Lei Gao

　　 　　

Lei Gao

College Animal Science & Technology, NW A&F Univ,

22 Xinong Rd, Yangling712100, Shaanxi, P. R. China

E-mail: gaolei5414@163.com

Work experience

2020-Present Northwest A&F University (Yangling, Shaanxi)

·Assistant Professor

College of Animal Science and Technology

Education

2015-2020 China Agricultural University (Beijing)

PhD degree

Advisor: Prof. Fu Xiangwei

Research Direction

Oocyte Vitrification

Spindle Assembly

Publications

1. Sun H#, Guo Y#, Yu R, Wang J, Liu Y, Chen H, Pang W, Yang G, Chu G#, Gao L*. Ru360 protects against vitrification-induced oocyte meiotic defects by restoring mitochondrial function. Theriogenology. 2023 Jul 1;204:40-49.

2. Yaoyao Guo#, Haowei Sun#, Hui Chen, Gongshe Yang, Jialun Wang, Zhengjun Qi, Weijun Pang, Guiyan Chu, Lei Gao*, Vitrification induces a focused spindle pole in mouse MI oocytes, Theriogenology, 2023

3. Huang L, Zhang L, Shi S, Zhou X, Yuan H, Song X, Hu Y, Pang W, Yang G, Gao L*, Chu G*. Mitochondrial function and E2 synthesis are impaired following alteration of CLOCK gene expression in porcine ovarian granulosa cells. Theriogenology. 2023 May;202:51-60.

4. Sheng-jie SHI, Lu-tong ZHANG, Li-guang WANG, Huan YUAN, Hao-wei SUN, Mielie MADANIYATI, Chuan-jiang CAI, Wei-jun PANG, Lei GAO*, Gui-yan CHU*. MicroRNA-24-3p promotes proliferation and inhibits apoptosis of porcine granulosa cells by targeting P27, Journal of Integrative Agriculture, 2023, ISSN 2095-3119.

5. Lei Gao, Yunpeng Hou, Shenming Zeng, Junyou Li, Shien Zhu, Xiangwei Fu*. 2020. The Error-Prone Kinetochore-Microtubule Attachments During Meiosis I in Vitrified Oocytes. Front Cell Dev Biol. 8: 621.

6. Lei Gao#, Gongxue Jia#, Zhengyuan Huang, Mingxing Yue, Chao Zhang, Shien Zhu, Yunpeng Hou, Xiangwei Fu*. 2020. Effect of Aging on Meiosis Progression, Developmental Competence and DNA Double-Strand Breaks in Mouse Oocytes. Pak J Zool. 52(4), 1463-1470.

7. Lei Gao#, Ming Du#, QingruiZhuan,Yuxi Luo , Junyou LI, Yunpeng Hou, Shenming Zeng, Shien Zhu, Xiangwei Fu*. 2019. Melatonin rescues the aneuploidy in mice vitrified oocytes by regulating mitochondrial heat product. Cryobiology, 89, 68-75.

8. Lei Gao#, Gongxue Jia#, Ai Li, Haojia Ma, Zhengyuan Huang, Zhu, Yunpeng Hou, Shien Zhu, Xiangwei Fu*. 2017. RNA-Seq transcriptome profiling of mouse oocytes after in vitro maturation and/or vitrification. Sci Rep, 7(1), 13245.

9. Jiao JH#, Gao L#, Yong WL, Kou ZY, Ren ZQ, Cai R, Chu GY, Pang WJ*. Resveratrol improves estrus disorder induced by bisphenol A through attenuating oxidative stress, autophagy, and apoptosis. J Biochem Mol Toxicol. 2022 Sep;36(9):e23120.

10. Lihong Zhao, Tengfei Lu, Lei Gao, Xiangwei Fu, Shien Zhu, Yunpeng Hou*. 2017. Enriched endoplasmic reticulummitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice. J Anim Sci Biotechno, 8:62.

11. Zhengyuan Huang#, Jinghao Liu#, Lei Gao, Qingrui Zhuan, Yuxi Luo, Shien Zhu, Kaiyu Lei, Xiangwei Fu*. 2018. The impacts of laser zona thinning on hatching and implantation of vitrified-warmed mouse embryos. Laser Med Sci. 34 (5): 939-945.

12. Qingrui Zhuan#, Haojia Ma#, Jing Chen#, Yuxi Luo, Yan Luo, Lei Gao, Yunpeng Hou, Shien Zhu, Xiangwei Fu*. 2020. Cytoplasm lipids can be modulated through hormone-sensitive lipase and are related to mitochondrial function in porcine IVM oocytes. Reprod Fert Develop. 32 (7): 667-675.