Chen Hong

  Dr. Hong CHEN, Professor

  


 

  Head of Department

  

  Northwest A&F University

  College of Animal Sciences and Technology

  Department of Animal Sciences

  

  Xinong Road No.22

  Yangling, Shaanxi, 712100

  P. R. China

  Telephone: ++86-29-87092102

  Fax:      ++86-29-87092164

  E-mail:    chenhong1212@263.net

  chenhong1212@126.com

  

  


 

  Curriculum Vitae

  

  Name:       CHEN Hong

  Sex :        Male

  Dateof birth:  December 12. 1955(Gregorian Calendar)

  October 29.1955(Chinese Calendar).

  Place of birth: Xi’an, Shaanxi, P. R. China

  Education and Academic Experience:

  Postdoc, Friedrich-Schiller-University Jena, Germany, May 1996 - Aug. 1998

  PhD.  in Genetics, University of Saarland, Germany, Aug. 1992 - Apr. 1996

  M.Sc. in Animal Breeding and Genetics, Northwest Agricultural University, Sep.1987- Sep.1990

  B.Sc.  in Animal Science, Northwest Agricultural University, Feb. 1978 - Dec. 1981

  

  Professional and Expertise Positions

  

  Scientific Member, Academic Division of Life Sciences, Science and Technology Committee of Ministry of Education in China

  Deputy member of Council, Chinese Society for Cell Biology

  Vice Chairman, Branch of Genetic Markers of Domestic Animals and Poultry, Chinese Association of Animal Science and Veterinary Medicine

  Vice Chairman, Branch of Cattle Science, Chinese Association of Animal Science and Veterinary Medicine

  Member of Council, Branch of Animal Genetics and Breeding, Chinese Association of Animal Science and Veterinary Medicine

  Member of Council,  China Cattle Industry Association

  Deputy Member and V ice -secretary-general, Committee of Chinese Yellow Cattle Breeding

  Deputy Member of Council, Branch of Animal Biotechnology, China Agricultural Biotechnology Association

  Vice Chairman, Shaanxi Society for Genetics

  Vice Chairman, Shaanxi Society for Cell Biology

  Vice Chairman, Shaanxi Society for Biochemistry and Molecular Biology

  

  Editor-in-Chief, 《China Cattle Science》

  Editorial Board, 《Hereditas (Beijing)》

  Editorial Board, 《Progress in Modern Biomedicine》

  Editorial Board, 《Journal of Clinical Rehabilitative Tissue Engineering Research》

  Editorial Board, 《China Herbivores》

  Editorial Board, 《Journal of Northwest A & F University (Natural Science Edition)》

  Director, Division of Animal Section, Shaanxi Key Laboratory of Molecular Biology for Agriculture

  Vice Director, Biotechnology Centre, Northwest A & F University

  Research fields

  Breeding and Biotechnology

  Molecular Genetics and Genomics

  Genetic Resources and Application

  Research Interests:

  My research interests are on modern animal breeding by means of molecular biotechnology especially in bovine and goat, and genetic variations related to economic traits in livestock or natural variations in wild species. Furthermore, genetic resources investigations in domestic and wild animal species are also part of our work. A primary focus is identification of function genes (quantitative trait loci, QTL) contributing to variation in bovine growth and meat quality traits. Use of markers linked with economic traits in selection programs will greatly facilitate increasing growth and meat quality traits. Comparative genomic approach in livestock will provide DNA data for selection.

  Teaching:

  Molecular Genetics: Spring, 1999 to present, for Postgraduate

  Animal Genetics: Spring, 1983 to present, for student of Animal Science

  Introduction to Undergraduate Research, for student of Animal Science

  Gene Engineering: Fall, 2004 to 2008, for student of Bioscience

  Cytogenetic: Spring, Fall,1999 to present, for Postgraduate

  Lectures in Modern Biotechnology, Fall, 1999 to 2008, for PhD student

  Lectures in Animal Breeding and Genetics , Spring, 2008 to present, for PhD student

  Awards:

  Second-class Scientific Award of State Science and Technology Development in China(Germplasm Innovation of Nanyang cattle,new breed Cultivate of Xianan cattle and its Industrialization)in 2013.

  First-class Scientific Award of Science and Technology Development in Henan province (Conservation and Utilization of breed Resources of Nanyang Cattle)in 2016.

  First-class Scientific Award of Science and Technology Development in Shaanxi province (Important gene excavations, molecular marker development of economic traits and their breeding applications in Chinese cattle) in 2014.

  Second-class Scientific Award of Science and Technology Development in Ningxia province(Study on localization of QTL for resistance to cold in Guyuan chicken)in2013.

  Second-class Scientific Award of Science and Technology Development in Ningxia province(Development and Demonstration of efficient high-quality breeding and rearing techniques in Liupanshan beef cattle)in 2011.

  First-class Scientific Award of Science and Technology Development in Shaanxi province (study on genetic character of local yellow cattle breeds in Shaanxi) 2003

  First-class Scientific Award of Science and Technology Development for Universities in Shaanxi province. (Study on chromosome character of four local yellow cattle breeds in Shaanxi) 2001.

  Third-class Scientific Award of Science and Technology Development in Jiangsu province (study on molecular genetic character of production traits in Chinese Holstein) 2008

  Second-class Scientific Award of Excellence Treatise of Natural Science in Shaanxi province (Polymorphisms of two Y chromosome microsatellites in Chinese cattle) 2008

  Second-class Scientific Award of Excellence Treatise of Natural Science in Shaanxi province (The Effect of CSN1S2, CSN3 and β-1g Genes on Milk Performance in Xinong Saanen Dairy Goat) 2008

  First-class Scientific Award of Excellence Treatise of Natural Science in Shaanxi province (Study on Mitochondrial DNA Genetic Diversity of Some Cattle Breeds in China) 2006

  Second-class Scientific Publication Award of Excellence Treatise of Natural Science in Shaanxi province (Microsatellite Markers on Fecundity Trait of Small Tailed Han Sheep) 2006

  Third-class Scientific Award of Excellence Treatise of Natural Science in Shaanxi province Ag-NOR Polymorphism and Origin Evolution of Domestic Pigs) 1992

  Third-class Scientific Award of Excellence Treatise of Natural Science in Shaanxi province (Chromosome G banding pattern of cattle (Bos Taurus) of China) 2001

  Third-class Scientific Award of Excellence Treatise of Natural Science in Shaanxi province (Studies on Y Chromosome Polymorphism and the Origin and Classification of Chinese Yellow Cattle) 2001

  Excellence Textbook Award of Chinese high Agra-Forest Universities (Principle and Applications of Gene Engineering) 2006. (Editor-in-chief)

  Second-class Award of Excellence Textbook in Shaanxi province (Principle and Applications of Gene Engineering), 2008. (Editor-in-chief)

  Second-class Award of Excellence Teaching in Shaanxi province, 2002

  First -class Award of Excellence Teaching in Shaanxi province, 2008.

  National Excellence Course, Animal genetics, Ministry of Education, 2009

  Excellence Teaching Group of Shaanxi province in animal genetics, 2010.

