Xiaopeng An

　　 　　

Basic Information

An Xiaopeng, Ph.D. (postdoctoral), Researcher, Ph.D. Supervisor. From 2003 to 2007, pursued undergraduate studies at Northwest A&F University. Followed by master's studies at the same university from 2007 to 2010. Completed doctoral studies from 2010 to 2013 at Northwest A&F University, and have been teaching at the university since. Presently hold the position of Chief Expert at the Heshui Dairy Sheep Experimental Demonstration Base of Northwest A&F University and serve as a Young Breeding Expert in the Yangling Demonstration Zone.

Work Experience

July 2013-December 2015,Lecturer, College of Animal Science and Technology, Northwest A&F University

January 2016-December 2022, Associate Professor, College of Animal Science and Technology, Northwest A&F University

January 2023-Present, Researcher, College of Animal Science and Technology, Northwest A&F University

Honors and Awards

1.Doctoral dissertation titled "Selection of Candidate Genes for Goat Reproductive Traits and Study of Their Multi-Gene Aggregation Effects" was awarded the Outstanding Ph.D. Dissertation of Shaanxi Province.

2. In 2019, was involved in the research and application of "Key Technologies for High-Quality Development of Dairy Goat Industry", which received the First Prize for Scientific and Technological Progress in Shaanxi Province (Fourth Place); the research on "Key Technologies for High-Quality and Efficient Dairy Goat Industry" earned the First Prize for Collaborative Innovation Achievements of Industry, Education, and Research in China (Second Place); in 2021, the integration and promotion of "Integrated Innovation and Promotion of Technical Standards for the Dairy Goat Industry Chain" achieved the First Prize for Agricultural Technology Promotion Results in Shaanxi Province (Second Place); in 2022, the construction and application of the "Integrated Development Model of the Dairy Goat Industry Chain" received the National Agriculture, Forestry, and Fisheries Harvest Award - Agricultural Technology Promotion and Cooperation Award (Second Place).

3.Guided undergraduate students in their participation in the "Ecological Livestock Farm Planning and Design" project, which won the First Prize in individual performance and the Grand Prize in team performance at the 3rd National Animal Science Skills Competition. I was also honored with the Outstanding Guidance Teacher Award at the 3rd National Animal Science Skills Competition.

4. Participation in the "Three Visits to the Countryside" scientific and technological assistance to agriculture activity organized by the Communist Youth League Central Committee, resulted in my recognition as an Advanced Individual in the "Three Visits to the Countryside" Social Practice Activity.

5. The micro-course "Nutrition and Functions of Goat Milk" received the Second Prize in the National University Agriculture and Forestry Professional Micro-Course Teaching Competition.

6.Guided undergraduate students in the research project "Molecular Mechanism of CircRNA8220/miR-8516 Regulating Lactation and Apoptosis in Dairy Goat Mammary Epithelial Cells", which won the First Prize in the CULSC National College Student Life Science Competition.

Scientific Research

1. 1.Research orientation

Animal Biotechnology and Regulation of Animal Reproductive Physiology.

2. Selected Projects Led

(1) Heshui Dairy Sheep Experimental Demonstration Base at Northwest A&F University, 2022-2024, 2.1 million RMB.

(2) Introduction of High-Quality Genetic Resources and Breeding of New Varieties of Dairy Goats, Shaanxi Provincial Key Industry Innovation Chain (Cluster), 2020-2023, 800,000 RMB.

(3) Breeding and Demonstration of Core Population of High-Quality and High-Yield Black and White Dairy Goats, Shaanxi Provincial Department of Agriculture, 2020-2021, 200,000 RMB.

(4) Study on the Regulation Mechanism of Novel-miR-3880 in Goat Milk Protein Expression, National Natural Science Foundation of China, 2017-2019, 200,000 RMB.

(5) Breeding and Hybrid Utilization of Alpine Dairy Goats, Shaanxi Provincial Department of Agriculture, 2019-2020, 200,000 RMB.

(6) Study on the Regulation Mechanism of Novel-miR-8516 in Goat Milk Protein Expression, China Postdoctoral Science Foundation Special Funding, 2016-2017, 150,000 RMB.

(7) Study on the Regulation Mechanism of KITLG Gene 3′UTR Mutation on Reproductive Traits in Dairy Goats, China Postdoctoral Science Foundation General Funding, 2014-2016, 50,000 RMB.

1. 3.Representative Publications

(1) Wang ZH, He YL, Liu SJ, Xu XL, Song YX, Zhang L, An XP*. (2023) Toxic effects of zinc oxide nanoparticles as a food additive in goat mammary epithelial cells. Food Research International 167: 112682 (IF="8.1).

(2) An XP, Ma HD, Liu YH, Li F, Song YX, Li G, Bai YY, Cao BY*. (2020) Effects of miR-101-3p on goat granulosa cells in vitro and ovarian development in vivo via STC1. Journal of animal science and biotechnology 11(1): 1-20 (IF="7).

(3) An XP, Ma HD, Han P, Zhu C, Cao BY*. (2018) Genome-wide differences in DNA methylation changes in caprine ovaries between oestrous and dioestrous phases. Journal of animal science and biotechnology 9: 85 (IF="7).

