyong Lan, Zhuanjian Li, Chuzhao Lei, Dongying Yang, Yutang Jia,Hong Chen*. Association analysis of bovine Foxa2 gene single sequence variant and haplotype combinations with growth traits in Chinese cattle.  Gene ,2014, 536(2):385–392.

  Yao Xu,Tao Shi,Hanfang Cai,Yang Zhou,Xianyong Lan,Chunlei Zhang,Chuzhao Lei,Xinglei Qi,Hong Chen*. Associations of MYH3 gene copy number variations with transcriptional expression and growth traits in Chinese cattle. Gene ,2014, 535(2):106–111.

  Zi-nian Wang, Mi-jie Li, Xian-yong Lan, Ming-xun Li, Chu-zhao Lei, Hong Chen*. Tetra-primer ARMS-PCR identifies the novel genetic variations of bovine HNF-4 alpha gene associating with growth traits. Gene ,2014,546:206–213.(IF="2.082)

  Yonglong Dang, Mingxun Li, Mingjuan Yang, Xiukai Cao, Xianyong Lan, Chuzhao Lei, Chunlei Zhang, Qing Lin, Hong Chen*. Identification of bovine NPC1 gene cSNPs and their effects on body size traits of Qinchuan cattle. Gene ,2014,540:153-160.

  Gang Ren, Yong-Zhen Huang, Tian-Bao Wei, Jun-Xia Liu, Xian-Yong Lan, Chu-ZhaoLei,Chun-Lei Zhang, Zhi-Ying Zhang, Xing-Lei Qi, Hong Chen*. Linkage disequilibrium and haplotype distribution of the bovine LHX4 gene in relation to growth. Gene ,2014, 538:354–360.

  Zhuan-jian LiWen-jiao GuoYa-dong TianRui-li HanYu-jia SunJing XueXian-yong LanHong Chen* . Characterisation of the genetic effects of the ADFP gene and its association with production traits in dairy goats. Gene ,2014, 538(2):244–250.

  2013年:

  Jiajie Sun, Mijie Li, Zhuanjian Li, Jing Xue, Xianyong Lan, Chunlei Zhang, Chuzhao Lei, Hong Chen*. Identification and profiling of conserved and novel microRNAs from Chinese Qinchuan bovine longissimus thoracis. BMC Genomics,  2013, 14: 42.

  Yong-Zhen Huang,Ming-Xun Li,Jing Wang,Zhao-Yang Zhan,Yu-Jia Sun,Jia-Jie Sun, Cong-Jun Li,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Hong Chen*. A 5′- Regulatory Region and Two Coding Region Polymorphisms Modulate Promoter Activity and Gene Expression of the Growth Suppressor Gene ZBED6 in Cattle.  PLoS ONE , 2013, 8(11): e79744.

  Ming-xun Li, Xiao-mei Sun, Liang-zhi Zhang, Jing Wang, Yong-zhen Huang,Yu-jia Sun. Shen-rong Hu, Hong Chen*. A novel -274 C > G polymorphism in bovine SIRT1 gene contributes to diminished promoter activity and increased body size. Animal Genetics ,2013, 44(5): 584-587.

  Yao Xu,Liangzhi Zhang,Tao Shi,Yang Zhou,Hanfang Cai,Xianyong Lan,Chunlei Zhang,Chuzhao Lei,Hong Chen*. Copy number variations of MICAL-L2shaping gene expression contribute to different phenotypes of cattle.  Mamm Genome ,2013,24:508–516.

  Hanfang Cai, Aimin Li, Xianyong Lan, Chuzhao Lei, Hong Chen*. Genetic variations of HGF gene and their effects on growth traits in Chinese cattle . Research in Veterinary Science , 2013, 95(2): 483-488.

  Wang AZhang YLi MLan XWang JChen H*. SNP identification in FBXO32 gene and their associations with growth traits in cattle.  Gene ,2013, 515(1): 181-186.

