Zaizhao Wang

　　 　　

Zaizhao Wang

Address:

22 Xinong Road, Yangling, Shaanxi 712100 China

College of Animal Science and Technology, Northwest A&F University

Email:

zzwang@nwsuaf.edu.cn

Basic information

I received PhD degree of marine biology in Institute of Oceanology, Chinese Academy of Sciences in Nov, 2000.I completed postdoctoral training in Medical college of Georgia, Augusta GA, USA from 2004 to 2007. I joined the faculty as a professor in 2008 in the Department of Aquaculture of College of Animal Science and Technology, Northwest A&F University.

Research area

Protection of fish resources and fish ecological restoration. Aquatic pollution ecology. The selection and dissemination of antibiotic resistant bacteria and antibiotic resistant genes in aquatic ecosystem. Algae-bacteria interaction and its application in contamination remediation.

Project hosted

1. Chemical ecological study on dissemination of antibiotic resistance in aquatic ecosystem based on algae-bacteria interaction. Funded by National Natural Science Foundation of China, No. 32171626, 2022.01-2025.12.

2.The selection and dissemination mechanism of antibiotic resistancefor bacteria under environmental pressure in urban river. Funded by National Natural Science Foundation of China,No.31870487, 2019.01-2022.12.

3. The detrimental effects of BPA on spermatogenesis in fish and their molecular mechanisms. Funded by National Natural Science Foundation of China, No.31670523, 2017.01-2020, 12.

4. DNA methylation involving in BPA's disturbance to steroid hormone biosynthesis and actions and its mechanisms. Funded by National Natural Science Foundation of China, No.31470553, 2015.01-2018.12.

5. An ecotoxicogenomics study on ovarian development in rare minnow exposure to bisphenol A. Funded by National Natural Science Foundation of China, No.31270547, 2013.01-2016.12.

Publication

[1] Xue, X., Li, X., Liu, J., Zhu, L., Zhou, L., Jia, J., Wang, Z., 2023. Field-realistic dose of cefotaxime enhances potential mobility of β-lactam resistance genes in the gut microbiota of zebrafish (Danio rerio).Environ. Pollut. 257, 106459.

[2] Li, X., Xue, X., Jia, J., Zou, X., Guan, Y., Zhu, L., Wang, Z., 2023. Nonsteroidal anti-inflammatory drug diclofenac accelerates the emergence of antibiotic resistance via mutagenesis. Environ. Pollut. 326, 121457.

[3] Fan, X., Zhang, D., Hou, T., Zhang, Q.,Wang, Z., 2023. Insight into the health risk implicated in mitochondrial toxicity of dibutyl phthalate exposure on zebrafish (Danio rerio) cells. Chemosphere 326, 138510.

[4] Zhou, L., Liu, K., Zhao, Y., Cui, L., Dong, C., Wang, Z., 2022.Increasing salinization of freshwater limits invasiveness of a live-bearing fish: Insights from behavioral and life-history traits. Environ. Pollut.308, 119658.

[5] Guan, Y., Jia, J., Fan, X., Li, K., Wang, Z., 2022. Anthropogenic impacts on antibiotic resistance genes and their hosts from pristine to urban river using metagenomic and binning approaches. Aquat. Toxicol. 249,106221.

[6] Zhu, L., Guan, Y., Li, X., Xiong, X., Liu, J., Wang, Z., 2022. BPA disrupts the SC barrier integrity by activating the cytokines/JNK signaling pathway in rare minnow Gobiocyprisrarus. Aquat. Toxicol. 245,106124.

[7] Xue, X., Wang, L., Xing, H., Zhao, Y., Li, X., Wang, G., Wang, Z., 2021.Characteristics of phytoplankton-zooplankton communities and the roles in the transmission of antibiotic resistance genes under the pressure of river contamination. Sci. Total Environ. 780, 146452.

[8] Zhu, L., Wang, L., Fan, X., Dong, C., Wang, G., Wang, Z., 2021.Chronic exposure to Bisphenol A resulted in alterations of reproductive functions via immune defense, oxidative damage and disruption DNA/histone methylation in male rare minnow Gobiocyprisrarus.Aquat. Toxicol. 236,105849.

[9] Zhu, L., Liu, Y., Xue, X., Yuan, C., Wang, Z., 2021.BPA's transgenerational disturbance to transcription of ovarian steroidogenic genes in rare minnow Gobiocyprisrarus via DNA and histone methylation. Sci. Total Environ. 762, 143055.

[10] Xue, X., Jia, J., Yue, X., Guan, Y., Zhu, L., Wang, Z., 2021. River contamination shapes the microbiome and antibiotic resistance in sharpbelly (Hemiculterleucisculus). Environ. Pollut.268 (A), 115796.

[11] Fan, X., Hou, T., Guan, Y., Li, X., Zhang, S., Wang, Z., 2020.Genomic responses of DNA methylation and transcript profiles in zebrafish cells upon nutrient deprivation stress.Sci. Total Environ. 722, 137980.

[12] Guan, Y., Zhang, T., He, J., Jia, J., Zhu, L., Wang, Z., 2019. Bisphenol A disturbed the lipid metabolism mediated by sterol regulatory element binding protein 1 in rare minnow Gobiocyprisrarus.Aquat. Toxicol. 207, 179-186.

[13] Wang, S., Zhu, Z., He, J., Yue, X., Pan, J., Wang, Z., 2018. Steroidal and phenolic endocrine disrupting chemicals (EDCs) in surface water of Bahe River, China: Distribution, bioaccumulation, risk assessment and estrogenic effect on Hemiculterleucisculus. Environ. Pollut. 243,103-114.

[14] Jia J., Guan Y., Cheng, M., Chen, H., He, J., Wang, S., Wang, Z., 2018. Occurrence and distribution of antibiotics and antibiotic resistance genes in Ba River, China. Sci. Total Environ. 642, 1136-1144.

[15] Zhang, Y., Guan, Y., Zhang, T., Yuan, C., Liu, Y., Wang, Z., 2018. Adult exposure to bisphenol A in rare minnow Gobiocyprisrarus reduces sperm quality with disruption of testicular aquaporins.Chemosphere 193, 365-375.