  Patent: Chinese Patent No.ZL200710017973.6—a PCR-RFLP Method for Determining SNP of PRL gene in goat. Issued August 26, 2009.

  Research Projects:

  National Natural Science Foundation of China (No. 31772574): Regulation Mechanism of Circular RNA circMDs on the Proliferation and Differentiation of Bovine Myoblast Cells. Jan.2018-Dec.2021.

  National Modern Beef Cattle Industry Technology System Program(CARS-38) Jan.2011-Dec.2015.

  National Natural Science Foundation of China (No. 31272408): Identification of miRNA-related muscle development and their function Study in Qinchuan cattle. Jan.2013-Dec.2016.

  The National 863 (High-Tech) Program of China (No. 2013AA102505): Study on functional genomics of important economical traits in beef cattle of China. Jan.2013-Dec.2017.

  National Natural Science Foundation of China (No. 30972080): Screening and functional identification of copy number variation (CNV) of important function gene in Chinese Cattle. Jan.2010-Dec.2012.

  The National 863 (High-Tech) Program of China (No.2006AA10Z197): Studies on Molecular Markers and Identification of Key Functional Genes of Meat Production Traits in Qinchuan and Nanyang Cattle Breeds.Dec.2006-Dec.2010.

  National Key Technology R&D Program (No. 2006BAD01A10-5): Studies on Marker of Candidate Genes of Meat Production Traits in Cattle. Oct.2006-Dec.2010.

  National Natural Science Foundation of China (No. 30771544): Studies on Genetic Character of Important Energy Homeostasis Regular Genes and Their Network Relation. Jan.2008-Dec.2010.

  “13115” Sci-Tech Innovation Program of Shaanxi Province (2008ZDKG-11): Study and Application of Key Technique of Biotechnological Breeding in Cattle and Goat.  Jan.2009-Dec.2012.

  National Modern Beef Cattle Industry Technology System Program(Nycytx-38) Jan.2008-Dec.2010.

  Research Fund for the Doctor Program of Higher Education of China (No.20080712001): Molecular Character of PROP1-POU1F1 Regular Gene Family and Their Genetic Effect. Jan.2009-Dec.2011.

  National Transgene Major Project in China (2009ZX08009-157B): Branch Project of Cloning and Function Identification of Key Genes for Muscle Development and Fat Precipitation in cattle.Jan.2009-Dec.2010.

  National Transgene Major Project in China (2008ZX08007-002): Branch Project of Cloning, Leading-in, Identification, Expression of Important Function Genes about Meat Quality Traits in Cattle. Jan. 2008 - Dec.2010.

  National Key Technology R&D Program (No. 2008BADB2B03-19, Study on Molecular Technology of Selection of High Quality Beef Cattle. Jan.2008-Dec.2010.

  Publications:

  I have been listed as author or corresponding author of nearly 400 scientific articles throughout the world, of which more than 310 papers were included in the Science Citation Index (SCI). The following publications were selected from peer-reviewed journals within 5 years.

  NB:*: Corresponding author

  2019

  Xiu-Kai Cao#, Jie Cheng#, Yong-Zhen Huang#, Xiao-Gang Wang, Yu-Lin Ma, Shu-Jun Peng, Buren Chaogetu, Zhaxi Zhuoma, and Hong Chen*. Growth Performance and Meat Quality Evaluations in Three-Way Cross Cattle Developed for the Tibetan Plateau and their Molecular Understanding by Integrative Omics Analysis. Journal of Agricultural and Food Chemistry,2019, 67, 541−550.

  Jian WangChengchuang Song ,Xiukai CaoHui LiYilei MaYongzhen HuangXianyong LanChuzhao LeiYun MaYueyu BaiFengpeng Lin ,Hong Chen*. MiR‐208b regulates cell cycle and promotes skeletal muscle cell proliferation by targeting CDKN1A. Journal of Cellular Physiology,2019,234: 3720–3729.

  Wu Jiyao, Yue Binglin, Lan Xianyong, Wang Yanhuan, Fang Xingtang, Ma Yun, Bai Yueyu, Qi Xingshan, Zhang Chunlei*,Chen Hong*. MiR-499 regulates myoblast proliferation and differentiation by targeting transforming growth factor beta receptor 1. Journal of Cellular Physiology,2019, 234(3):2523-2536.

  Chengchuang Song, Zhaoxin Yang, Dong Dong, Jiawei Xu, Jian Wang, Hui Li, Yongzhen Huang, Xianyong Lan,Chuzhao Lei,Yun Ma,Hong Chen* miR-483 regulates cattle muscle cells growth and differentiation through IGF1/AKT signal pathway. Journal of Cellular Physiology , 2019,234(6): 9839-9848.

  Chengchuang Song#, Jiameng Yang#, Rui Jiang, Hui Li, Zhaoxin Yang, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Yun Ma, Xinglei Qi, Hong Chen*. Overexpression of miR-148a-3p regulates proliferation and apoptosis of bovine muscle cells by targeting KLF6. Journal of Cellular Physiology , 2019.1.13, Accepted: DOI: 10.1002/jcp.28232.

  Binglin Yue, Hui Li, Mei Liu, Mingxun Li, Jiyao Wu, Chuzhao Lei, Bizhi Huang, Hong Chen*. Characterization of lncRNA–miRNA–mRNA network to reveal potential functional ceRNAs in bovine skeletal muscle. Frontiers in Genetics,2019,2,Accepted.

  Mei Liu, Bo Li, Wenwen Peng, Yilei Ma, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, George E. Liu, Xinglei Qi,Hong Chen*. LncRNA-MEG3 promotes bovine myoblast differentiation by sponging miR-135. Journal of Cellular Physiology , 2019.2. Accepted.

  Mei Liu, Lingzhao Fang, Shuli Liu, Michael G. Pan, Eyal Seroussi, Li Ma, Hong Chen*, George E. Liu*. Array CGH based detection of CNV regions and their potential association with reproduction and other economic traits in Holsteins. BMC genomics, 2019.2. Accepted.

  2018年

  Hui Li#, Jiameng Yang#, Rui Jiang, Xuefeng Wei, Chengchuang Song, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Yun Ma, Linyong Hu, Hong Chen*. Long non-coding RNA profiling reveals an abundant MDNCR that promotes differentiation of myoblasts via sponging miR-133a. Molecular Therapy: Nucleic Acids, 2018, 12: 610-625.

  Hui Li#, Xuefeng Wei#, Jiameng Yang#, Dong Dong, Dan Hao, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Yun Ma, Fengpeng Lin, Yueyu Bai, and Hong Chen*. circFGFR4 Promotes Differentiation of Myoblastsvia Binding miR-107 to Relieve Its Inhibition of Wnt3a. Molecular Therapy: Nucleic Acids, 2018, 11: 272-283.

  Chengchuang Song#, Jian Wang#, Yilei Ma, Zhaoxin Yang, Dong Dong, HuiLi, Jiameng Yang, Yongzhen Huang, Martin Plath, Yun Ma & Hong Chen*. Linc-smad7promotes myoblast differentiation and muscle regeneration via sponging miR-125b. Epigenetics, 2018,13(6):591-604.

