Huiling Zheng

　　 　　

　　Department of Animal Sciences; College of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100,China

　　E-mail: zhenghuiling@nwsuaf.edu.cn

Education and Academic Experience:

2000-2004 Ph.D., Northwest A & F University, Animal Breeding and Genetics

1994-1997 M.Sc., Northwest Agriculture University, Animal Breeding and Genetics

1987-1991 B.Sc., Northwest Agriculture University , Animal science

8.2012-11.2012 Visiting scholar, Wageningen UR,Netherlands

4.2008-5.2008 Visiting scholar, Wageningen UR, Netherlands

4.2006-4.2007 Visiting scholar, Yale University Medical School,USA

9.2002-5.2004 Completed research work of PhD thesis in Tsinghua University Institute of Medical Research.

Professional and Expertise:

Member of Chinese Association of Animal & Veterinary Sciences

Member of Genetics and Breeding branch of Chinese Association of Animal & Veterinary Sciences

Member of Chinese Society for Cell Biology

Member of the Society for Cell Biology of shaanxi province

Research Interests:

Ø Physiology and regulation of mammary lactation

Ø Analysis on genetic basis of important economic traits of livestock and functional validation of key genes

Ø Principles and methods of animal breeding

Teaching:

l  Biostatistics ，  Research methods and scientific paper writing  for undergraduate  

l  Experimental Design and Data Statistical Analysis，  Proteomics  for postgraduate

Mainly published papers in English （*: Corresponding author)

1 Zhang, ZF，Tian, HB， Chen, XY ，Zhao, HY， Du, W ， Gao, HJ ，Luo, J ，Zheng, HL*. CRISPR/Cas9-mediated tryptophan hydroxylase 1 knockout decreases calcium transportation in goat mammary epithelial cells, Biochemical engineering journal， 2021（171）, 108015,1369-703X

2 Haiying Zhao, Shunxin Chen, Kaizhao Hu, Zhifei Zhang, Xiaoru Yan, Huijie Gao, Wei Du, Huiling Zheng*. 5-HTP decreases goat mammary epithelial cells apoptosis through MAPK/ ERK/Bcl-3 pathway. Gene, 2021 (769) 145240

3 Chen, Shunxin; Zhao, Haiying; Yan, Xiaoru; Zhang, Zhifei; Hu, Kaizhao; Gao, Huijie; Du, Wei; Luo, Jun; Zheng, Huiling*. 5-Hydroxy-l-tryptophan Promotes the Milk Calcium Level via the miR-99a-3p/ATP2B1 Axis in Goat Mammary Epithelial Cells. Journal of agricultural and food chemistry，2020(68)10, 3277-3285

4 W. J. Zang, H. Li, Z. F. Zhang, R. QuZhen, Y. Z. CuoMu, D. K. Zhang, J. Luo, J. J. Loor, and H. L. Zheng*. Serotonin induces parathyroid hormone-related protein in goat mammary gland.  Journal of animal science，2018，96（3），1010-1016

5 Hui Li, Huiling Zheng*, Lihui Li, Xingai Shen, Wenjuan Zang, Yongsen Sun, The Effects of Matrix Metalloproteinase-9 on Dairy Goat Mastitis and Cell Survival of Goat Mammary Epithelial Cells. PLoS ONE, 2016.8, 11(8): e0160989.

6 Hui Li  Lihui Li Wenjuan Zang  Huiling Zheng*.The Role of ΔFosB on the Pro-survival Effect of PTHrP in Goat Mammary Epithelial Cells, Journal of Applied Biochemistry and Biotechnology, 2016.10, 180（4）: 707-716.  

7 Hui Li  Lihui Li  Huiling Zheng*，Xiaotong Yao  Wenjuan Zang. Regulatory effects of ΔFosB on proliferation and apoptosis of MCF-7 breast cancer cells Tumor Biol. 2016.5, 37（5）: 6053-6063.

8 Hui Li, Yongsen Sun, Huiling Zheng*, Lihui Li, Qian Yu, Xiaotong Yao. Parathyroid hormone-related protein overexpression protects goat mammary gland epithelial cells from calcium-sensing receptor activation-induced apoptosis. Molecular Biology Reports. 2015.1，42(1): 233-243.  

9 Huiling Zheng*, Hui Li, Lihui Li, Shaoyang Ma, Xuemei Liu. ΔFosB regulates Ca2+ release and proliferation of goat mammary epithelial cells. Gene, 2014, 545(2): 241–246.

10  Hui Li, Huiling Zheng*, Yongsen Sun, Qian Yu, Lihui Li. Signal transducer and activator of transcription 5a inhibited by pimozide may regulate survival of the goat mammary gland epithelial cells by regulating parathyroid hormone-related protein. Gene, 2014，551 (2): 279–289.  

11  H.L. Zheng*, H. Li, Z.Y. Yang, Q. Yu.Parathyroid hormone-related peptide (PTHrP): prokaryotic expression, purification and preparation of a polyclonal antibody. Genetics and Molecular Research,2014, 13 (3): 6448-6454

12  H.L. Zheng*, X.M. Liu, Q. Yu, R.F. Xing, Z.Y. Yang and J. Luo. Construction of recombinant adenoviruses carrying the optimal shRNA template against goat PTHrP and successful suppression of PTHrP expression in mammary epithelial cells. Genetics and Molecular Research, 2013,12 (3): 3363-3374

13  Xueni Li△, Mei Huang△, Huiling Zheng△ Yinyin Wang, Fangli Ren, Yu Shang, Yonggong Zhai, Di Chen, David M. Irwin, Yuguang Shi, and Zhijie Chang*. CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation. The Journal of Cell Biology  2008  181（6）： 959-972  （△: Author with equal contribution）