  Xiao-Mei Sun,Ming-Xun Li, Ai-Min Li, Xian-Yong Lan, Chu-Zhao Lei, Wei Ma, Liu-shuai Hua, Jing Wang, Shen-Rong Hu, Hong Chen*. Two novel intronic polymorphisms of bovine FGF21 gene are associated with body weight at 18 months in Chinese cattle. Livestock Science ,2013,155:23–29. (IF="1.249)

  Yong-Zhen Huang, Ke-Yi Wang, Hua He,Qing-Wu Shen, Chu-Zhao Lei, Xian-Yong Lan, Chun-Lei Zhang, and Hong Chen*. Haplotype distribution in the GLI3 gene and their associations with growth traits in cattle. Gene , 2013, 513(1):141–146.

  Yong-Zhen Huang,Jing Wang,Zhao-Yang Zhan,Xiu-Kai Cao,Yu-JiaSun,Xian-Yong Lan,Chu-ZhaoLei,Chun-Lei Zhang,Hong Chen*. Assessment of association between variants and haplotypes of the IGF2 gene in beef cattle. Gene, 2013,528:139-145.

  Yong-Zhen Huang,Hua He,Zhao-Yang Zhan,Yu-Jia Sun,Ming-Xun Li,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Hong Chen*. Relationship of polymorphisms within ZBED6 gene and growth traits in beef cattle.  Gene ,2013,526:107–111.

  Jing Xue, Yujia Sun, Wenjiao Guo, Ziqi Yang, Huibin Tian, Chunlei Zhang, Chuzhao Lei, Xianyong Lan, Hong Chen*. Haplotypes and effects on growth traits of bovineWnt7agene in Chinese Qinchuan cattle. Gene ,2013,524(2):241-245.

  Mingxun Li, Xiaomei Sun, Liushuai Hua, Xinsheng Lai, Xianyong Lan, Chuzhao Lei, Chunlei Zhang, Xinglei Qi,Hong Chen*. SIRT1 gene polymorphisms are associated with growth traits in Nanyang cattle. Molecular and Cellular Probes , 2013, 27(7-8): 215-220.

  Mingxun Li, Xiaomei Sun, Liushuai Hua, Yongzhen Huang, Jing Wang, Xiukai Cao, Zhaoyang Zhan, Xianyong Lan, Chunlei Zhang,Shanzhai Liu, Hong Chen*. Molecular characterization, alternative splicing and expression analysis of bovine DBC1. Gene ,2013,527(2): 689-693.

  Mingjuan Yang,Junhui Fu,Xianyong Lan,Yujia Sun,Chuzhao Lei,Chunlei Zhang,Hong Chen*. Effect of genetic variations within the SH2B2 gene on the growth of Chinese cattle. Gene ,2013,528:314–319.

  Yong-Zhen Huang,Xin-Lei Wang,Hua He,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Hong Chen*. Identification and genetic effect of haplotype in the bovine BMP7gene. Gene ,2013,532:281–287.

  Zhou, Yang, Li C, Cai Hanfang, Xu Yao, Lan Xianyong, Lei Chuzhao & Chen Hong*. Novel polymorphisms of the APOA2 gene and its promoter region affect body traits in cattle. Gene , 2013,531(2): 288-293.

  Xiu-Kai Cao,JingWang,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Xing-Lei Qi,Hong Chen*. Genetic variants in BMP8B gene are associated with growth traits in Chinese native cattle. Gene ,2013,532:108–113.

  Sun Y., Xue J., Guo W., Li M., Huang Y., Lan X., Lei C., Zhang C. and Chen H*. Haplotypes of bovine FoxO1 gene sequence variants and association with growth traits in Qinchuan cattle. Journal of Genetics, 2013,92, e8–e14.

  Gao Y, Liu D, Ma W, Li A, Lan X, Zhang C, Lei C and Chen H*. Two novel SNPs in the coding region of bovine VDR gene and their associations with growth traits. Journal of Genetics ,2013,92, e53–e59.

  2012年:

  Zhuanjian Li, Xianyong Lan, Wenjiao Guo, Jiajie Sun, Yongzhen Huang, Jing Wang, Tinghua Huang, Chuozhao Lei, Xingtang Fang, Hong Chen*. Comparative Transcriptome Profiling of Dairy Goat MicroRNAs from Dry Period and Peak Lactation Mammary Gland Tissues. PLoS ONE , 2012, 7(12): e52388.

  Mingjuan Yang, Lian Qu, Junxia Liu, Xianyong Lan, Liangzhi Zhang, Jing Wang, Chuzhao Lei, Hong Chen*. Polymorphisms and effects on growth traits of the SH2B1 gene in Chinese cattle. Livestock Science ,2012,143:283–288.

