Zhongliang Jiang

　　 　　

Zhongliang Jiang

Title： Professor

Academic Title(s):  PH. D.

Contact Information:

Email: jiangzhongliang@nwafu.edu.cn

Current Address:

College of Animal Science and Technology, Northwest A&F University, NO.22, Xinong Road, Yangling, Shaanxi, China，712100

Research Direction:

The Role of Transzonal projections (TZPs) between Ovarian Granulosa Cells and Follicular Development and Atresia

The Effects of Environmental Factors (toxins) on Animal Reproduction

Animal Biotechnology of Embryonic Engineering

Founding Support:

National Natural Science Founding of China (NSFC, No. 32272880)

The Key Research and Development Program in Shaanxi Province, China (No. 2022 QFY12-05)

Website Link:

https://dkxy.nwsuaf.edu.cn/szdw/zjrc/900804e6baca4dd0a8c3c1c0eb43fff2.htm

Education Experience:

PhD. in Animal Genetic, Breeding and Reproduction (2010), Northwest Agricultural & Forestry University, China

M.S. in Animal Genetic, Breeding and Reproduction (2004), Northwest Agricultural & Forestry University, China

B.S. in Animal Nutrition and Reproduction (1998), Northwest Agricultural & Forestry University, China

Training:

2011-2013, Visiting postdoctoral fellow, Receptor Biology Group, Laboratory of Reproductive & Developmental Toxicology, National Institute of Environmental Health and Science, RTP, USA

Mentor: Dr. Kenneth S. Korach,  In Vitro  Growth of Follicles from Ovaries of Estrogen Receptor α AF-2 Mutant Mouse

2007-2009, Visiting PH.D. student in CRRA, Faculty of veterinary and medicine, University of Montreal, QC, Canada

Advisor: Prof. Christopher A. Price, Roles of FGFs on Sprouty Genes Expression in Bovine Ovarian Granulosa Cells      

Honors and Awards:

2019, Special prize for Agricultural Extension Cooperation, Ministry of Agriculture and Rural Affairs, China

2015, Beef cattle and dairy Cattle Genetic Improvement Innovation Cooperation Award, Ministry of Agriculture and Rural Affairs, China.

2013, Outstanding Paper Award, 17th Symposium of Chinese Animal Reproduction Society.

2009, USDA-CSREES-NATIONAL INTIATIVE MERIT AWARDS, the 42nd Annual Meeting of the Society for the Study of Reproduction, Pittsburgh, USA.

2009, Travel award to attend the Annual SSR Meeting, RQR, QC, Canada.

2007, Visiting Scholarship award, China Scholarship Council, China.

2002, Asian Agricultural Biological Scholarship for Excellent Undergraduate Students, China.

Presentation and Posters:

2023, Oral presentation, VD3 Promotes Autophagy of Porcine Ovarian Granulosa Cells. 21st Symposium of Chinese Animal Reproduction Society.

2023, Oral presentation, PHB2 induce autophagy of bovine ovarian granulosa cells. 21st Symposium of Chinese Animal Reproduction Society.

2019, Oral presentation, Protective effects of trehalose on ovarian granulosa cells of cattle. 20th Symposium of Chinese Animal Reproduction Society.

2017, Oral presentation, Role of Laminaria japonica polysaccharide 3 (LJP-P3) on bull sperm, 19th Symposium of Chinese Animal Reproduction Society.

2012, LRDT Fellows Summer Seminar Series, In Vitro Growth of Follicles from Ovaries of Estrogen Receptor α AF-2 Mutant Mouse, USA

2010, Oral presentation on Symposium of Animals Science, FGF2 regulated Sprouty genes expression by ERK/MAPK and AKT/PI3K pathway, Northwest A&F University, Shaanxi, China

2009, Oral presentation on Reproductive Biology Workshop, FGFs differentialy regulated sprouty expression in bovine granulosa cell, University of Ottawa, ON, Canada

2009, Poster on the 42nd SSR, FGFs Differentially Regulate Sprouty Expression and ERK Phosphorylation in Bovine Ovarian Granulosa Cells, Pittsburgh, USA

2008, Poster on the 1st RQR, Expression of Sprouty genes in bovine granulosa cells, Montreal, Canada

Selected publications:

Zhang Zelin*, Cheng Jianyong, Yang Li, Li Xiaoya, Hua Rongmao, Xu Dejun, Jiang Zhongliang#, Li Qingwang#. The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine-induce injury of BTB integrity. Free Radical Biology and Medicine. 2023, 200: 26-35. PMID:36893944

Wang Shiyou*, Yao Qichun, Zhao Fan, Cui Wenfei, Price Christopher, Wang Yifan, Lv Jing, Tang Hong, Jiang, Zhongliang#. 1 alpha,25(OH)(2)D-3 Promotes the Autophagy of Porcine Ovarian Granulosa Cells as a Protective Mechanism against ROS through the BNIP3/PINK1 Pathway. International Journal of Molecular Science. 2023, 24(5)4364. PMID:36901794

