Xiaoteng Fan

　　 　　

Education and Training

Northwest A&F University, BS, Animal Science, 2014

Northwest A&F University, MS, Animal Cultivation, 2016

Northwest A&F University, PhD, Hydrobiology, 2020

Biosketch

Dr. Fan jointed College of Animal Science and Technology, Northwest A&F University as an associated professor in 2020 and as a member of Aquatic Ecology and Environment Restoration Team in Department of Aquatic Science. His current research centers on the following foci:

Epigenetic mechanisms on development and reproduction of fish under environmental stress.

Zebrafish and cell line as models of environmental contaminants evaluation.

Determination and risk assessment of heavy metals, pesticides, antibiotics, and other pollutants in rivers and lakes.

Research Keywords

Environmental epigenetics; DNA methylation; Stress response; Zebrafish; Cell culture; Toxicology; Fish mitochondrial dynamics; Aquatic ecology.

Highlighted Publications

Fan X, Wang L, Wei X, Zhang J, Su X, Cui L, Wang Z. The impairment of continuous malnutrition on larval fish swimming performance at the mouth-opening stage. Aquaculture. 2021 November; 544: 737053.

Fan X, Cui L, Hou T, Xue X, Zhang S, Wang Z. Stress responses of testicular development, inflammatory and apoptotic activities in male zebrafish (Danio rerio) under starvation. Dev Comp Immunol. 2021 Jan;114:103833. doi: 10.1016/j.dci.2020.103833.

Fan, X., Hou, T., Guan, Y., Li, X., Zhang, S., Wang, Z., 2020. Genomic responses of DNA methylation and transcript profiles in zebrafish cells upon nutrient deprivation stress. Sci Total Environ. 722, 137980. 10.1016/j.scitotenv.2020.137980.

Fan, X., Hou, T., Sun, T., Zhu, L., Zhang, S., Tang, K., Wang, Z., 2019a. Starvation stress affects the maternal development and larval fitness in zebrafish (Danio rerio). Sci Total Environ. 695, 133897. 10.1016/j.scitotenv.2019.133897.

Fan, X., Hou, T., Jia, J., Tang, K., Wei, X., Wang, Z., 2020. Discrepant dose responses of bisphenol A on oxidative stress and DNA methylation in grass carp ovary cells. Chemosphere. 248, 126110. 10.1016/j.chemosphere.2020.126110.

Fan, X., Hou, T., Zhang, S., Guan, Y., Jia, J., Wang, Z., 2019b. The cellular responses of autophagy, apoptosis, and 5-methylcytosine level in zebrafish cells upon nutrient deprivation stress. Chemosphere. 241, 124989. 10.1016/j.chemosphere.2019.124989.

Fan, X., Wu, L., Hou, T., He, J., Wang, C., Liu, Y., Wang, Z., 2018. Maternal Bisphenol A exposure impaired endochondral ossification in craniofacial cartilage of rare minnow (Gobiocypris rarus) offspring. Ecotoxicol Environ Saf. 163, 514-520. 10.1016/j.ecoenv.2018.07.100.

Sun L.#, Fan X.#, Zeng Y., Wang, L., Zhu, Z., Li, R., Tian, X., Wang, Y., Lin, Y., Wu, D., & Zeng, W. 2020. Resveratrol protects boar sperm in vitro via its antioxidant capacity, Zygote. 2020;1-8. doi:10.1017/S0967199420000271.

Jia J, Guan Y, Li X, Fan X, Zhu Z, Xing H, Wang Z. Phenotype profiles and adaptive preference of Acinetobacter johnsonii isolated from Ba River with different environmental backgrounds. Environ Res. 2021 May;196:110913. doi: 10.1016/j.envres.2021.110913.

Zhu L, Wang L, Fan X, Dong C, Wang G, Wang Z. Chronic exposure to Bisphenol A resulted in alterations of reproductive functions via immune defense, oxidative damage and disruption DNA/histone methylation in male rare minnow Gobiocypris rarus. Aquat Toxicol. 2021 Jul;236:105849.

Zhu, Z., Li, R., Fan, X., Lv, Y., Zheng, Y., Hoque, S. A. M., Wu, Zeng, W., 2019. Resveratrol Improves Boar Sperm Quality via 5'AMP-Activated Protein Kinase Activation during Cryopreservation. Oxid Med Cell Longev. 2019, 5921503. 10.1155/2019/5921503.

Zhang, Y., Guan, Y., Fan, X., Wu, L., Wang, Z., 2018. Bisphenol A regulates rare minnow testicular vitellogenin expression via reducing its promoter Er recruitment. Ecotoxicol Environ Saf. 147, 423-429. 10.1016/j.ecoenv.2017.09.001.

Zhu, Z., Li, R., Ma, G., Bai, W., Fan, X., Lv, Y., Luo, J., Zeng, W., 2018. 5'-AMP-Activated Protein Kinase Regulates Goat Sperm Functions via Energy Metabolism In Vitro. Cell Physiol Biochem. 47, 2420-2431. 10.1159/000491616.

Liu, T., Chen, X., Li, T., Li, X., Lyu, Y., Fan, X., Zhang, P., Zeng, W., 2017. Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway. Biochim Biophys Acta Gene Regul Mech. 1860, 1094-1102. 10.1016/j.bbagrm.2017.08.009.

Zhu, Z., Fan, X., Lv, Y., Lin, Y., Wu, Zeng, W., 2017a. Glutamine protects rabbit spermatozoa against oxidative stress via glutathione synthesis during cryopreservation. Reprod Fertil Dev. 29, 2183-2194.

Zhu, Z., Fan, X., Pan, Y., Lu, Y., Zeng, W., 2017b. Trehalose improves rabbit sperm quality during cryopreservation. Cryobiology. 75, 45-51. 10.1016/j.cryobiol.2017.02.006.

Zhu, Z., Ren, Z., Fan, X., Pan, Y., Lv, S., Pan, C., Lei, A., Zeng, W., 2017c. Cysteine protects rabbit spermatozoa against reactive oxygen species-induced damages. PLoS One. 12, e0181110.

Zhu, Z., Fan, X., Lv, Y., Zhang, N., Fan, C., Zhang, P., Zeng, W., 2015. Vitamin E Analogue Improves Rabbit Sperm Quality during the Process of Cryopreservation through Its Antioxidative Action. PLoS One. 10, e0145383. 10.1371/journal.pone.0145383.

Contact

Address: College of Animal Science and Technology, Northwest A&F University, No. 22, Xinong Road, Yangling, Shaanxi Province, 712100, China.

E-mail: fanxiaoteng@nwafu.edu.cn