Ningbo Chen

　　 　　

Ningbo Chen, Ph.D.

Current Position: Associated Professor at College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100 China

E-mail: ningbochen@nwafu.edu.cn; Tel: +86 18700595957

DOB: December 15, 1987

ACADEMIC FORMATION

June 2019. Ph.D. degree in Animal genetics and breeding, Northwest A&F University.

July 2019. Associate Professor, College of Animal Science and Technology Northwest A&F University.

Aug 2020. Postdoctoral Fellow, College of Animal Science and Technology Northwest A&F University.

RESEARCH AREA

Cattle Population Omics/ Bovine Genetics/ Molecular Evolution/ Bioinformatics/

My research provides fundamental insight into the origin of cattle, genome organization and plasticity of farm animals, thereby improving our understanding of the molecular-genetic underpinnings of complex traits and diseases. Focus on to dissect genetic architecture of bovine populations, including cattle, yak, and other wild bovine species, quantitatively characterize their admixture features, and reveal their migration history and adaptive divergence. Using next generation sequencing, mitochondrial and the nuclear genome of both ancient and modern bovine species to reveal the population evolution and adaptive introgression.

The four main research foci include

[1]genome assembly and pangenome integration of Chinese cattle,

[2]the origin and formation of East Asian bovine species, including cattle, yak, aurochs, using ancient and modern DNA technology

[3]the genetic characterization of cattle adaptation to extremely environments, and

[4]population-scale complex trait genomics using omics data.

EDITORIAL AND REVIEWER ACTIVITY

Editorial Board of BMC Biology, BMC Genomics and BMC Genomic Data, Journal of Integrative Agriculture, Journal of Genetics and Genomics, Animal Research and One Health, Agriculture Communications, Modern Agriculture.

The reviewer activity carried out refers to iScience, Journal of Animal Breeding and Genetics, Animal Genetics, Genetic Selection Evolution, BMC Ecology and Evolution, Journal of Archaeological Science: Reports.

AWARDS

2020 Technology New Star in Shaanxi province, China

2020 Reward-gainers of the excellent PhD dissertations in Shaanxi Province, China

PUBLICATIONS

Selected publications from peer-reviewed journals, * stands for Corresponding author

[1]Fengwei Zhang#, Chong Wang#, Haiyue Xu#, Xiaoting Xia, Xiaoyu Luo, Kaihui Li, Jianlin Han, Chuzhao Lei*, Ningbo Chen*, Xiangpeng Yue*. (2023) Genomic analysis reveals a KIT-related chromosomal translocation associated with the white coat phenotype in yak. Journal of Animal Breeding and Genetics. 140(3):330-342.

[2]Xiaoting Xia, Kaixing Qu, Yan Wang, Mikkel‑Holger S. Sinding, Fuwen Wang, Quratulain Hanif, Zulfqar Ahmed, Johannes A. Lenstra, Jianlin Han, Chuzhao Lei* and Ningbo Chen*. (2023) Global dispersal and adaptive evolution of domestic cattle: a genomic perspective. Stress Biology. (2023) 3:8.

[3]Yuqing Han#, Lulan Zeng#, Shuang Li, Gaoxiang Yuan, Ying Liu, Xuhong Ding, Kaixing Qu, Fuqiang Li, Jicai Zhang, Chuzhao Le, Bizhi Huang*, Ningbo Chen*. (2021) T2R12 gene variation in Chinese native cattle owing to banteng introgression. Animal Genetics,52(4):565-566.

[4]Xiao-Ting Xia, Alessandro Achilli, Johannes A. Lenstra, Bin Tong, Yun Ma, Yong-Zhen Huang, Jian-Lin Han, Zhou-Yong Sun, Hong Chen, Chu-Zhao Lei1, Song-Mei Hu*, Ning-Bo Chen*. (2021) Mitochondrial genomes from modern and ancient Turano-Mongolian cattle reveal an ancient diversity of taurine maternal lineages in East Asia. Heredity, 126(6):100-1008.

