Linsen Zan

　　 　　

Ⅰ. Personal information

Zan Linsen, Ph.D, Professor, doctoral supervisor,NPC deputy,enjoying special government allowances of State Council. Prof. Zan has been engaged in teaching, scientific research, and technology promotion of genetic improvement of beef and dairy cattle, biotechnology breeding, healthy aquaculture, as well as industrialization engineering. Currently, he serves as the head of the Beef Cattle Research Center of Northwest A&F University and the National Beef Cattle Improvement Center, deputy head of the National Beef Cattle Genetic Improvement Program Expert Group, committee member of the Cattle Breed Validation Committee of the National Livestock and Poultry Genetic Resources Committee, scientist of the National Beef Cattle and Yak Industrial Technology System, and the vice president of the Cattle Branch of the China Animal Husbandry Association. Moreover, he takes charge as the vice chairman of the China Improved Yellow Cattle Breeding Committee, executive director of the Dairy Association, and the head of the Shaanxi Beef Industry Engineering Technology Research Center.

Since his working years, Prof. Zan has presided over or mainly participated in more than forty science and technology plan projects, including at the national, provincial, or ministry level. Among all the completions, two won the first & second prizes of the National Science and Technology Progress Award, and twenty-one won the provincial awards. Including the provincial teaching achievement grand prize (one) and the provincial science & technology achievement prizes (ten First, nine Second, and five Third). As of today, he has published over four hundred academic papers (over 230 of which are included in SCI and EI) and twenty textbooks, obtained over thirty patents, and compiled over fifty national & industrial standards. Furthermore, he was honored as “National Outstanding Scientific and Technological Worker,” “National Outstanding Talents of Agricultural Scientific Research,” “National Model of Agricultural Science and Technology Promotion,” “Advanced Workers of China’s Animal Husbandry Industry,” “National Advanced Workers of Cattle Breeding and Improvement,” “Top Ten Outstanding Young People of Shaanxi Province,” “Shaanxi Provincial Three-Five Talents,” “Outstanding Expert of Yangling Demonstration Area,” “Top Talent of Northwest A&F University.” He has received funding from the 7th Youth Science and Technology Award of the Chinese Society of Agriculture and the 5th Huo Yingdong Education Fund. Moreover, he has received the CCTV Agriculture Award,the Baosteel Outstanding Teacher Award, the Contribution Award to Revitalizing China’s Animal Husbandry, the Special Award for China’s Invention and Entrepreneurship, and the Outstanding Contribution Award for China's Industry-academy-research Cooperation.

Currently, his part-time social appointments include being Deputy to the 13th National People's Congress, Member of the Standing Committee and the Deputy Director of the Agriculture Committee of the China Democratic League Central Committee，and the Deputy Chairman of the Shaanxi Provincial Committee of the China Democratic League. Moreover, he holds the post of vicepresident of the Shaanxi Provincial Association of Knowledge, an advisory expert to the Shaanxi Provincial People's Congress Standing Committee, and the director of the China Democratic League Yangling Demonstration Zone's working committee.

Ⅱ. Research interests

Genetic improvement of beef and dairy cattle; Biotechnology breeding and healthy aquaculture; Regulation of animal growth and development; Conservation of biodiversity.

Ⅲ. Projects in Research

1. National Natural Science Foundation of China, Screening and functional analysis of key long non-coding RNA (LncRNA) influenced intramuscular fat deposition of Qinchuan cattle (31972994).

2. CARS of Ministry of Agriculture and Rural Affairs and the Ministry of Finance, National Beef yak industry technology system (CARS-37).

3. The Ministry of Science and Technology and the Ministry of Finance guide the local special project, Qinchuan beef cattle efficient breeding and healthful aquaculture technology innovation and demonstration (2060404-51301).

4. Shaanxi Province key research and development program, Qinchuan cattle whole genome selection technology system (2022ZDLNY01-01).

5. Forestry Science and Technology Innovation Program of Shaanxi Province, Genetic code analysis, germplasm evaluation and protection of "Four Treasures of the Qinling Mountains" (SXLK2021-0102).