Guangyu Liu*, Yifan Wang, Yuxin Zheng, Jing Lv, Yuanyou Li, Ning Liu, Huimin Gao, Haohan Ran, Hong Tang, Zhongliang Jiang#. PHB2 binds to ERb to induce the autophagy of porcine ovarian granulosa cells through mTOR phosphorylation. Theriogenology. 2023,198 : 114-122. PMID: 36580849

Guangyu Liu*, Yuxin Zheng, Huimin Gao, Wenfei Cui, Fan Zhao, Ning Liu, Xiaorong Tang, Zhongliang Jiang#. Expression of ERβ induces bovine ovarian granulosa cell autophagy via the AKT/mTOR pathway. Reproduction in Domestic Animals. 2022;57:989–998. PMID: 35612957

Ning Liu*, Shiyou Wang, Qichun Yao, Yuanyou Li, Hai Hu, Xiaorong Tang, Haohan Ran, Christopher A. Price, Zhongliang Jiang#. Activin A attenuates apoptosis of granulosa cells in atretic follicles through ERβ- induced autophagy. Reproduction in Domestic Animals. 2022;57:625–634. PMID: 35244300

Xiaorong Tang*，Lizhu Ma，Shun Guo，Mingyue Liang，Zhongliang Jiang#. High doses of FSH induce autophagy in bovine ovarian granulosa cells via the AKT/mTOR pathway. Reproduction in Domestic Animals. 2021;56:324–332. PMID: 33247963

Lizhu Ma*，Xiaorong Tang, Shun Guo, Mingyue Liang, Bin Zhang, Zhongliang Jiang#. miRNA-21e3p targeting of FGF2 suppresses autophagy of bovine ovarian granulosa cells through AKT/mTOR pathway. Theriogenology 157 (2020) 226-237. PMID: 32818880

Lizhu Ma*, Yuxin Zheng, Xiaorong Tang, Huimin Gao, Ning Liu, Yan Gao, Lizhuang Hao, Shujie Liu and Zhongliang Jiang#. miR-21-3p inhibits autophagy of bovine granulosa cells by targeting VEGFA via PI3K/AKT signaling. Reproduction. (2019) 158 441–452. PMID: 31546232

Lizhu Ma*, Yuxin Zheng, Dingxin Jia, Nina Zhang, Shujie Liu, Liqiang Wang, Zhongliang Jiang#. Hypoxia limits the growth of bovine preantral follicles in vitro by inhibiting estrogen receptor α. Animals. 2019, 9, 551; doi:10.3390/ani9080551. PMID: 31412668

Nina Zhang*, Liqiang Wang, Guoya Luo, Xiaorong Tang, Lizhu Ma, Yuxin Zheng, Shujie Liu, Christopher A. Price and Zhongliang Jiang#. Arachidonic Acid Regulation of Intracellular Signaling Pathways and Target Gene Expression in Bovine Ovarian Granulosa Cells. Animals. 2019, 9, 374; doi:10.3390/ani9060374. PMID: 31248190

Y.X. Zheng*，L.Z. Ma，S.J. Liu，C.T. Zhang，R. Meng，Y.Z. Chen，Z.L. Jiang#. Protective effects of trehalose on frozen-thawed ovarian granulosa cells of cattle. Animal Reproduction Science. 200 (2019) 14–21. PMID: 30472065

Yuxin Zheng*，Lizhu Ma, Ning Liu, Xiaorong Tang, Shun Guo, Bin Zhang and Zhongliang Jiang#. Autophagy and Apoptosis of Porcine Ovarian Granulosa Cells During Follicular Development. Animals. 2019, 9, 1111; doi:10.3390/ani9121111. PMID: 31835576

Yuxin Zheng*, Nina Zhang, Shujie Liu, Qingwang Li, Zhongliang Jiang#. Effects of water-soluble Laminaria japonica polysaccharide 3 (LJP-P3) on bull cryopreservation sperm. Cryobiology 79 (2017) 50-55. PMID: 28941986

Zhongliang Jiang*, Hilda M. Guerrero-Netro, Jennifer L. Juengel, Christopher A. Price#. Divergence of intracellular signaling pathways and early response genes of two closely related fibroblast growth factors, FGF8 and FGF18, in bovine ovarian granulosa cells，Molecular and Cellular Endocrinology，375（2013），97-105. PMID: 23707615

Zhongliang Jiang* and Christopher A Price. Differential actions of fibroblast growth factors on intracellular pathways and target gene expression in bovine ovarian granulosa cells，Reproduction, 2012，144，625–632. PMID: 22956519

Z.L. JIANG*, P. RIPAMONTE, J. BURATINI, V.M. PORTELA, AND C.A. PRICE#. Fibroblast Growth Factor-2 Regulation of Sprouty and NR4A Genes in Bovine Ovarian Granulosa Cells. Journal of Cellular Physiology, 2011 (226) 1820–1827. PMID: 21506113