(4) Liu YH, Hou JX, Zhang M, Seleh‐Zo E, Wang JG, Cao BY, An XP*. (2020) circ‐016910 sponges miR‐574‐5p to regulate cell physiology and milk synthesis via MAPK and PI3K/AKT–mTOR pathways in GMECs. Journal of cellular physiology 235(5): 4198-4216 (IF="5.6).

(5) An XP, Zhang Y, Li F, Wang ZH, Yang SH, Cao BY. (2021) Whole transcriptome analysis: implication to estrous cycle regulation. Biology 10(6): 464 (IF="4.2).

(6) Zhu C, Jiang Y, Zhu JR, He YL, Yin H, Duan QY, Zhang L, Cao BY, An XP*. (2020) CircRNA8220 sponges MiR-8516 to regulate cell viability and milk synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR pathways in goat mammary epithelial cells. Animals 10(8): 1347 (IF="3).

(7) Zhu C, Zhu JR, Duan QY, Jiang Y, Yin H, He YL, Li F, An XP*. (2021) Exploration of the lactation function of protein phosphorylation sites in goat mammary tissues by phosphoproteome analysis. BMC genomics 22: 1-11 (IF="4.4).

(8) Wang PJ, Liu SJ, Zhu C, Duan QY, Jiang Y, Gao KX, Bu QQ, Cao BY, An XP*. (2020) MiR-29 regulates the function of goat granulosa cell by targeting PTX3 via the PI3K/AKT/mTOR and Erk1/2 signaling pathways. Journal of steroid biochemistry and molecular biology 202: 105722 (IF="4.1).

4.Granted Invention Patents

（1）An Xiaopeng, Jiang Yue, Duan Quyu, Zhu Junru, Yin Hao, Hou Jinxing, Song Yuxuan,Li Guang, Zhang Lei,Cao Binyun.Use of Target Gene SLC4A8 in Preparing Drug for Regulating Secretion of B-Casein from Mamary Epithelial Cell（International patent）.Patent number：2028308.

(2) An Xiaopeng, Li Fu, Hou Jinxing, Cao Binyun, Song Yuxuan, Zhang Lei, Li Guang, Fu Mingzhe, Shu Guowei. Primer Set, Detection Method, and Breeding Method for High-Quality and High-Yield Dairy Goats. Patent Number: ZL201810193253.3.

(3) An Xiaopeng, Hou Jinxing, Song Yuxuan, Ma Haidong, Li Guang, Cao Binyun. Molecular Marker Method for Selecting Goat Growth Traits Using Nucleolar Phosphoprotein Gene. Patent Number: ZL201710501338.9.

(4) Cao Binyun, An Xiaopeng, Hou Jinxing, Wang Lixin, Wang Jiangang, Song Yuxuan. Method for Detecting Five Base Mutations Polymorphism in Goat Growth Hormone Gene Coding Region. Patent Number: ZL201010199157.3.

(5) Cao Binyun, An Xiaopeng, Hou Jinxing, Wang Jiangang, Song Yuxuan, Yang Mingming, Zhu Guangqin, Wang Yunfei, Cui Yihong, Chen Qiuju. Molecular Marker Selection Method for Goat Reproductive Traits. Patent Number: ZL201010263060.4.

(6) Cao Binyun, An Xiaopeng, Yan Quanmei, Hou Jinxing, Wang Jiangang, Song Yuxuan, Yang Mingming, Zhu Guangqin, Wang Yunfei, Cui Yihong, Chen Qiuju. Method for Detecting Base Mutation Polymorphism in Goat Gonadotropin-Releasing Hormone and Growth Differentiation Factor 9 Genes. Patent Number: ZL201010199506.1.

(7) Cao Binyun, Hou Jinxing, An Xiaopeng, Wang Jiangang, Song Yuxuan. Method for Breeding Dairy Goats with Milk Production Traits Using Dual-Gene Aggregation Effect. Patent Number: ZL201310449829.5.5.

5. Developed Shaanxi Provincial Local Standards

(1) An Xiaopeng, Hou Jinxing, Cao Fangjun, et al. Dairy Goat Farming Technical Specifications Part 3: Dual-Gene Breeding of Elite Varieties, DB61/T 1521.3-2021

(2) An Xiaopeng, Cao Fangjun, Ge Wupeng, et al. Dairy Goat Farming Technical Specifications Part 11: Machine Milking, DB61/T 1521.11-2021

6. Engagements in Society

(1) Serving as a Shaanxi Province Special Commissioner for Science and Technology, Shaanxi Province "Three Zones" Scientific and Technological Talent, Expert and Secretary-General of the Shaanxi Provincial Dairy Sheep Industry Technical System (Agricultural Department), Member of the Dairy Goat Expert Committee of the Shaanxi Dairy Industry Association, and Member of the Chinese Specialized Committee on Sheep and Goat Milk.

(2)Acting as a reviewer for 10 international journals including "Animal Genetics," "Animal Reproduction Science," "Journal of Cellular Physiology," "Domestic Animal Endocrinology," and "Small Ruminant Research."ect.