JianHong Hu

　　 　　

Personal Resume: 

Jian-Hong Hu, Male, Born in January 1969, Bai Shui County of Shaanxi province, P.R. China, Han nationality; PhD, professor of animal science, doctoral supervisor of animal genetics breeding and reproduction professional, and zoology professional of Northwest A & F University. I also serve as executive director of the Reproduction Branch of the Chinese Animal Husbandry and Veterinary Medical Association, chief scientist of the Modern Beef Cattle Industry Technology System of Shaanxi Province, and director of the Third Council of the Shaanxi Provincial Animal Husbandry Association, among other professional organizations.

Education and work:

B.S. Northwestern Agriculture University, Animal Husbandry 1993

M.S. Northwest Agriculture & Forestry University, Animal Genetics Breeding and Reproduction 2002

Ph.D. Northwest A&F University, Animal Genetics Breeding and Reproduction 2006

From 2006 to now, I have been engaged in the research of animal genetics, breeding and reproduction in Northwest A & F University

Teaching:

● Livestock reproduction: cattle artificial insemination. 1993 to present

● Livestock production: cattle, sheep, swine and chicken production. 1993 to 2002

● Forage grass production: silage and alfalfa. 2000 to 2005

● Animal reproduction: cattle and swine. 2005 to present

● Biological statistics: 2005 to present

Courses:

●Undergraduate courses: Animal Reproduction, Biological Statistics, Animal Biology

●Graduate courses: Animal Reproduction Technology, Animal Reproductive Physiology

Research Interests: My research focuses on animal reproductive physiology and control technology, and animal biotechnology. In recent years, I have presided over 20 projects, including the National Natural Science Foundation of China, the National Transgenic Special Project, the National Key R&D Program, and the Shaanxi Provincial Key R&D Program.A primary focus is farm animal semen freezing,animal sex control technology, in vitro fertilization and embryonic development, spermatogonial stem cells inducing differentiating and transgenic animals，relationship between sertoli cell function and spermatogenesis.

Research Results and Awards:I have published more than 60 research articles , and I have applied for 13 patents and participated to write 18 books. In addition, I won the Silver Prize in the 2019 FENGDONG Cup Shaanxi Provincial Science and Technology Workers' Innovation and Entrepreneurship Competition, the First Prize in the 2020 FENGDONG Cup Shaanxi Provincial Science and Technology Workers' Innovation and Entrepreneurship Competition, the only Chinese finalist team in the Green Tech startup category of the 2020 World Cup of Entrepreneurship Global Finals, the Second Prize in the 2021 Shaanxi Provincial Science and Technology Workers' Innovation and Entrepreneurship Competition, and the Third Prize in the Innovation and Entrepreneurship Category of the 2022 National University Students' Life Science Competition, among other prizes.My doctoral dissertation of study on cryopreservation of boar semen had won outstanding paper award by Shaanxi Province in 2008. I have also accepted 5 honorary titles, including 4 outstanding teachers’ honorary titles of College of Animal Science and Technology, Northwestern A & F University.

Publications:

[1]Li Q, Shaoyong W, Li Y, Chen M, Hu Y, Liu B, Yang G, Hu J. Effects of oligomeric proanthocyanidins on quality of boar semen during liquid preservation at 17 °C. Anim Reprod Sci. 2018,198:47-56.

[2]Ren F, Feng T, Dai G, Wang Y, Zhu H, Hu J. Lycopene and alpha-lipoic acid improve semen antioxidant enzymes activity and cashmere goat sperm function after cryopreservation. Cryobiology. 2018,84:27-32.

[3]Dai GC, Meng Y, Zhang LK, Du YQ, Wen F, Feng TY, Hu JH. Effect of addition of melatonin on liquid storage of ram semen at 4°C. Andrologia. 2019,51:e13236.