  Liushuai Hua, Mingxun Li, Xiaomei Sun, Jing Wang, Zhuanjian Li, Yao Xu, Shenrong Hu and Hong Chen*. A dual color fluorescent reporter system for the real time detection of promoter activity.   Biotechnology Letters , 2012,34 (5):823-830.

  Bao Zhang, Gaofeng Zhao, Xianyong Lan, Chuzhao Lei, Chunlei Zhang,Hong Chen*. Polymorphism in GHRH gene and its association with growth traits in Chinese native cattle. Research in Verterinary Science.  2012,92(2): 243-246.

  B. Zhang,F. Peñagaricano,H. Chen and H. Khatib. Novel transcripts and alternatively spliced genes are associated with early development in bovine embryos.  Animal, 2012,1-7.

  Z.J. Li,X.Y. Lan,J.J. Sun,J. Wang,Y.Z. Huang,W.J. Guo,B. Zhang,C.Z. Lei,C.L. Zhang,H. Chen*. Molecular characterization and haplotype combination of PrRP gene polymorphism and its association with production traits in Chinese native goats. Small Ruminant Research ,2012,105(1–3):69-78.

  Bao Zhang,Yi Kun Guo,Shengbin Li,Liang Zhi Zhang,Xian Yong Lan,Shen Rong Hu,Hong Chen*. Genotype and haplotype analysis of the AZGP1 gene in cattle. Molecular Biology Reports , 2012,39: 10475–10479.

  2011年:

  Li Zhang, Ai-Ling Zhang, Liang-Zhi Zhang, Qin Zhang, Chun-Lei Zhang, Xian-Yong Lan, Hong Chen*. Association analysis between variants in bovine NPY gene and growth traits in Nanyang cattle (Bos taurus). General and Comparative Endocrinology, 2011, 170: 189–192.

  Y. Z. Huang, H. He, J. Wang, Z. J. Li, X. Y. Lan, C. Z. Lei, E. P. Zhang, C. L. Zhang,J. Q. Wang,Q. W. Shen and H. Chen*. Sequence variants in the bovine nucleophosmin 1 gene, their linkage and their associations with body weight in native cattle breeds in China. Animal Genetics, 2 011, 42, 556–559 .

  Bao Zhang, Ya Zhang, Liangzhi Zhang, Jing Wang, Zhuanjian Li and Hong Chen*. Allelic Polymorphism Detected in the Bovine FTO Gene. Molecular Biotechnology, 2011, 49(3): 257-262.

  Zhang Q, Zhao S, Chen H*, Zhang L, Zhang L, Li F, Wang X. SNP discovery and haplotype analysis in the bovine PRKAA2 gene. Molecular Biology Reports ,  2011, 38(3):1551-1556.

  C.L. Zhang,Y.H. Wang,H. Chen*,C.Z. Lei,X.T. Fang. The polymorphisms of bovine melanocortin-3 receptor pseudogene. Research in Veterinary Science , 2011, 90: 241-244.

  Shan Wang,Xin Cai,Kai Xue,Hong Chen*. Polymorphisms of MRF4 and H-FABP genes association with growth traits in Qinchuan cattle and related hybrids. Molecular Biology Reports ,  2011, 38: 1013–1020.

  C. Z. Lei, C. M. Zhang, S. Weining, M. G. Campana, M. A. Bower, X. M. Zhang, L. Liu,X. Y. Lan and H. Chen*. Genetic diversity of mitochondrial cytochrome b gene in Chinese native buffalo. Animal Genetics,  2011,42, 432–436.

  2010年:

  Ai-ling Zhang,Li Zhang,Liang-zhi Zhang,Hong Chen*,Xian-yong Lan,Chun-lei Zhang,Cun-fang Zhang. An efficient and rapid method for gene cloning from eukaryotic genomic DNA using overlap-PCR: With an example of cattle Ghrelin gene. Biochemical and Biophysical Research Communications, 2010, 391: 1490-1493.

  Shan Wang, Chunyan Tian, Tingtiang Xiao, Guichun Xing, Fuchu He, Lingqiang Zhang, Hong Chen*. Differential regulation of Apak by various DNA damage signals. Mol Cell Biochem,  2010, 333:181-187.