  Hui Li#, Jiameng Yang#, Xuefeng Wei#, Chengchuang Song, Dong Dong, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Yun Ma, Xinglei Qi, Yueyu Bai, Hong Chen*. CircFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a. Journal of Cellular Physiology, 2018, 233:4643–4651.

  Yuan‐Chao Sun, Yong‐Yong Wang, Xiao‐Feng Sun, Shun‐Feng Cheng, Lan Li, Yong Zhao, Wei Shen*, Hong Chen*. The role of autophagy during murine primordial follicle assembly. AGING, 2018, 10(2): 197-211. www.aging‐us.com.

  Hanfang Cai#, Mingxun Li#, Xiaomei Sun, Martin Plath, Cong-jun Li, Xianyong Lan, Chuzhao Lei, Yongzhen Huang, Yueyu Bai, Xinglei Qi, Fengpeng Lin and Hong Chen*“Global transcriptome analysis during adipogenic differentiation and involvement of transthyretin gene in adipogenesis in cattle”, Frontiers in Genetics. 2018,9:463.

  Yongzhen Huang, Xinsheng Lai, Linyong Hu, Chuzhao Lei, Xianyong Lan, Chunlei Zhang, Yun Ma, Li Zheng, Yue-Yu Bai, Fengpeng Lin, Hong Chen*. Over-expression of DEC1 inhibits myogenic differentiation by modulating MyoG activity in bovine satellite cell. Journal of Cellular Physiology,2018, 233(12):9365-9374.

  Yujia Sun, Kunpeng Liu, Yongzhen Huang, Xianyong Lan, Hong Chen*, Differential expression of FOXO1 during development and myoblast differentiation of Qinchuan cattle and its association analysis with growth traits. SCIENCE CHINA Life Sciences, 2018, 61(7): 826-835.

  Yao Xu, Tao Shi, Yang Zhou, Mei Liu, Sebastian Klaus, Xianyong Lan, Chuzhao Lei, Hong Chen*.A novel PAX7 10-bp indel variant modulates promoter activity, gene expression and contributes to different phenotypes of Chinese cattle. Scientific Reports, 2018, 8:1724.

  Xiu-Kai Cao, Yong-Zhen Huang, Yi-Le Ma, Jie Cheng, Zhen-Xian Qu, Yun Ma, Yue-Yu Bai, Feng Tian, Feng-Peng Lin, Yu-Lin Ma, Hong Chen*. Integrating CNVs into meta-QTL identified GBP4 as positional candidate for adult cattle stature. Functional & Integrative Genomics, 2018, 1-9.

  Xuefeng Wei#,Hui Li#,Guangwei ZhaoJiameng YangLihui LiYongzhen HuangXianyong LanYun MaLinyong HuHuiling ZhengHong Chen*. ΔFosB regulates rosiglitazone‐induced milk fat synthesis and cell survival。Journal of Cellular Physiology,2018,233(12):9284-9298.

  2017

  Xuefeng Wei, Hui Li, Jiameng Yang, Dan Hao, Dong Dong, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Fengpeng Lin, Yueyu Bai and Hong Chen*. Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p. Cell Death and Disease (2017) 8, e3153; doi:10.1038/cddis.2017.541; published online 26 October 2017

  Hui Li, Xuefeng Wei, Jiameng Yang, Dong Dong, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Xinglei Qi, Yueyu Bai and Hong Chen*. Developmental transcriptome profiling of bovine muscle tissue reveals an abundant GosB that regulates myoblast proliferation and apoptosis. Oncotarget, 2017, Vol. 8, (No. 19), pp: 32083-32100.

  Mingjuan Yang , Jingqiao Lv, Liangzhi Zhang, Mingxun Li, Yang Zhou, Xianyong Lan, Chuzhao Lei, Hong Chen*. Association study and expression analysis of CYP4A11 gene copy number variation in Chinese cattle. Scientific Reports, 2017, 7:46599. DOI: 10.1038/srep46599

  Zhuanjian Li, Xianyong Lan, Ruili Han*, Jing Wang, Yongzhen Huang, Jiajie Sun, Wenjiao Guo & Hong Chen*. miR-2478 inhibits TGFβ1 expression by targeting the transcriptional activation region downstream of the TGFβ1 promoter in dairy goats. Scientific Reports, 2017, 7: 42627. DOI: 10.1038/srep42627

  Mei Liu, Bo Li, Yongzhen Huang, Mingjuan Yang, Xianyong Lan, Chuzhao Lei, Weidong Qu, Yueyu Bai*, Hong Chen*. Copy number variation of bovine MAPK10 modulates the transcriptional activity and affects growth traits. Livestock Science, 2016, 194: 44–50.

  K.X. Cao, D.Hao, J.Wang, W.W. Peng, Y.J. Yan, H.X. Cao, F. Sun, H. Chen*. Cold exposure induces the acquisition of brown adipocyte gene expression profiles in cattle inguinal fat normalized with a new set of reference genes for qRT-PCR. Research in Veterinary Science 2017, 114: 1–5.

  Yao Xu, Yu Jiang, Tao Shi, Hanfang Cai, Xianyong Lan, Xin Zhao, Martin Plath, Hong Chen*. Whole-genome sequencing reveals mutational landscape underlying phenotypic differences between two widespread Chinese cattle breeds. PLoS ONE , 2017,12(8): e0183921.

  Yuan-Chao Sun, Xiao-Feng Sun, Paul W. Dyce, Wei Shen*, Hong Chen*. The role of germ cell loss during primordial follicle assembly: a review of current advances. International Journal of Biological Sciences,2017; 13(4): 449-457. doi: 10.7150/ijbs.18836

  Yan Hong Wang,Jun Qiang Liu,Hui Wu,Xing Tang Fang,Hong Chen*,Chun Lei Zhang*。Amino acids regulate mTOR pathway and milk protein synthesis in a mouse mammary epithelial cell line is partly mediated by T1R1/T1R3。European Journal of Nutrition , 2017, 56(8):2467–2474。

  Binglin Yue, Jiyao Wu, Yanhuan Wang, Chunlei Zhang, Xingtang Fang, and Hong Chen*. Expression Profiles Analysis and Functional Characterization of MicroRNA-660 in Skeletal Muscle Differentiation. Journal of Cellular Biochemistry, 2017 , 118:2387–239.

  2016

  Mingxun Li, Xiaomei Sun, Hanfang Cai, Yujia Sun ,Martin Plath, CongjunLi, Xianyong Lan,Chuzhao Lei, Fengpeng Lin, Yueyu Bai*, Hong Chen*. Long non-coding RNA ADNCR suppresses adipogenic differentiation by targeting miR-204. Biochimica et Biophysica Acta , 2016,1859:871–882. (IF="5.373)"

  Wei X, Li H, Zhang B, Li C, Dong D, Lan X, Huang Y, Bai Y, Zhao X, Chen H*.miR-378a-3p Promotes Differentiation and Inhibits Proliferation of Myoblasts by Targeting HDAC4 in Skeletal Muscle Development. RNA Biology, 2016, 13(12): 1300-1309.

