Xihong WANG

　　 　　

Dr. XihongWANG

Professional Title:Associate Professor

Research Field:Agriculture Genomics

Date of Birth:April 1983

Cell phone:+86 18189187881

Email:wxh@nwafu.edu.cnrebecca_830410@163.com

Address:College of Animal Science and Technology,

Northwest A & F University, Yangling, China, 712100

EDUCATION and WORKING

2018 - presentAssociate Professor, College of Animal Science andTechnology,

Northwest A & F University

2013-2018Lecturer, College of Animal Science andTechnology,

Northwest A & F University

2012Embryologist, Monash IVF, Australia

2006 -2011Ph.D., Kunming Institute of Zoology, Chinese Academy of Sciences

2002-206B.Sc. of Biotechnology, Ocean University of China

RESEARCH INTERESTS

My research interests are on analysis the big agricultural omics data to uncover the genetic diversity, evolution and function in livestock. Using population genetics and bioinformatics,we analyzed the livestock genome big data, including wild, ancient and related species. The results revealed the key traits in domestication and selection, such as tameness, parasite resistance and cashmere production and related genes. Besides we optimized the algorism and detected the CNVs inlivestock. The research results were published in "Science Advances", "Molecular Biology and Evolution" and so on.

GRANTS

PI of the project “Functional study of large fragment deletion in goat BMPR1B gene in litter size”,￥0.24 million, funded by the National Natural Science Foundation of China (2020-2022)

Co-PI of the project "The Pan Caprinae Genome Plan",￥0.5 million, funded byNorthwest A & F University(2016-2020)

Co-PI of the project “Evolutionary genomics analysis in Oula-type Tibetan sheep: findingthe genes underlying high-altitude adaptation”,￥0.77 million, funded by the National Natural Science Foundation of China (2016-2019)

PI of the project " Screening of key mutations for plateau adaptation in Tibetan sheep ",￥50 thousand, funded by Northwest A & F University(2016-2020)

PI of Start up Founds,￥50 thousand,funded by Northwest A & F University, China (2014-2016)

Main PUBLICATIONS

(#first author, *corresponding author)

1. Dou M#, Li M#, Zheng Z#, Chen Q, Wu Y, Wang J, Shan H, Wang F, Dai X, Li Y, Yang Z, Tan G, Luo F, Chen L, Shi YS, Wu JW, Luo XJ, Asadollahpour Nanaei H, Niyazbekova Z, Zhang G, Wang W, Zhao S*, Zheng W*, Wang X*, Jiang Y*. A missense mutation in RRM1 contributes to animal tameness. Sci Adv. 2023 Jun 23;9(25):eadf4068. doi: 10.1126/sciadv.adf4068. Epub 2023 Jun 23. PMID: 37352351; PMCID: PMC10289655.

   Asadollahpour Nanaei H#, Cai Y#, Alshawi A, Wen J, Hussain T, Fu WW, Xu NY, Essa A, Lenstra JA, Wang X*, Jiang Y*. Genomic analysis of indigenous goats in Southwest Asia reveals evidence of ancient adaptive introgression related to desert climate. Zool Res. 2023 Jan 18;44(1):20-29. doi: 10.24272/j.issn.2095-8137.2022.242. PMID: 36257823; PMCID: PMC9841177.

   Yang ZR#, Li JX#, Zheng ZQ, Zhao C, Wang Y, Li M, Nanaei HA, Dai XL, Li YJ, Li R, Cao CN, Li M, Jiang Y*, Zheng WX*, Wang XH*. Allele-specific expression analyses reveal immune divergences between ibex and goat species. Zool Res. 2022 Jul 18;43(4):671-674. doi: 10.24272/j.issn.2095-8137.2022.003. PMID: 35791614; PMCID: PMC9336447.

   Cai Y#, Fu W#, Cai D#, …et al., Jiang Y*, Wang X*, Ancient genomes reveal the evolutionary history and origin of cashmere producing goats in China, Molecular Biology and Evolution.2020,1,37(7):2099-2109. (cover story)

   Zheng Z#, Wang X#, Li M#, Li Y#, Yang Z#, Wang X#, …et al., Chen Y*, Jiang Y*, The origin of domestication genes in goat, Science Advances. 2020, 6(21). (cover story)

   Wang X#, Zheng Z#, …et al., Jiang Y*, CNVcaller: Highly Efficient and Widely Applicable Software for Detecting Copy Number Variations in Large Populations, GigaScience, 2017, 6(12): 1-12

   Huang Y#, Li Y#, Wang X#, Yu J#, …et al., Jiang Y*. An atlas of CNV maps in cattle, goat and sheep. Sci China Life Sci. 2021

   Jiang Y#, Wang X#, …et al., Dalrymple BP *, Beta-globin gene evolution in the ruminants: evidence for an ancient origin of sheep haplotype B, Animal Genetics, 2015, 46(5): 506-514