[4]Xi H, Ren F, Zhang X, Li Y, Zhang L, Wen F, Feng T, Zhang X, Niu T, Hu J, Wang P. Trehalose protects testicular tissue of dairy goat upon cryopreservation. Reprod Domest Anim. 2019,54:1552-1559.

[5]Ren F, Fang Q, Feng T, Li Y, Wang Y, Zhu H, Hu J. Lycium barbarum and Laminaria japonica polysaccharides improve Cashmere goat sperm quality and fertility rate after cryopreservation.Theriogenology. 2019,15(129):29-36.

[6]Feng TY, Lv DL, Zhang X, Du YQ, Yuan YT, Chen MJ, Xi HM, Li Y, Han N, Hu JH. Rosmarinic acid improves boar sperm quality, antioxidant capacity and energy metabolism at 17°C via AMPK activation. Reprod Domest Anim. 2020,55:1714-1724.

[7]Ren F, Fang Q, Xi H, Feng T, Wang L, Hu J. Platelet-derived growth factor-BB and epidermal growth factor promote dairy goat spermatogonial stem cells proliferation via Ras/ERK1/2 signaling pathway. Theriogenology. 2020,155:205-212.

[8]Feng TY, Li Q, Ren F, Xi HM, Lv DL, Li Y, Hu JH. Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway. Oxid Med Cell Longev. 2020,2020:5954635.

[9]Ren F, Xi H, Ren Y, Li Y, Wen F, Xian M, Zhao M, Zhu D, Wang L, Lei A, Hu J. TLR7/8 signalling affects X-sperm motility via the GSK3 α/β-hexokinase pathway for the efficient production of sexed dairy goat embryos [J]. J Anim Sci Biotechnol, 2021, 12: 89.

[10]Xi H, Ren F, Li Y, Xian M, Wang L, Hu J. FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells [J]. Mol Cell Endocrinol, 2022, 540: 111505.

[11]Xi H M, Ren Y J, Ren F, Li Y, Feng T Y, Wang Z, Du Y Q, Zhang L K, Hu J H. Recent advances in isolation, identification, and culture of mammalian spermatogonial stem cells [J]. Asian J Androl, 2022, 24: 5-14.

[12]Ren F, Xi H, Qiao P, Li Y, Xian M, Zhu D, Hu J.Single-cell transcriptomics reveals male germ cells and Sertoli cells developmental patterns in dairy goats[J]. Front Cell Dev Biol, 2022, 10:944325.

[13]Xi H, Hu Z, Han S, Liu X, Wang L, Hu J. FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway [J]. Theriogenology, 2023, 195: 103-114.

[14]Lv D, Zhao M, Ni J, Liu W, Ren Y, Zhu D, Hu J. NGF regulates sertoli cell growth and prevents LPS-induced junction protein damage via PI3K/AKT/NFκB signaling [J]. Theriogenology, 2023, 195: 138-148.

[15]Liu X, Xi H, Han S, Zhang H, Hu J. Zearalenone induces oxidative stress and autophagy in goat Sertoli cells[J]. Ecotoxicol Environ Saf, 2023, 252:114571.

[16]Wen F, Liu W, Li Y, Zou Q, Xian M, Han S, Zhang H, Liu S, Feng X, Hu J. TLR7/8 agonist (R848) inhibit bovine X sperm motility via PI3K/GSK3α/β and PI3K/NFκB pathways[J]. Int J Biol Macromol, 2023, 232:123485.

[17]Han S, Zhang H, Liu X, Wen F, Li B, Bie Z, Qiu H, Hu J. Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat Sertoli cells[J]. Ecotoxicol Environ Saf, 2023, 259:115063.

[18]Zhang X, Guo SM, Zhu DW, Li Y, Wen F, Xian M, Hu ZT, Zou QL, Zhang LK, Chen YL, Hu JH. Metformin improves sheep sperm cryopreservation via vitalizing the AMPK pathway[J]. Theriogenology,2023, 208:60-70.