  Mingxun Li,Xiaomei Sun,Yang Zhou,Xuefeng Wei,Yujia Sun,Xianyong Lan,Chuzhao Lei,Hong Chen*。Nicotinamide and resveratrol regulate bovine adipogenesis through a SIRT1-dependent mechanism. Journal of Functional Foods, 2015,18:492–500. (IF="3.973)

  Xiaomei Sun, Mingxun Li, Yujia Sun, HanfangCai, XianyongLan, Yongzhen Huang, YueyuBai, Xinglei Qi, Hong Chen*.  The developmental transcriptome sequencing of bovine skeletal muscle reveals a long noncoding RNA, lncMD, promotes muscle differentiation by sponging miR-125b.  Biochimica et BiophysicaActa (BBA)-Molecular Cell Research, 2016, 1863(11): 2835-2845. (IF="5.128)"

  X. Sun, M. Li, Y. Sun, H. Cai, R. Li, X. Wei, X. Lan, Y. Huang, C. Lei, and H. Chen*. The evelopmental transcriptome landscape of bovine skeletal muscle defined by Ribo-Zero ribonucleic acid sequencing. Journal of Animal Science , 2015, 93:5648–5658. (IF="2.108)"

  Yang Zhou,Lingyang Xu,DerekM. Bickhart,ElHamidiabdel Hay,StevenG. Schroeder,ErinE. Connor, LeesonJ. Alexander, TadS. Sonstegard, CurtisP. Van Tassell, Hong Chen*, and George E.Liu*. Reduced representation bisulphite sequencing of ten bovine somatic tissues reveals DNA methylation patterns and their impacts on gene expression. BMC Genomics,2016,17: 779.(IF="3.867)

  Lan Li,Jing-Cai Liu,Fang-Nong Lai,Huan-Qi Liu,Xi-Feng Zhang,Paul W. Dyce,Wei Shen,Hong Chen*. Di(2-ethylhexyl) Phthalate Exposure Impairs Growth of Antral Follicle in Mice. PLOS ONE, 2016, e.0148350(IF="3.057)

  Zhang, BW,Cai, HF,Wei, XF,Sun, JJ ,Lan, XY,Lei, CZ,Lin, FP,Qi, XL,Plath, M,Chen, H*. miR-30-5p Regulates Muscle Differentiation and Alternative Splicing of Muscle-Related Genes by Targeting MBNL. International journal of molecular sciences, 2016, 17(2): 182. (IF="3.257)

  Wang Y, Liu J, Wu H, Fang X, Chen H*, Zhang C*. Amino acids regulate mTOR pathway and milk protein synthesis in a mouse mammary epithelial cell line is partly mediated by T1R1/T1R3. Eur J Nutr. 2016 doi:10.1007/s00394-016-1282-1 (SCI 2区 IF2016= 3.239)

  

  2015年

  J. Wang, L.S. Hua, H. Pan, L.Z. Zhang, M.X. Li, Y.Z. Huang, X.Y. Lan, C.Z. Lei and H. Chen*. Haplotypes of cis-acting elements in CIDEC gene possessing different transcriptional activities associated with body weight and average daily gain. Scientific Reports. 2015,(5):720.(IF="5.578)

  Liangzhi Zhang; Shangang Jia; Martin Plath; Yongzhen Huang; Congjun Li; Chuzhao Lei; Xin Zhao; Hong Chen*. Impact of parental Bos taurus and Bos indicus origins on copy number variation in traditional Chinese cattle breeds. Genome Biology and Evolution,Genome Biol. Evol. 2015,7(8): 2352–2361.

  Lan Li, Jing-Cai Liu, Yong Zhao, Fang-Nong Lai, Fan Yang, Wei Ge, Cheng-Li Dou, Wei Shen, Xi-Feng Zhang, Hong Chen*. Impact of diethylhexyl phthalate on gene expression and development of mammary glands of pregnant mouse. Histochemistry and Cell Biology, 2015,144:389–402. (IF="3.054).

  Mingxun Li,Xiaomei Sun,Yang Zhou,Xuefeng Wei,Yujia Sun,Xianyong Lan,Chuzhao Lei,Hong Chen*. Nicotinamide and resveratrol regulate bovine adipogenesis through a SIRT1-dependent mechanism. Journal of Functional Foods, 2015,18:492–500.(IF="3.574)

  X. Sun, M. Li, Y. Sun, H. Cai, R. Li, X. Wei, X. Lan, Y. Huang, C. Lei, and H. Chen*. The evelopmental transcriptome landscape of bovine skeletal muscle defined by Ribo-Zero ribonucleic acid sequencing. Journal of Animal Science , 2015, 93:5648–5658.

  Hanfang Cai, Yang Zhou, WenchaoJia, BowenZhang, Xianyong Lan, Chuzhao Lei, Xintang Fang and Hong Chen*. Effects of SNPs and alternative splicing within HGF gene on its expression patterns in Qinchuan cattle. Journal of Animal Science and Biotechnology, 2015, 6:55-62. (IF="2.037)

  Yong‐Zhen Huang, Yu‐Jia SunMing‐Xun Li, Jing Wang, Jia‐Jie Sun, Chun‐Lei Zhang, Yu‐Tang Jia, Hong Chen*. Evaluation of the causality of the zinc finger BED-type containing 6 gene (ZBED6) for six important growth traits in Nanyang beef cattle. Animal Genetics, 2015,46(2):225-226. DOI:10.1111/age.12265(IFr="2.21)

  Yong-Zhen HuangYong-Jie JingYu-Jia SunXian-Yong LanChun-Lei ZhangEn-Liang SongHong Chen*. Exploring genotype–phenotype relationships of the LHX3 gene on growth traits in beef cattle. Gene2015,561(2):219–224(IF="2.138)

  Yujia Sun ,XianyongLan , Chuzhao Lei , Chunlei Zhang ,Hong Chen*. Haplotype combination of the bovine CFL2 gene sequence variants and association with growth traits in Qinchuan cattle. Gene ,2015,563(2): 136–141.

  J. Sun, T. S. Sonstegard, C. Li, Y. Huang1, Z. Li, X. Lan, C. Zhang, C. Lei, X. Zhao and H. Chen*. Altered microRNA expression in bovine skeletal muscle with age. Animal Genetics,2015,46(3):227–238.

  Y. H. Wang , C. L. Zhang , M. Plath, X. T. Fang , X. Y. Lan, Y. Zhou and H. Chen*. Global transcriptional profiling of longissimus thoracis muscle tissue in fetal and juvenile domestic goat using RNA sequencing. Animal Genetics, 2015,46:655–665.