  X. Cai, H. Chen*, C. Lei. Matrilineal genetic inter-introgression of Bos taurus and Bos indicus in China. Livestock Science,  2010, 128: 12–19.

  Chuanying Pan,Baisong Lu,Hong Chen*,Colin E. Bishop*. Reprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC . Mol Biol Rep , 2010, 37: 2117–2124.

  Han, R.L., Lan, X.Y., Zhang, L.Z., Ren, G., Jing, Y.J., Li, M.J., Zhang, B., Zhao, M., Guo, Y.K., Kang, X.T., Chen, H*. A novel single-nucleotide polymorphism of the visfatin gene and its associations with performance traits in the chicken.  J Appl Genet, 2010,51, 59-65.

  Shangang Jia,Yan Zhou,Chuzhao Lei,Xiuqing Zhang,Ru Yao,Zhiying Zhang,Xingtang Fang,Hong Chen*. A new insight into cattle's maternal origin in six Asian countries.  Journal of Genetics and Genomics, 2010, 37: 173-180.

  Chuanying Pan, Amy Hicks, Hong Chen*, Colin E. Bishop*. SNL fibroblast feeder layers support derivation and maintenance of human induced pluripotent stem cells. J ournal of Genetics and Genomics ,2010, 37: 241−248.

  Pan C, Lan X, Chen H*, Bishop CE. An economical single-sided antibody incubation method for Western blotting. J Virol Methods ,2010,169(2): 409-11.

  2009年:

  C. Z. Lei, R. Su, M. A. Bower, C. J. Edwards, X. B. Wang, S. Weining,L. Liu, W. M. Xie, F. Li, R. Y. Liu, Y. S. Zhang, C. M. Zhang and H. Chen*. Multiple maternal origins of native modern and ancient horse populations in China. Animal Genetics , 2009,40, 933–944.

  ChunLei Zhang, YanHong Wang, Hong Chen*, ChuanWen Gu, XingTang Fang. SLC11A1 gene polymorphisms are not associated to somatic cell score and milk yield in Chinese Holstein. Veterinary Immunology and Immunopathology ,2009,127:389–392.

  Bifang Hao,Jinshan Huang,Xiulian Sun,Fei Deng,Yanfang Zhang,Hualin Wang, Hong Chen* and Zhihong Hu*. Variants of open reading frame Bm126 in wild-type Bombyx mori nucleopolyhedrovirus isolates exhibit functional differences.  Journal of General Virology, 2009, 90: 153-161.

  X.Y. Lan, C.Y. Pan, J.Y. Li, Y.W. Guo, S. Hu, J. Wang, Y.B. Liu, S.R. Hu, C.Z. Lei, H. Chen*. Twelve novel SNPs of the goat POU1F1 gene and their associations with cashmere traits. Small Ruminant Research ,2009, 85:116-121.

  Qin Zhang,Hong Chen*,Sheng Zhao,Li Zhang,Liangzhi Zhang,Fei Li,Xueming Wang. Single Nucleotide Polymorphisms and Haplotypic Diversity in the Bovine PRKAB1 Gene. Mol Biotechnol, 2009,43:193–199.

  2008年以前:

  C. Z. Lei, W. Zhang , H. Chen*, F. Lu, R. Y. Liu , X. Y. Yang, H. C. Zhang , Z. G. Liu, L. B. Yao, Z. F. Lu and Z. L. Zhao. Independent maternal origin of Chinese swamp buffalo (Bubalus bubalis), Animal Genetics ,2007,38(2): 97-102.

  M. Zhao, X. Wang, H. Chen*, X.Y. Lan, Y.K. Guo, J.Y. Li, T.B. Wei, Y.J. Jing, S.Q. Liu, M.H. Zhang, Q.W. Gao. The PCR-SSCP and DNA sequencing methods detecting a large deletion mutation at KAP6.2 locus in the cashmere goat. Small Ruminant Research ,2008,75:243–246.

  C.L. Zhang, H. Chen*, Y.H. Wang, R. F. Zhang, X.Y. Lan, C.Z. Lei, L. Zhang, A.L. Zhang, and S.R. Hu. Association of a Missence Mutation in Serotonin Receptor 1B (HTR1B) Gene with Milk Production Traits. Research in Veterinary Science, 2008,85:265-268.

