Qihang Hou

　　 　　

1. Basic Information

Qihang Hou, PHD degree.

The College of Animal Science and Technology, Northwest A&F University, associate professor.

Email: qihanghou1992@163.com

2. Research Direction

My primary research focuses on the inflammatory mechanisms and nutritional regulation of immune responses in the gastrointestinal tracts of livestock and poultry. Utilizing a combination of various techniques including cell biology, molecular biology, and omics analyses, I investigate the immunological mechanisms by which the gastrointestinal tracts of livestock and poultry defend against infections caused by pathogenic microorganisms, as well as the mechanisms underlying the healing of inflamed intestinal mucosa.

3. Publication

1. Qihang Hou+, Lulu Ye+, et al. The Reseach Progress on Intestinal Stem Cells and Its Relationship with Intestinal Microbiota [J]. Front Immunol. 2017 May 23;8:599.

2. Qihang Hou, et al. Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22[J]. Cell Death Differ. 2018 Sep;25(9):1657-1670.

3. Qihang Hou+, Yuanyang Dong+, et al. Regulation of the Paneth cell niche by exogenous L-arginine couples the intestinal stem cell function [J]. FASEB J. 2020 Jun 17.

4. Qihang Hou, et al. Exogenous L-arginine increases intestinal stem cell function through CD90+ stromal cells producing mTORC1-induced Wnt2b[J]. Commun Biol. 2020 Oct 23;3(1):611.

5. Qihang Hou, et al. Intestinal Stem Cells and Immune Cell Relationships: Potential Therapeutic Targets for Inflammatory Bowel Diseases[J]. Front Immunol. 2021 Jan 20;11:623691.

6. Qihang Hou+,Junpeng Jia+,et al. Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection[J]. Cell Reports. 2022. 111416.

7. Qihang Houet al. Role of Nutrient-sensing Receptor GPRC6A in Regulating Colonic Group 3 Innate Lymphoid Cells and Inflamed Mucosal Healing[J]. J Crohns Colitis. 2022 Aug 30;16(8):1293-1305.

8. Qihang Houet al. Dietary genistein increases microbiota-derived short chain fatty acid levels, modulates homeostasis of the aging gut, and extends healthspan and lifespan[J]. Pharmacological Research. 2023 Feb;188:106676.

9. Youli Wang, Qihang Hou et al. Methionine deficiency and its hydroxy analogue influence chicken intestinal 3-dimensional organoid development[J]. Animal Nutrition. 2022 Mar 8(1):38-51.

10. Guang Li, Yuqing Feng, Jian Cui, Qihang Hou, et al.The ionome and proteome landscape of aging in laying hens and relation to egg white quality[J]. Science China-Life Sciences. 2023Jul. 27.