  Zi-nian Wang, Han-fang Cai, Ming-xun Li, Xiu-kai Cao, Xian-yong Lan, Chu-zhao Lei, Hong Chen*. Tetra-primer ARMS-PCR identified four pivotal genetic variations in bovine PNPLA3 gene and its expression patterns。 Gene ,2016,575(2):.(IF="2.138)

  Zhang C, Wu H, Wang Y, Zhao Y, Fang X, Chen C, Chen H*. Expression Patterns of Circular RNAs from Primary Kinase Transcripts in the Mammary Glands of Lactating Rats. Journal of Breast Cancer ,2015 ,Sep;18(3):235-41.

  

  2014年

  Yong-Zhen Huang, Liang-Zhi Zhang, Xin-Sheng Lai, Ming-Xun Li, Yu-Jia Sun, Cong-Jun Li, Xian-Yong Lan, Chu-Zhao Lei, Chun-Lei Zhang, Xin Zhao & Hong Chen*. Transcription Factor ZBED6 Mediates IGF2 Gene Expression by Regulating Promoter Activity and DNA Methylation in Myoblasts. Scientific Reports,2014,4 : 4570.

  Yong-Zhen Huang,Jia-Jie Sun, Liang-Zhi Zhang, Cong-Jun Li, James E. Womack, Zhuan-Jian Li, Xian-Yong Lan, Chu-Zhao Lei, Chun-Lei Zhang, Xin Zhao & Hong Chen*. Genome-wide DNA Methylation Profiles and Their Relationships with mRNA and the microRNA Transcriptome in Bovine Muscle Tissue (Bos taurine). Scientific Reports,2014,4: 6546.

  Liangzhi Zhang,Shangang Jia,Mingjuan Yang,Yao Xu,Congjun Li,Jiajie Sun,Yongzhen Huang,Xianyong Lan,Chuzhao Lei,Yang Zhou,Chunlei Zhang,Xin Zhao,and Hong Chen*. Detection of copy number variations and their effects in Chinese bulls. BMC Genomics,2014,15:480.

  Liushuai Hua, Jing Wang, Mingxun Li, Xiaomei Sun, Liangzhi Zhang, Chuzhao Lei, Xianyong Lan, Xingtang Fang, Xin Zhao, Hong Chen*. An Asp7Gly Substitution in PPARG Is Associated with Decreased Transcriptional Activation Activity. PLoS ONE,2014,9(1): e86954.

  Jiajie Sun, Yang Zhou, Hanfang Cai, Xianyong Lan, Chuzhao Lei, Xin Zhao, Chunlei Zhang, Hong Chen*.  Discovery of Novel and Differentially Expressed MicroRNAs between Fetal and Adult Backfat in Cattle. PLoS ONE,2014,9(2):e90244.

  Jiajie Sun  Bowen Zhang, Xianyong Lan, Chunlei Zhang, Chuzhao Lei, Hong Chen*. Comparative Transcriptome Analysis Reveals Significant Differences in MicroRNA Expression and Their Target Genes between Adipose and Muscular Tissues in Cattle. PLoS ONE,2014,9(7):e102142.

  Yang Zhou, Jiajie Sun, Congjun Li, Yanhong Wang, Lan Li, Hanfang Cai, Xianyong Lan, Chuzhao Lei, Xin Zhao, Hong Chen*. Characterization of Transcriptional Complexity during Adipose Tissue Development in Bovines of Different Ages and Sexes. PLoS ONE ,2014 ,9(7):e101261.

  Yanhong Wang, Chunlei Zhang, Xingtang Fang, Yulong Zhao, Xiaohui Chen, Jiajie Sun, Yang Zhou, Jianjin Wang, Yongan Wang, Xianyong Lan, Hong Chen*. (2014) Identification and Profiling of microRNAs and Their Target Genes from Developing Caprine Skeletal Muscle. PLoS ONE,2014,9(5): e96857.

  Liangzhi Zhang, Mingjuan Yang, Congjun Li, Yao Xu, Jiajie Sun, Chuzhao Lei, Xianyong Lan, Chunlei Zhang, Hong Chen*. Identification and genetic effect of a variable duplication in the promoter region of the cattle ADIPOQ gene. Animal Genetics,2014,45(2):171-179.

  Y. Zhou, H. Cai, Y. Xu, J. Sun, X. Lan, C. Lei and H. Chen*. Novel isoforms of the bovine Nuclear factor I/X (CCAAT-binding transcription factor) transcript products and their diverse expression profiles. Animal Genetics, 2014,45, 581–584.

  Mingxun Li, Xiaomei Sun, Jing Jiang, Yujia Sun, Xianyong Lan, Chuzhao Lei, Chunlei Zhang and Hong Chen*. Tetra-primer ARMS–PCR is an efficient SNP genotyping method: with an example from SIRT2. Analytical methods, 2014, 6:1835.

  Yong-Zhen Huang,Zhao-Yang Zhan,Yu-JiaSun,Xiu-Kai Cao,Ming-XunLi,Jing Wang,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,HongChen*.Intragenic DNA methylation status down-regulates bovine IGF2 gene expression in different developmental stages. Gene,2014,534:356-361.

  Mei Liu, Mijie Li, Shaoqiang Wang, Yao Xu, Xianyong Lan, Zhuanjian Li, Chuzhao Lei, Dongying Yang, Yutang Jia,Hong Chen*. Association analysis of bovine Foxa2 gene single sequence variant and haplotype combinations with growth traits in Chinese cattle. Gene,2014, 536(2):385–392.

  Yao Xu,Tao Shi,Hanfang Cai,Yang Zhou,Xianyong Lan,Chunlei Zhang,Chuzhao Lei,Xinglei Qi,Hong Chen*. Associations of MYH3 gene copy number variations with transcriptional expression and growth traits in Chinese cattle. Gene,2014, 535(2):106–111.

  Zi-nian Wang, Mi-jie Li, Xian-yong Lan, Ming-xun Li, Chu-zhao Lei, Hong Chen*. Tetra-primer ARMS-PCR identifies the novel genetic variations of bovine HNF-4 alpha gene associating with growth traits. Gene,2014,546:206–213.(IF="2.082)

  Yonglong Dang, Mingxun Li, Mingjuan Yang, Xiukai Cao, Xianyong Lan, Chuzhao Lei, Chunlei Zhang, Qing Lin, Hong Chen*. Identification of bovine NPC1 gene cSNPs and their effects on body size traits of Qinchuan cattle. Gene,2014,540:153-160.

  Gang Ren, Yong-Zhen Huang, Tian-Bao Wei, Jun-Xia Liu, Xian-Yong Lan, Chu-ZhaoLei,Chun-Lei Zhang, Zhi-Ying Zhang, Xing-Lei Qi, Hong Chen*. Linkage disequilibrium and haplotype distribution of the bovine LHX4 gene in relation to growth. Gene,2014, 538:354–360.

  Zhuan-jian LiWen-jiao GuoYa-dong TianRui-li HanYu-jia SunJing XueXian-yong LanHong Chen* . Characterisation of the genetic effects of the ADFP gene and its association with production traits in dairy goats. Gene,2014, 538(2):244–250.

