English

Gongshe Yang

1. Basic Information

Gongshe Yang, Professor

College of Animal Science and Technology

Northwest A&F University

Yangling, Shaanxi 712100 China

Phone: 029-87092430

Email: gsyang999@hotmail.com

2. Education and Work Experience

1982	B.A. in Animal Husbandry	Northwest Agricultural College
1985	M.A. in Animal Genetic and Breeding	Northwest Agricultural College
1993	Ph.D. in Animal Genetic and Breeding	Northwest A&F University
2006	Visiting Research	The University of Montreal
1985-Present	Prof. in Animal Genetic and Breeding	Northwest A&F University

Formerly served as a member of the 11th National Committee of the Chinese People's Political Consultative Conference, a member of the Discipline Evaluation Group of the 5th and 6th Academic Degrees Committees of the State Council, the Deputy Director of the Teaching Guidance Committee for Animal Production in Higher Education Institutions under the Ministry of Education, a representative of the 9th Shaanxi Provincial People's Congress, a member of the 9th Standing Committee of the Chinese People's Political Consultative Conference, a member of the Shaanxi Provincial Decision Advisory Committee, and the Dean of the School of Animal Science and Technology at Northwest A&F University. Exemplary individual of National Teacher Ethics, 2001.

Currently serving as a member of the National Agricultural Science Expert Consultation Group (973 Program), a member of the National Genetically Modified Pig New Variety Cultivation Major Special Execution Expert Group, a member of the National Pig Genetic Improvement Plan Expert Group, a member of the Pig Professional Committee of the National Livestock and Poultry Genetic Resources Committee, a scientist in the position of the National Pig Industry Technology System, Chairman of the Pig Breeding Association of the Five Northwest Provinces (Districts), and Editorial Committee Member of the《Chinese Journal of Biochemistry and Molecular Biology 》and the《Chinese Journal of Cell Biology》.

3. Research Interests

(1) Pig genetic improvement

(2) The molecular mechanism of fat deposition

(3) Regulation of muscle cell development and muscle fiber differentiation

4. Grants

The National Science and Technology Major Special Project of the Ministry of Science and Technology of China, Key Project of Chinese National Programs (973 Program), National Programs for High Technology Research and Development (863 Program), National Science and Technology Support Plan, National Natural Science Foundation of China, Modern Agriculture Industry Technology System of the Ministry of Agriculture, Shaanxi Province Major Science and Technology Innovation Special Project.

5. Representative Publications

Yi X, Cai R, Shaoyong W, Wang G, Yan W, He Z, Li R, Chao M, Zhao T, Deng L, Yang G*, Pang W*. Melatonin promotes gut anti-oxidative status in perinatal rat by remodeling the gut microbiome. Redox Biol. 2023 Sep; 65: 102829. (IF: 11.900)

Yu T, Tian X, Li D, He Y, Yang P, Cheng Y, Zhao X, Sun J, Yang G*: Transcriptome, proteome and metabolome analysis provide insights on fat deposition and meat quality in pig. Food Res Int 2023, 166:112550. (IF: 7.700)

Xiang Y, Huang R, Wang Y, Han S, Qin X, Li Z, Wang X, Han Y, Wang T, Xia B, Wu J, Yang G*. Protocatechuic Acid Ameliorates High Fat Diet-Induced Obesity and Insulin Resistance in Mice. Mol Nutr Food Res. 2023 Feb;67(3) (IF: 6.201)

Huang K, Jia Z, Li H, Peng Y, Chen X, Luo N, Song T, Wang Y, Shi X, Kuang S, Yang G*. Proto-oncogene FAM83A contributes to casein kinase 1-mediated mitochondrial maintenance and white adipocyte differentiation. J Biol Chem. 2022 Oct;298(10):102339. (IF: 4.800)

Mingle Dou, Ying Yao, Ying Peng, Meixue Xu, Xin’e Shi, Gongshe Yang, Xiao Li*. The long noncoding RNA MyHC IIA/X-AS contributes to skeletal muscle myogenesis and maintains the fast fiber phenotype. Journal of Biological Chemistry, 2020 Apr 10; 295(15):4937-4949. (IF: 4.800)

Mi L, Zhao XY, Li SM, Yang GS*, Lin JD*. Conserved Function of the Long Noncoding RNA Blnc1 in Brown Adipocyte Differentiation. Molecular Metabolism 2016 (IF: 5.363).