  Chunlei Zhang, Hong Chen*, Yanhong Wang, Xianyong Lan, Chuzhao Lei, Xingtang Fang. The polymorphisms of bovine CART gene and their associations with cattle growth traits. Journal of Biosciences, 2008,33:365–370.

  M.J. Li, X.Y. Lan, H. Chen*, L.Z. Zhang, Y.J. Jing, G. Ren, T.B. Wei, X. Wang. The novel missense mutation of goat LHX4 gene,  Small Ruminant Research ,2008,79:109–112.

  Weibin SUN,Hong CHEN*,Chuzhao LEI,Xueqin LEI,Yinghan ZHANG. Genetic variation in eight Chinese cattle breeds based on the analysis of microsatellite markers。 Genetics Selection Evolution ,2008,40:681–692。

  H. Yu,X. Wang,H. Chen*,M. Wang,M. Zhao,X.Y. Lan,C.Z. Lei, K.Y.Wang,X.S. Lai,X.L.Wang. The polymorphism of a novel 30 bp-deletion mutation at KAP9.2 locus in the cashmere goat. Small Ruminant Research, 2008,80:111–115.

  CHEN Hong*, CAI Xin, LEIChu-zhao, FANG Xing-tang, ZHU Bi-cai,ZHANG Bao. Bos tauraus and Bos indicus: the Main Ancestress of Cattle Breeds in China Revealed by mtDNA Diversity(Abstract).  Cell Research , 2006,16: S109.

  Xin Cai,Hong Chen*,Chuzhao Lei,Shan Wang,Kai Xue,Bao Zhang. mtDNA diversity and genetic lineages of eighteen cattle breeds from Bos taurus and Bos indicus in China. Genetica,  2007,131: 175–183.

  ChunLei Zhang, Yanhong Wang, Hong Chen*, Xianyong Lan and Chuzhao Lei,. Enhance the Efficiency of Single-Strand Conformation Polymorphism Analysis by short Polyacrylamide Gel and Quick Low-Background Silver Staining. Analytical Biochemistry, 2007, 365:286–287.

  X. Wang, Y.H. Ma, H. Chen* and W.J. Guan. Genetic and phylogenetic studies of Chinese native sheep breeds (Ovis aries) based on mtDNA D-loop sequences.  Small Ruminant Research,  2007, 72:232-236.

  X. Y. Lan, C. Y. Pan, H. Chen*, and C. Z. Lei. A DdeI PCR-RFLP detecting genetic variation of goat POU1F1 gene. Canadian Journal of Animal Science , 2007, 87(1):13-14.

  X.Y. Lan, C.Y. Pan, H. Chen*, C.L. Zhang, J.Y. Li, M. Zhao, C.Z. Lei, A.L. Zhang, L. Zhang. An AluI PCR-RFLP detecting a silent allele at the goat POU1F1 locus and its association with production traits. Small Ruminant Research, 2007,73:8–12.

  X.Y. Lan, C.Y. Pan , H. Chen*, C.Z. Lei, S.Q. Liu,Y.B. Zhang, L.J. Min, J. Yu, J.Y. Li, M. Zhao, S.R. Hu. The HaeIII and XspI PCR-RFLPs detecting polymorphisms at the goat IGFBP-3 locus. Small Ruminant Research, 2007,73:283–286.

  Ai-Ling Zhang, Hui Liu, Ming-Ming Yang, Yue-Sheng Gong, Hong Chen. Assay and characterization of a strong promoter element from B. subtilis.  Biochemical and Biophysical Research Communications. 2007,354(1): 90-95.

  Shangang Jia, Hong Chen*, Guixiang Zhang, Zhigang Wang, Chuzhao Lei, Ru Yao, Xu Han. Genetic Variation of Mitochondrial D-loop Region and Evolution Analysis in Some Chinese Cattle Breeds. Journal of Genetics and Genomics, 2007,34(6): 510-518.

  YANG Dong-ying,CHEN Hong*,ZHANG ZHeng-feng,LAN Xian-yong,ZHANG Liang-zhi,HU Shen-rong,SU Li-hong,WANG Xin-zhuang,WANG Ju-qiang. Single Nucleotide Conformation Polymorphisms of Leptin Gene in Chinese Cattle.  Journal of Genetics and Genomics ,2007 34(5):400-405.