  2013年:

  Jiajie Sun, Mijie Li, Zhuanjian Li, Jing Xue, Xianyong Lan, Chunlei Zhang, Chuzhao Lei, Hong Chen*. Identification and profiling of conserved and novel microRNAs from Chinese Qinchuan bovine longissimus thoracis. BMC Genomics, 2013, 14: 42.

  Yong-Zhen Huang,Ming-Xun Li,Jing Wang,Zhao-Yang Zhan,Yu-Jia Sun,Jia-Jie Sun, Cong-Jun Li,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Hong Chen*. A 5′- Regulatory Region and Two Coding Region Polymorphisms Modulate Promoter Activity and Gene Expression of the Growth Suppressor Gene ZBED6 in Cattle. PLoS ONE, 2013, 8(11): e79744.

  Ming-xun Li, Xiao-mei Sun, Liang-zhi Zhang, Jing Wang, Yong-zhen Huang,Yu-jia Sun. Shen-rong Hu, Hong Chen*. A novel -274 C > G polymorphism in bovine SIRT1 gene contributes to diminished promoter activity and increased body size. Animal Genetics,2013, 44(5): 584-587.

  Yao Xu,Liangzhi Zhang,Tao Shi,Yang Zhou,Hanfang Cai,Xianyong Lan,Chunlei Zhang,Chuzhao Lei,Hong Chen*. Copy number variations of MICAL-L2shaping gene expression contribute to different phenotypes of cattle. Mamm Genome,2013,24:508–516.

  Hanfang Cai, Aimin Li, Xianyong Lan, Chuzhao Lei, Hong Chen*. Genetic variations of HGF gene and their effects on growth traits in Chinese cattle . Research in Veterinary Science, 2013, 95(2): 483-488.

  Wang AZhang YLi MLan XWang JChen H*. SNP identification in FBXO32 gene and their associations with growth traits in cattle. Gene,2013, 515(1): 181-186.

  Xiao-Mei Sun,Ming-Xun Li, Ai-Min Li, Xian-Yong Lan, Chu-Zhao Lei, Wei Ma, Liu-shuai Hua, Jing Wang, Shen-Rong Hu, Hong Chen*. Two novel intronic polymorphisms of bovine FGF21 gene are associated with body weight at 18 months in Chinese cattle. Livestock Science,2013,155:23–29. (IF="1.249)

  Yong-Zhen Huang, Ke-Yi Wang, Hua He,Qing-Wu Shen, Chu-Zhao Lei, Xian-Yong Lan, Chun-Lei Zhang, and Hong Chen*. Haplotype distribution in the GLI3 gene and their associations with growth traits in cattle. Gene, 2013, 513(1):141–146.

  Yong-Zhen Huang,Jing Wang,Zhao-Yang Zhan,Xiu-Kai Cao,Yu-JiaSun,Xian-Yong Lan,Chu-ZhaoLei,Chun-Lei Zhang,Hong Chen*. Assessment of association between variants and haplotypes of the IGF2 gene in beef cattle. Gene ,2013 ,528:139-145.

  Yong-Zhen Huang,Hua He,Zhao-Yang Zhan,Yu-Jia Sun,Ming-Xun Li,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Hong Chen*. Relationship of polymorphisms within ZBED6 gene and growth traits in beef cattle. Gene,2013,526:107–111.

  Jing Xue, Yujia Sun, Wenjiao Guo, Ziqi Yang, Huibin Tian, Chunlei Zhang, Chuzhao Lei, Xianyong Lan, Hong Chen*. Haplotypes and effects on growth traits of bovineWnt7agene in Chinese Qinchuan cattle. Gene,2013,524(2):241-245.

  Mingxun Li, Xiaomei Sun, Liushuai Hua, Xinsheng Lai, Xianyong Lan, Chuzhao Lei, Chunlei Zhang, Xinglei Qi,Hong Chen*. SIRT1 gene polymorphisms are associated with growth traits in Nanyang cattle. Molecular and Cellular Probes, 2013, 27(7-8): 215-220.

  Mingxun Li, Xiaomei Sun, Liushuai Hua, Yongzhen Huang, Jing Wang, Xiukai Cao, Zhaoyang Zhan, Xianyong Lan, Chunlei Zhang,Shanzhai Liu, Hong Chen*. Molecular characterization, alternative splicing and expression analysis of bovine DBC1. Gene,2013,527(2): 689-693.

  Mingjuan Yang,Junhui Fu,Xianyong Lan,Yujia Sun,Chuzhao Lei,Chunlei Zhang,Hong Chen*. Effect of genetic variations within the SH2B2 gene on the growth of Chinese cattle. Gene,2013,528:314–319.

  Yong-Zhen Huang,Xin-Lei Wang,Hua He,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Hong Chen*. Identification and genetic effect of haplotype in the bovine BMP7gene. Gene,2013,532:281–287.

  Zhou, Yang, Li C, Cai Hanfang, Xu Yao, Lan Xianyong, Lei Chuzhao & Chen Hong*. Novel polymorphisms of the APOA2 gene and its promoter region affect body traits in cattle. Gene, 2013,531(2): 288-293.

  Xiu-Kai Cao,JingWang,Xian-Yong Lan,Chu-Zhao Lei,Chun-Lei Zhang,Xing-Lei Qi,Hong Chen*. Genetic variants in BMP8B gene are associated with growth traits in Chinese native cattle. Gene,2013,532:108–113.

  Sun Y., Xue J., Guo W., Li M., Huang Y., Lan X., Lei C., Zhang C. and Chen H*. Haplotypes of bovine FoxO1 gene sequence variants and association with growth traits in Qinchuan cattle. Journal of Genetics ,2013 ,92, e8–e14.

  Gao Y, Liu D, Ma W, Li A, Lan X, Zhang C, Lei C and Chen H*. Two novel SNPs in the coding region of bovine VDR gene and their associations with growth traits. Journal of Genetics,2013,92, e53–e59.

  

  2012年:

  Zhuanjian Li, Xianyong Lan, Wenjiao Guo, Jiajie Sun, Yongzhen Huang, Jing Wang, Tinghua Huang, Chuozhao Lei, Xingtang Fang, Hong Chen*. Comparative Transcriptome Profiling of Dairy Goat MicroRNAs from Dry Period and Peak Lactation Mammary Gland Tissues. PLoS ONE, 2012, 7(12): e52388.

  Mingjuan Yang, Lian Qu, Junxia Liu, Xianyong Lan, Liangzhi Zhang, Jing Wang, Chuzhao Lei, Hong Chen*. Polymorphisms and effects on growth traits of the SH2B1 gene in Chinese cattle. Livestock Science,2012,143:283–288.

  Liushuai Hua, Mingxun Li, Xiaomei Sun, Jing Wang, Zhuanjian Li, Yao Xu, Shenrong Hu and Hong Chen*. A dual color fluorescent reporter system for the real time detection of promoter activityBiotechnology Letters ,2012 ,34 (5):823-830.

  Bao Zhang, Gaofeng Zhao, Xianyong Lan, Chuzhao Lei, Chunlei Zhang,Hong Chen*. Polymorphism in GHRH gene and its association with growth traits in Chinese native cattle. Research in Verterinary Science. 2012,92(2): 243-246.