Ⅳ. Major Achievements

(Ⅰ) Major prize-winning achievements

1. Research on the supporting technology system of high-quality and efficient industrialization of Qinchuan cattle, the first Prize of Shaanxi Science and Technology Award in 2004, No.1

2. Research integration and demonstration of key technologies in the dairy Industry, the First Prize in the Shaanxi Science and Technology Award, the first prize in 2006

3. Key technology research and industrialization demonstration of breeding and crossbreeding of new Qinchuan beef cattle, the First Prize of Shaanxi Science and Technology Award in 2010, No.1

4. Research and demonstration of supporting technology system of high quality and efficient industrialization of dairy cows, the First Prize of China Agricultural Science and Technology Award of Ministry of Agriculture in 2011, No.1

5. Qinchuan beef cattle standardized production technology research integration demonstration promotion, the First Prize of Shaanxi Province Agricultural Technology Promotion Achievement Award in 2014, No.1

6. The genetic improvement and germplasm innovation team of beef cattle and dairy cattle, the Excellent Innovation Team Award of China Agricultural Science and Technology Award of the Ministry of Agriculture (equivalent to the first prize of Science and Technology) in 2015, No.1

7. Research integration and demonstration application of key technology of cow sex control, the First Prize of Shaanxi Science and Technology Award in 2016, No.1

8. Research integration, demonstration, and promotion of key technologies in standardized production of high-quality beef cattle, the first Prize of the National Harvest Award for Agriculture, Animal Husbandry and Fishery in 2019, No.1

9. Discovery of important genes for economic traits, development of molecular markers, and breeding application of Chinese yellow Cattle, First Prize of Shaanxi Science and Technology Award in 2014, No.3

10. The research and practice of the new mode of open education combined with production, education, and research, the Special Prize of Shaanxi Provincial Teaching Achievement Award, the fourth place in 2001, No.4

(Ⅱ) Representative works

1. Zan Linsen, editor-in-chief, Bovine Production (3rd Edition), China Agriculture Press, December 2017

2.Zan Linsen,editor-in-chief, Research on Genetic Diversity and Molecular Cell Engineering Breeding of Cattle in China, Northwest A&F University Press, November 2015

3. Zan Linsen, editor-in-chief, an Advanced Beef Production Technology Manual, China Agriculture Press, December 2017

4. Zan Linsen, editor-in-chief, Animal Science Specialty English, China Agriculture Press, July 2012

5. Zan Linsen and Li Bincheng, editor-in-chief, Chinese Cattle Culture, China Agriculture Press, July 2012

6. Zan Linsen, Xin Yaping, and Tian Wanqiang, editor-in-chief, 600 New Beef Cattle Feed Formulations (2nd Edition), Chemical Industry Press, January 2017

7. Zan Linsen, editor-in-chief, Theory and Practice of Breeding and Improvement of Qinchuan Cattle, Northwest A&F University Press, December 2007

8. Zan Linsen, editor-in-chief, Practical Technical Manual on High-Yield Dairy Cattle Breeding, China Agriculture Press, July 2005

9. Zan Linsen, editor-in-chief, Qin Chuan cattle, China Agriculture Press, January 2020

10. Zan Linsen, editor-in-chief, Regulation of Animal Growth and Development, China Agriculture Press, November 2020

(Ⅲ) Representative papers

1. Mei, C., Wang, H., Liao, Q., Wang, L., Cheng, G., Wang, H., ... Zan, L.* (2018) Genetic architecture and selection of Chinese cattle revealed by whole genome resequencing. Molecular Biology and Evolution, 35: 688-699

2. Li, A., Yang, Q., Li, R., Dai, X., Cai, K., Lei, Y., ... & Zan, L.* (2022). Chromosome‐level Genome Assembly for Takin (Budorcas taxicolor) Provides Insights into Its Taxonomic Status and Genetic Diversity.Molecular Ecology. mec.16483.