Yang H, Wu JW, Wang SP, Severi I, Sartini L, Frizzell N, Cinti S, Yang GS*, Mitchell GA*. Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis and Insulin Resistance. Diabetes 2016, 65(11): 3396-3409. (IF: 8.784).

Wang GQ, Wang Y, Xiong Y, Chen XC, Ma ML, Cai R, Gao Y, Sun YM, Yang GS, Pang WJ*. Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a. Scientific Reports, 2016, 6, srep21865: 1–13 (IF: 5.578).

Zhao CZ，Chen XC，Wu WJ， Pang WJ , Yang GS*. MAT2B promotes adipogenesis by modulating SAMe levels and activating AKT/ERK pathway during porcine intramuscular preadipocyte differentiation. Experimental cell research. 2016, 344(1):11-21 (IF: 3.246)

Zhu JY, Shi XE, Lu HZ, Xia B, Li YF, Li X, Zhang QL, Yang GS*. RNA-seq transcriptome analysis of extensor digitorum longus and soleus muscles in large white pigs. Molecular Genetics and Genomics, 2016, 291(2):11-21 (IF: 2.728)

Mi L, Chen YS, Zheng XL, Li YL, Zhang QL, Mo DL, Yang GS*. MicroRNA-139-5p suppresses 3T3‐L1 preadipocyte differentiation through notch and IRS1/PI3K/Akt insulin signaling pathways. Journal of Cellular Biochemistry, 2015, 116(7): 1195-1204 (IF: 3.263)

Lu H, Shi X, Wu G, Zhu J, Song C, Zhang Q, & Yang GS*. FGF13 regulates proliferation and differentiation of skeletal muscle by down‐regulating Spry1. Cell proliferation. 2015, 48(5):550–560 (IF: 3.116)

Cheng J, Li Y., Wu G, Zheng J, Lu H, & Yang GS*. Ectopic expression of RBP4 impairs the insulin pathway and inguinal fat deposition in mice. Journal of physiology and biochemistry, 2014,70(2), 479-486. (IF: 2.496)

Ji HL, Song CC, Li YF, He JJ, Li YL, Zheng XL, & Yang GS*. miR-125a inhibits porcine preadipocytes differentiation by targeting ERRα. Molecular and cellular biochemistry, 2014, 395(1-2), 155-165. (IF: 2.388)

Zhang ZY, Mai Y, Yang H, Dong PY, Zheng X L, & Yang GS *. CTSB promotes porcine preadipocytes differentiation by degrading fibronectin and attenuating the Wnt/β-catenin signaling pathway. Molecular and cellular biochemistry, 2014, 395(1), 53-64 (IF: 2.388)

Du B, Cawthorn W P, Su A, Doucette CR, Yao Y, Hemati N, Kampert S McCoin C, Broome DT, Rosen CJ, Yang GS*, MacDougald O. The transcription factor paired-related homeobox 1 (prrx1) inhibits adipogenesis by activating transforming growth factor-β (tgfβ) signaling. Journal of Biological Chemistry, 2013, 288 (5): 3036-3047 (IF: 4.600)

Luo X, Hutley LJ, Webster JA, Kim YH, Liu DF, Newell FS, Widberg CH, Bachmann A, Turner A, Carsten S, Prins JB, Yang GS*, Whitehead JP. Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors. Diabetes, 2012, 61(1): 124-136 (IF: 7.895)

Wu JW, Wang SP, Alvarez F, Casavant S, Gauthier N, Abed L, Soni KG, Yang GS*, Mitchell G A. Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis. Hepatology, 2011, 54(1): 122-132 (IF 11.665)

Bai L, Jia Y, Viswakarma N, Huang J, Vluggens A, Wolins NE, Jafari N, Sambasiva RM, Borensztagn J, Yang GS*, Reddy JK. Transcription coactivator mediator subunit MED1 is required for the development of fatty liver in the mouse. Hepatology, 2011, 53(4): 1164-1174 (IF: 11.665)