  B. Zhang,F. Peñagaricano,H. Chen and H. Khatib. Novel transcripts and alternatively spliced genes are associated with early development in bovine embryos. Animal ,2012 ,1-7.

  Z.J. Li,X.Y. Lan,J.J. Sun,J. Wang,Y.Z. Huang,W.J. Guo,B. Zhang,C.Z. Lei,C.L. Zhang,H. Chen*. Molecular characterization and haplotype combination of PrRP gene polymorphism and its association with production traits in Chinese native goats. Small Ruminant Research,2012,105(1–3):69-78.

  Bao Zhang,Yi Kun Guo,Shengbin Li,Liang Zhi Zhang,Xian Yong Lan,Shen Rong Hu,Hong Chen*. Genotype and haplotype analysis of the AZGP1 gene in cattle. Molecular Biology Reports, 2012,39: 10475–10479.

  

  2011年:

  Li Zhang, Ai-Ling Zhang, Liang-Zhi Zhang, Qin Zhang, Chun-Lei Zhang, Xian-Yong Lan, Hong Chen*. Association analysis between variants in bovine NPY gene and growth traits in Nanyang cattle (Bos taurus). General and Comparative Endocrinology, 2011, 170: 189–192.

  Y. Z. Huang, H. He, J. Wang, Z. J. Li, X. Y. Lan, C. Z. Lei, E. P. Zhang, C. L. Zhang,J. Q. Wang,Q. W. Shen and H. Chen*. Sequence variants in the bovine nucleophosmin 1 gene, their linkage and their associations with body weight in native cattle breeds in China. Animal Genetics, 2011, 42, 556–559 .

  Bao Zhang, Ya Zhang, Liangzhi Zhang, Jing Wang, Zhuanjian Li and Hong Chen*. Allelic Polymorphism Detected in the Bovine FTO Gene. Molecular Biotechnology, 2011, 49(3): 257-262.

  Zhang Q, Zhao S, Chen H*, Zhang L, Zhang L, Li F, Wang X. SNP discovery and haplotype analysis in the bovine PRKAA2 gene. Molecular Biology Reports, 2011, 38(3):1551-1556.

  C.L. Zhang,Y.H. Wang,H. Chen*,C.Z. Lei,X.T. Fang. The polymorphisms of bovine melanocortin-3 receptor pseudogene. Research in Veterinary Science, 2011, 90: 241-244.

  Shan Wang,Xin Cai,Kai Xue,Hong Chen*. Polymorphisms of MRF4 and H-FABP genes association with growth traits in Qinchuan cattle and related hybrids. Molecular Biology Reports, 2011, 38: 1013–1020.

  C. Z. Lei, C. M. Zhang, S. Weining, M. G. Campana, M. A. Bower, X. M. Zhang, L. Liu,X. Y. Lan and H. Chen*. Genetic diversity of mitochondrial cytochrome b gene in Chinese native buffalo. Animal Genetics, 2011,42, 432–436.

  2010年:

  Ai-ling Zhang,Li Zhang,Liang-zhi Zhang,Hong Chen*,Xian-yong Lan,Chun-lei Zhang,Cun-fang Zhang. An efficient and rapid method for gene cloning from eukaryotic genomic DNA using overlap-PCR: With an example of cattle Ghrelin gene. Biochemical and Biophysical Research Communications, 2010, 391: 1490-1493.

  Shan Wang, Chunyan Tian, Tingtiang Xiao, Guichun Xing, Fuchu He, Lingqiang Zhang, Hong Chen*. Differential regulation of Apak by various DNA damage signals. Mol Cell Biochem, 2010, 333:181-187.

  X. Cai, H. Chen*, C. Lei. Matrilineal genetic inter-introgression of Bos taurus and Bos indicus in China. Livestock Science, 2010, 128: 12–19.

  Chuanying Pan,Baisong Lu,Hong Chen*,Colin E. Bishop*. Reprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC. Mol Biol Rep, 2010, 37: 2117–2124.

  Han, R.L., Lan, X.Y., Zhang, L.Z., Ren, G., Jing, Y.J., Li, M.J., Zhang, B., Zhao, M., Guo, Y.K., Kang, X.T., Chen, H*. A novel single-nucleotide polymorphism of the visfatin gene and its associations with performance traits in the chicken. J Appl Genet, 2010,51, 59-65.

  Shangang Jia,Yan Zhou,Chuzhao Lei,Xiuqing Zhang,Ru Yao,Zhiying Zhang,Xingtang Fang,Hong Chen*. A new insight into cattle's maternal origin in six Asian countries. Journal of Genetics and Genomics, 2010, 37: 173-180.

  Chuanying Pan, Amy Hicks, Hong Chen*, Colin E. Bishop*. SNL fibroblast feeder layers support derivation and maintenance of human induced pluripotent stem cells. Journal of Genetics and Genomics,2010, 37: 241−248.

  Pan C, Lan X, Chen H*, Bishop CE. An economical single-sided antibody incubation method for Western blotting. J Virol Methods,2010,169(2): 409-11.

  2009年:

  C. Z. Lei, R. Su, M. A. Bower, C. J. Edwards, X. B. Wang, S. Weining,L. Liu, W. M. Xie, F. Li, R. Y. Liu, Y. S. Zhang, C. M. Zhang and H. Chen*. Multiple maternal origins of native modern and ancient horse populations in China. Animal Genetics, 2009,40, 933–944.

  ChunLei Zhang, YanHong Wang, Hong Chen*, ChuanWen Gu, XingTang Fang. SLC11A1 gene polymorphisms are not associated to somatic cell score and milk yield in Chinese Holstein. Veterinary Immunology and Immunopathology,2009,127:389–392.

  Bifang Hao,Jinshan Huang,Xiulian Sun,Fei Deng,Yanfang Zhang,Hualin Wang, Hong Chen* and Zhihong Hu*. Variants of open reading frame Bm126 in wild-type Bombyx mori nucleopolyhedrovirus isolates exhibit functional differences. Journal of General Virology , 2009, 90: 153-161.

  X.Y. Lan, C.Y. Pan, J.Y. Li, Y.W. Guo, S. Hu, J. Wang, Y.B. Liu, S.R. Hu, C.Z. Lei, H. Chen*. Twelve novel SNPs of the goat POU1F1 gene and their associations with cashmere traits. Small Ruminant Research,2009, 85:116-121.

  Qin Zhang,Hong Chen*,Sheng Zhao,Li Zhang,Liangzhi Zhang,Fei Li,Xueming Wang. Single Nucleotide Polymorphisms and Haplotypic Diversity in the Bovine PRKAB1 Gene. Mol Biotechnol ,2009 ,43:193–199.

  

  2008年以前:

  C. Z. Lei, W. Zhang , H. Chen*, F. Lu, R. Y. Liu , X. Y. Yang, H. C. Zhang , Z. G. Liu, L. B. Yao, Z. F. Lu and Z. L. Zhao. Independent maternal origin of Chinese swamp buffalo (Bubalus bubalis), Animal Genetics ,2007,38(2): 97-102.

