西北农林科技大学 动物科技学院
师资队伍
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王小龙

发布日期:2016-05-18 浏览次数:

  

  

  1.基本信息

  王小龙,男,1983年生于陕西陇县,副教授,硕士生导师。2005年和2008年分别在西北农林科技大学动物科技学院获本科和硕士学位。2013年获德国慕尼黑工业大学动物育种研究所自然科学博士学位。

  目前是中国畜牧兽医学会高级会员,国际动物遗传学会(ISAG)会员,兼任国际动物遗传学会羊应用遗传学专业委员会执委(Standing Committee)、基因编辑动物专业委员会执委,Reproduction, Fertility & Development副主编(Associate Editor),Journal of Animal Science编委(Editorial board),多个国内外期刊审稿人。

  入选“陕西省青年科技新星”(2017)和“西北农林科技大学仲英青年学者”(2016)。

  2.研究方向

  基于基因编辑技术的羊功能基因的精准编辑;羊经济性状功能基因的挖掘;山羊次级毛囊生长和发育调控机制。

  3.主讲课程

  主要承担《羊生产学》(本科生)及《动物遗传繁育进展》(研究生)等课程。

  4.主持科研项目

  (1)国家自然科学基金(面上项目、青年基金)。(在研)

  (2)中国博士后科学基金(特别资助、一等资助)。(在研)

  (3)陕西省青年科技新星资助。(在研)

  (4)陕西省重点研发计划(一般项目)(在研)

  (5)仲英青年学者资助。(在研)

  (6)陕西省留学归国人员配套资助项目。(在研)

  (7)教育部留学回国人员科研启动基金。(在研)

  (8)陕西省博士后项目资助。(在研)

  (9)中央高校基本科研业务费。(在研)

  (10)陕西省自然科学基金(面上项目)。(已结题,优秀)

  5.代表性学术论文

  Li Y, Zhou G, Zhang R, Guo J, Li C, Martin G, Chen Y, Wang X*. Comparative proteomic analyses using iTRAQ-labeling provides insights into fiber diversity in sheep and goats, Journal of Proteomics , (accepted) (*通讯作者)

  Wang X, Niu Y, Zhou J, Zhou H, Ma B, Yu H, Yan H, Hua J, Huang X, Qu L, Chen Y. CRISPR/Cas9-mediated MSTN disruption and heritable mutagenesis in goats causes increased body mass. Animal Genetics . (accepted)

  Niu Y, Zhao X, Zhou J, Li Y, Huang Y, Cai B, Liu Y, Ding Q, Zhou S, Zhao J, Zhou G, Ma B, Huang X, Wang X*, Chen Y*, Efficient generation of goats with defined point mutation (I397V) in GDF9 through CRISPR/Cas9, Reproduction. Fertility. Development . (2017).

  Wang X, Niu, Y, Zhou J, Yu H, Kou Q, Lei A, Zhao X, Yan H, Cai B, Shen Q, Zhou S, Zhu H, Zhou G, Niu W, Hua J, Jiang Y, Huang X, Ma B, Chen Y. Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep, Scientific Reports . 6 (2016).

  Zhao J, Liu S, Zhou X, Zhang R, Li Y, Wang X*, Chen Y*. A non-synonymous mutation in GDF9 is highly associated with litter size in cashmere goats. Animal Genetics . (2016).

  Wang X, Yu H, Lei A, Zhou J, Zeng W, Zhu H, Dong Z, Niu Y, Shi B, Cai B, Liu J, Huang S, Yan H, Zhao X, Zhou G, He X, Chen X, Yang Y, Jiang Y, Shi L, Tian X, Wang Y, Ma B, Huang X, Qu L, Chen Y. Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system. Scientific Reports 5 (2015). (他引38次)

  Wang X, Zhou G, Xu X, Geng R, Zhou J, Yang Y, Yang Z, Chen Y, Transcriptome profile analysis of adipose tissues from fat and short-tailed sheep. Gene 549, 252–257 (2014).

  Wang X, Wurmser C, Pausch H, Jung S, Reinhardt F, Tetens J, Thaller G, Fries R, 2012. Identification and dissection of four major QTL affecting milk fat content in the German Holstein-Friesian population. PLoS ONE 7, e40711. (2012). (他引55次)

  6.国际会议(交流)

  “Heritable multiplex gene editing via CRISPR/Cas9 exhibits no detectable genome-wide off-target effects in sheep”, 35th ISAG, 2016, Salt Lake City, USA (Oral Presentation)

  “Heritable gene disruption in goats with CRISPR/Cas9 results in expected phenotypes”, 35th ISAG, 2016, Salt Lake City, USA (Oral Presentation)

  “Multiplex genome editing in goats and sheep via the CRISPR/Cas9 system”, 3rd PAG ASIA. 2016, Singapore (Oral Presentation)

  “CRISPR/Cas9-mediated multiplex genome editing in goats and sheep”, The 2nd Beijing Sheep Forum, 2015, Urumqi, China (Oral Presentation)

  “Whole-genome pooling re-sequencing uncovers selective loci among goat populations”, 34th ISAG, 2014, Xi'an, China (Oral Presentation)

  “Fine-mapping of a QTL for milk fat percentage on bovine chromosome 5 based on imputed sequencing data”, 33rd ISAG, 2012, Cairns, Australia (Abstract)

  “Polymorphism analysis of genes in a 3.2-Mb region on bovine chromosome 5 associated with milk fat percentage”, 32nd ISAG, 2010, Edinburgh, UK (Abstract)

  7.联系方式

  通讯地址:陕西杨凌西农路22号 西北农林科技大学动物科技学院

  邮编:712100

  Email: xiaolongwang@nwafu.edu.cnxiaolong.wang@vip.163.com

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