  Weibin Sun,Hong Chen*,Chuzhao Lei, Xueqin Lei,Yinghan Zhang. Study on Population Genetic Characteristics of Qinchuan Cows Using Microsatellite Markers.  Journal of genetics and Genomics, 2007, 34(1):17-25.

  Xin Cai, Hong Chen*, Shan Wang, Kai Xue, Chuzhao Lei. Polymorphisms of a Y Chromosome Specific Microsatellite in Chinese Cattle Breeds. Genetics Selection Evolution ,2006,38:525-534 .

  C. Z. Lei, H. Chen*, H. C. Zhang, X. Cai, R. Y. Liu, L. Y. Luo, C. F. Wang, W. Zhang, Q. L. Ge, R. F. Zhang, X. Y. Lan and W. B. Sun. Origin and phylogeographical structure of Chinese cattle. Animal Genetics , 2006, 37: 579–582.

  XUE Kai, CHEN Hong*, WANG Shan,CAI Xin, LIU Bo, ZHANG Cun-fang1 LEI Chu-zhao, WANG Xin-zhuang, WANG Yi-min, NIU Hui. Effect of Genetic Variations of POU1F1 Gene on Growth Traits of Nanyang Cattle.   Acta Genetica Sinica , 2006,  33 (10):901–907.

  WANG Xin, MA Yue-hui, CHEN Hong*. Analysis of the genetic Diversity and Phylogenetic Evolution of Chinese Sheep Based on Cyt b Gene Sequences. A cta Genetica Sinica,  2006,  33 (12):1081–1086.

  6. 论著与教材情况

  主  编:基因工程实验技术(全国高等农林院校十二五规划教材). 中国农业出版社,2015.8..

  主  编:基因工程(十一五规划教材),中国农业出版社,2011.6.

  主  编:基因工程实验技术(面向21世纪课程教材). 中国农业出版社,2005.

  主  编:基因工程原理与应用(面向21世纪课程教材). 中国农业出版社,2004.

  副主编:中国黄牛学. 中国农业出版社,2013.12.

  副主编:动物分子生物学. 高等教育出版社,2010.12

  副主编:动物遗传资源学. 科学出版社,2009.1.

  副主编:新编遗传学教程(面向21世纪课程教材). 中国农业大学出版社,2002.

  参  编:动物遗传学(第三版),中国农业出版社,2011,6.

  参 编:《动物种业科技创新战略研究报告》,科学出版社,2015年6月,参编,

  参  编:动物遗传学(面向21世纪课程教材). 中国农业出版社,2002.

  参  编:现代生物技术概论(面向21世纪课程教材).中国农业出版社,2003.

  参  编:国外畜禽生产新技术. 中国农业大学出版社,2003.

  主  编:Animal Biotechnology Bulletin(第八次全国畜禽遗传标记研讨会论文集), The Regional Coordinating Centre, The Asian Network for Biotechnology in Animal Production & Health (ANBAPH),  北京:2002年10月。(65万字)

  主  编:动物遗传育种学(成人教育畜牧兽医本科用),西北农林科技大学出版,2003年10月。

  主  编: Animal Biotechnology Bulletin(首届全国动物生物技术学分会学术研讨会论文集), The Regional Coordinating Centre, The Asian Network for Biotechnology in Animal Production & Health (ANBAPH),  北京:2004年5月。(140万字)

  主  编:中国牛业科技发展论坛,中国畜牧兽医学会养牛学分会2007年学术研讨会论文集,西北农林科技大学印,2007年7月。

  副主编:中国动物遗传育种研究进展,第十五次全国动物遗传育种学术讨论会论文集,2009年10月10-14,中国,杨凌.

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  “中国主要牛种经济性状分子遗传研究”2008年4月已通过教育部组织的成果鉴定(排名第一).

  “南阳牛肉用性状的分子育种关键技术研究”2008年12月通过河南省科技厅组织的成果鉴定(排名第一).

  《基因工程》2015年获陕西省优秀教材奖.(排名第一).

  

  联系方式:

  通讯地址:陕西杨凌西农路22号 西北农林科技大学动物科技学院

  邮编:712100

  联系电话:029-87092102(办)

  Email: chenhong1212@126.com, chenhong1212@263.net

  

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