  M. Zhao, X. Wang, H. Chen*, X.Y. Lan, Y.K. Guo, J.Y. Li, T.B. Wei, Y.J. Jing, S.Q. Liu, M.H. Zhang, Q.W. Gao. The PCR-SSCP and DNA sequencing methods detecting a large deletion mutation at KAP6.2 locus in the cashmere goat. Small Ruminant Research,2008,75:243–246.

  C.L. Zhang, H. Chen*, Y.H. Wang, R. F. Zhang, X.Y. Lan, C.Z. Lei, L. Zhang, A.L. Zhang, and S.R. Hu. Association of a Missence Mutation in Serotonin Receptor 1B (HTR1B) Gene with Milk Production Traits. Research in Veterinary Science ,2008 ,85:265-268.

  Chunlei Zhang, Hong Chen*, Yanhong Wang, Xianyong Lan, Chuzhao Lei, Xingtang Fang. The polymorphisms of bovine CART gene and their associations with cattle growth traits. Journal of Biosciences ,2008 ,33:365–370.

  M.J. Li, X.Y. Lan, H. Chen*, L.Z. Zhang, Y.J. Jing, G. Ren, T.B. Wei, X. Wang. The novel missense mutation of goat LHX4 gene, Small Ruminant Research,2008,79:109–112.

  Weibin SUN,Hong CHEN*,Chuzhao LEI,Xueqin LEI,Yinghan ZHANG. Genetic variation in eight Chinese cattle breeds based on the analysis of microsatellite markers。 Genetics Selection Evolution ,2008,40:681–692。

  H. Yu,X. Wang,H. Chen*,M. Wang,M. Zhao,X.Y. Lan,C.Z. Lei, K.Y.Wang,X.S. Lai,X.L.Wang. The polymorphism of a novel 30 bp-deletion mutation at KAP9.2 locus in the cashmere goat. Small Ruminant Research ,2008 ,80:111–115.

  CHEN Hong*, CAI Xin, LEIChu-zhao, FANG Xing-tang, ZHU Bi-cai,ZHANG Bao. Bos tauraus and Bos indicus: the Main Ancestress of Cattle Breeds in China Revealed by mtDNA Diversity(Abstract). Cell Research, 2006,16: S109.

  Xin Cai,Hong Chen*,Chuzhao Lei,Shan Wang,Kai Xue,Bao Zhang. mtDNA diversity and genetic lineages of eighteen cattle breeds from Bos taurus and Bos indicus in China. Genetica, 2007,131: 175–183.

  ChunLei Zhang, Yanhong Wang, Hong Chen*, Xianyong Lan and Chuzhao Lei,. Enhance the Efficiency of Single-Strand Conformation Polymorphism Analysis by short Polyacrylamide Gel and Quick Low-Background Silver Staining. Analytical Biochemistry, 2007, 365:286–287.

  X. Wang, Y.H. Ma, H. Chen* and W.J. Guan. Genetic and phylogenetic studies of Chinese native sheep breeds (Ovis aries) based on mtDNA D-loop sequences. Small Ruminant Research, 2007, 72:232-236.

  X. Y. Lan, C. Y. Pan, H. Chen*, and C. Z. Lei. A DdeI PCR-RFLP detecting genetic variation of goat POU1F1 gene. Canadian Journal of Animal Science, 2007, 87(1):13-14.

  X.Y. Lan, C.Y. Pan, H. Chen*, C.L. Zhang, J.Y. Li, M. Zhao, C.Z. Lei, A.L. Zhang, L. Zhang. An AluI PCR-RFLP detecting a silent allele at the goat POU1F1 locus and its association with production traits. Small Ruminant Research ,2007 ,73:8–12.

  X.Y. Lan, C.Y. Pan , H. Chen*, C.Z. Lei, S.Q. Liu,Y.B. Zhang, L.J. Min, J. Yu, J.Y. Li, M. Zhao, S.R. Hu. The HaeIII and XspI PCR-RFLPs detecting polymorphisms at the goat IGFBP-3 locus. Small Ruminant Research ,2007 ,73:283–286.

  Ai-Ling Zhang, Hui Liu, Ming-Ming Yang, Yue-Sheng Gong, Hong Chen. Assay and characterization of a strong promoter element from B. subtilis. Biochemical and Biophysical Research Communications. 2007,354(1): 90-95.

  Shangang Jia, Hong Chen*, Guixiang Zhang, Zhigang Wang, Chuzhao Lei, Ru Yao, Xu Han. Genetic Variation of Mitochondrial D-loop Region and Evolution Analysis in Some Chinese Cattle Breeds. Journal of Genetics and Genomics , 2007,34(6): 510-518.

  YANG Dong-ying,CHEN Hong*,ZHANG ZHeng-feng,LAN Xian-yong,ZHANG Liang-zhi,HU Shen-rong,SU Li-hong,WANG Xin-zhuang,WANG Ju-qiang. Single Nucleotide Conformation Polymorphisms of Leptin Gene in Chinese Cattle. Journal of Genetics and Genomics,2007 34(5):400-405.

  Weibin Sun,Hong Chen*,Chuzhao Lei, Xueqin Lei,Yinghan Zhang. Study on Population Genetic Characteristics of Qinchuan Cows Using Microsatellite Markers. Journal of genetics and Genomics, 2007, 34(1):17-25.

  Xin Cai, Hong Chen*, Shan Wang, Kai Xue, Chuzhao Lei. Polymorphisms of a Y Chromosome Specific Microsatellite in Chinese Cattle Breeds. Genetics Selection Evolution,2006,38:525-534 .

  C. Z. Lei, H. Chen*, H. C. Zhang, X. Cai, R. Y. Liu, L. Y. Luo, C. F. Wang, W. Zhang, Q. L. Ge, R. F. Zhang, X. Y. Lan and W. B. Sun. Origin and phylogeographical structure of Chinese cattle. Animal Genetics, 2006, 37: 579–582.

  XUE Kai, CHEN Hong*, WANG Shan,CAI Xin, LIU Bo, ZHANG Cun-fang1 LEI Chu-zhao, WANG Xin-zhuang, WANG Yi-min, NIU Hui. Effect of Genetic Variations of POU1F1 Gene on Growth Traits of Nanyang Cattle.  Acta Genetica Sinica, 2006,  33 (10):901–907.

  WANG Xin, MA Yue-hui, CHEN Hong*. Analysis of the genetic Diversity and Phylogenetic Evolution of Chinese Sheep Based on Cyt b Gene Sequences. Acta Genetica Sinica, 2006,  33 (12):1081–1086.

  

  Adress:

  Northwest A&F University

  College of Animal Sciences and Technology

  Department of Animal Sciences

  

  Xinong Road No.22

  Yangling, Shaanxi, 712100,P. R. China

  Telephone: ++86-29-87092102

  Fax:      ++86-29-87092164

  E-mail:  chenhong1212@263.netchenhong1212@126.com