3. Yang, X., Mei, C., Raza, S. H. A., Ma, X., Wang, J., Du, J., & Zan, L.* (2022). Interactive regulation of DNA demethylase gene TET1 and m6A methyltransferase gene METTL3 in myoblast differentiation. International Journal of Biological Macromolecules, 223, 916-930.

4. Luoreng, Z., Wang, X., Mei, C. & Zan, L.* (2018) Comparison of microRNA profiles between bovine mammary glands infected with staphylococcus aureus and Escherichia coli. International Journal of Biological Sciences, 14: 87-99.

5. Yang, X., Ma, X., Mei, C., & Zan, L. * (2022). A genome-wide landscape of mRNAs, lncRNAs, circRNAs and miRNAs during intramuscular adipogenesis in cattle. BMC genomics, 23(1), 1-16.

6. Mei, C. G., Gui, L. S., Wang, H. C., Tian, W. Q., Li, Y. K., & Zan, L. S.* (2018). Polymorphisms in adrenergic receptor genes in Qinchuan cattle show associations with selected carcass traits. Meat science, 135, 166-173.

7. Mei, C., Wang, H., Liao, Q., Khan, R., Raza, S. H. A., Zhao, C., ... & Zan, L.* (2019). Genome-wide analysis reveals the effects of artificial selection on production and meat quality traits in Qinchuan cattle. Genomics, 111(6), 1201-1208.

8. Zhang, W., Sun, B., Zhao, Y., Raza, S. H. A., Li, Y., Wang, J., ... & Zan, L.* (2022). Proliferation of bovine myoblast by LncPRRX1 via regulation of the miR-137/CDC42 axis. International Journal of Biological Macromolecules, 220, 33-42.

9. Yang, X., Wang, J., Ma, X., Du, J., Mei, C., & Zan, L.* (2021). Transcriptome-wide N 6-Methyladenosine Methylome Profiling Reveals m6A Regulation of Skeletal Myoblast Differentiation in Cattle (Bos taurus). Frontiers in Cell and Developmental Biology, 9:1-10.

10. Wei, D., Li, A., Zhao, C., Wang, H., Mei, C., Khan, R. & Zan, L.* (2018) Transcriptional regulation by CpG sites methylation in the core promoter region of the bovine SIX1 gene: roles of histone H4 and E2F2. International Journal of Molecular Sciences, 19: 213.

Ⅴ. Team and platform

Based on Prof. Zan’s recommendation and declaration, his team won the title of the "Genetic Improvement and Germplasm Innovation Team for Beef Cattle and Dairy Cattle" and "Genetic Improvement and Biotechnology Breeding Innovation Team for Beef Cattle." And have been supported by "The Changjiang Scholars and Innovation Team Development Program of the Ministry of Education" and the "National Agricultural Research Outstanding Talents and Innovation Team Support Program" of the Ministry of Agriculture. The research team comprises twenty-two scientific and educational personnel, including eight professors, twelve associate professors, and two lecturers or research assistants. It was recognized as the excellent innovation team of the Ministry of Agriculture in 2015.

The team predominantly tends to rely on the National Beef Cattle Improvement Center, the National and Local Joint Engineering Research Center of Modern Cattle Biotechnology and Application, the Key Open Laboratory of Animal Biotechnology of the Ministry of Agriculture, the Yellow Cattle Research Laboratory of the Ministry of Agriculture, and Shaanxi Beef Cattle Engineering Technology Research Center. Except for that, the team relies on the Shaanxi Modern Cattle Engineering Research Center, Shaanxi Dairy Engineering Technology Research Center, Shaanxi High-quality Beef Production and Processing Project Technology Research Center, Shaanxi Province Qinchuan Beef Cattle Breeding Center, Western High-end Beef Cattle Industry Development Research Institute, Yichuan Beef Cattle Industry Research Institute and other platforms.

Ⅵ. Contact information

Postal address: College of Animal Science and Technology, Northwest A&F University, No. 22, Xinong Road, Yangling, Shaanxi, 712100

Contact number: 029-87091148, 87091248

Email: zanlinsen@163.com