[5]Chen, Ningbo#; Ren, Lele#; Du, Linyao#; Hou, Jiawen#; Mullin, VictoriaE.; Wu, Duo; Zhao, Xueye; Li, Chunmei; Huang, Jiahui; Qi, Xuebin; Capodiferro, Marco Rosario; Achilli, Alessandro; Lei, Chuzhao; Chen, Fahu; Su, Bing*; Dong, Guanghui*; Zhang, Xiaoming*. (2020) Ancient genomes reveal tropical bovid species in the Tibetan Plateau contributed to the prevalence of hunting game until the late Neolithic. Proceedings of the National Academy of Sciences, 2020, 117(45): 28150-28159.

[6]Chen, Ningbo#; Fu, Weiwei#; Zhao, Jianbang; Shen, Jiafei; Chen, Qiuming; Zheng, Zhuqing; Chen, Hong; Sonstegard, Tad S.; Lei, Chuzhao; Jiang, Yu*. (2020) BGVD: Integrated Web-database for Bovine Sequencing Variations and Selective Signatures. Genomics, Proteomics & Bioinformatics. 2020, 18(2): 186-193.

[7]Chen Ningbo#; Cai Yudong#; Chen Qiuming#; Li Ran#; Wang Kun#; Huang Yongzhen#; Hu Songmei; Huang Shisheng; Zhang Hucai; Zheng Zhuqing; Song Weining; Ma Zhijie; Ma Yun; Dang Ruihua; Zhang Zijing; Xu Lei; Jia Yutang; Liu Shanzhai; Yue Xiangpeng; Deng Weidong; Zhang Xiaoming; Sun Zhouyong; Lan Xianyong; Han Jianlin; Chen Hong; Bradley Daniel G; Jiang Yu*; Lei Chuzhao*. (2018) Whole-genome resequencing reveals world-wide ancestry and adaptive introgression events of domesticated cattle in East Asia. Nature Communications 9.

[8]Chen Ningbo#; Huang Jieping#; Zulfiqar Abbasi; Li Ran; Xi Yulian; Zhang Mingming; Dang Ruihua; Lan Xianyong; Chen Hong; Ma Yun; Lei Chuzhao*. (2018) Population structure and ancestry of Qinchuan cattle. Animal Genetics 49, 246-8.

[9]Han Haoyuan#, Chen Ningbo#, Jordi Jordana, Li C., Sun Ting, Xia Xiaoting, Zhao X, Ji C, Shen S, Yu Jie, Ainhoa F., Chen Hong, Lei Chuzhao; Dang Ruihua*. (2017) Genetic diversity and paternal origin of domestic donkeys. Animal Genetics 48, 708-11.

[10]Wang Shaoqiang#; Chen Ningbo#; Capodiferro Marco Rosario#; Zhang Tao; Lancioni Hovirag; Zhang Hucai; Miao Yongwang; Chanthakhoun V; Wanapat Metha; Yindee Marnoch; Zhang Yi; Lu Hongzhao; Caporali Leonardo; Dang Ruihua; Huang Yongzhen; Lan Xianyong; Plath Martin; Chen Hong; Lenstra Johannes A; Achilli Alessandro*; Lei Chuzhao*. (2017) Whole Mitogenomes Reveal the History of Swamp Buffalo: Initially Shaped by Glacial Periods and Eventually Modelled by Domestication. Scientific Reports 7.

[11]Chen Ningbo#; Ma Yun#*; Yang Ting#; Lin Fen; Fu Weiwei; Xu Yongjie; Li Fen; Li Junya; Gao Shuxin. (2015) Tissue expression and predicted protein structures of the bovine ANGPTL3 and association of novel SNPs with growth and meat quality traits. Animal 9, 1285-97.

[12]Ma Yun#*; Chen Ningbo#; Li Fen; Fu Weiwei; Han Yapeng; Chang Yanlin; Jiang Xiangxiang; Li Junya; Bai Yueyu; Tan Xuxin. (2015) Bovine HSD17B8 gene and its relationship with growth and meat quality traits. Science Bulletin 60, 1617-21.

PRESENTATIONS

[1]Genomic landscape of Chinese cattle PAG Online Conference, June 24, 2022

[2]The tropical and Subtropical Adaptation and Genetic Diversity of Chinese Local Cattle Based on the Whole Genome Data Shenzhen PAG June 7, 2019