Zhao Xin

Xin Zhao, Professor 

College of Animal Science and   Technology

Northwest A&F University
Yangling, Shaanxi 712100 China

Email: zhaoxin@nwsuaf.edu.cn

Education:

1985-1989             Ph.D., Cornell University, Animal Science

                     Minors: Physiology and Nutrition

     

1982-1985             Masters of Science, Nutritional Physiology and Nutritional Biochemistry

                     Nanjing Agricultural University

1978-1982             Bachelor of Science, Animal Science

                     Nanjing Agricultural College

Research Interests:

Research interests include animal nutrition, animal genetics, host (farm animals) - bacterial pathogen interaction.

Awards:

2010                     国家特聘专家

2008                     国家基金委海外及港澳学者合作研究基金

2007-2013             James McGill Professor, McGill University

2006                     Canadian Society of Animal Science's award for Technical Innovation in Enhancing Production of Safe Affordable Food

2002-2006             William Dawson Scholar, McGill University

Publications:
 

Book Chapter

(128).     Ibeagha-Awemu, E.M., P. Kgwatalala and X. Zhao. 2009. Potential for improving health: Calcium bioavailability of milk and dairy products. In: Bioactive components in milk and dairy products, Edited by Young W. Park. Wiley-Blackwell Publishers. p363-378.

(127).     Ibeagha-Awemu, E. M., J. Liu and X. Zhao. 2009. Bioactive components in yogurt products. In: Bioactive components in milk and dairy products. In: Bioactive components in milk and dairy products, Edited by Young W. Park. Wiley-Blackwell Publishers. p235-250.

(126).     Ibeagha, A. E., E. M. Ibeagha-Awemu, J. Mehrzad and X. Zhao. 2007. Selenium, Immune Functions and Health of Dairy Cattle. In: Nutritional Biotechnology in the Feed and Food Industries. Eds by T.P. Lyons, K.A. Jacques and J.M. Hower. 2007. Nottingham University Press., Nottingham, UK.  p289-303.

(125).     Ibeagha-Awemu, E. M. and X. Zhao, 2007. Achievements of research in the field of dairy cattle. Animal production and animal science worldwide - WAAP Book of the Year 2006. Edited by A. Rosati, A. Tewolde and C. Mosconi. Wageningen Academic Publishers. The Netherlands. p115-126.

Review Papers

(124).     Kurtovic I., S. Marshall, X. Zhao and B. Simpson. 2009. Lipases from mammals and fish Marine lipases – properties and potential applications. Rev. Fish Sci. 17:18-40.

(123)      Ibeagha-Awemu, E., P. Kgwatalala and X. Zhao. 2008. A critical analysis of production associated DNA polymorphisms in the genes of cattle, goat, sheep and pig. Mamm. Genome 19:591–617.

(122)      Ibeagha-Awemu, E., P. Kgwatalala, A. Ibeagha and X. Zhao. 2008. A critical analysis of disease associated DNA polymorphisms in the genes of cattle, goat, sheep and pig. Mamm. Genome 19:226-245.

(121).     Zhao X. and P. Lacasse. 2008. Mammary tissue damage during bovine mastitis: causes and control. J. Anim. Sci. (supplement 1) 86:57-65.

(120).     Baurhoo, B., C. Ruiz-Feria, and X. Zhao, 2008. Purified lignin: Nutritional and health impacts on farm animals - A review. Anim. Feed Sci. Technol. 144:175-184.

(119)      Paape, M, D. Bannerman, X. Zhao and J. Lee. 2003. The bovine neutrophil: structure and function in blood and milk. Vet. Res. 34:597-627.

(118).      Capuco, A. V., S. Ellis, S. Hale, E. Long, R. Erdman, X. Zhao, and M. Paape. 2003. Lactation Persistency: Insights from Mammary Cell Proliferation Studies. J. Anim. Sci. 81: (supplement 3) 18-31.

(117).     Paape, M., J. Mehrzad, X. Zhao, J. Detilleux and C. Burvenich 2002. Defense of the bovine mammary gland by polymorphonuclear neutrophil leukocytes. J. Mam. Gland Biol. Neoplasia 7:109-121.

(116).     Jin, L.Z. and X. Zhao. 2000. Intestinal receptors for adhesive fimbriae of enterotoxigenic Escherichia coli (ETEC) K88 in swine –A review. Appl. Microbiol.Biotechnol. 54: 311-318.

Publications in Refereed Journals:

(115).      Ibeagha-Awemu, E., A. Ibeagha, S. Messier and X. Zhao. 2010. Proteomics, genomics and pathway analyses of E. coli and S. aureus infected milk whey reveal molecular pathways and networks involved in mastitis. J. Proteome Res. (accepted) DOI: 10.1021/pr100336e

(114).     Yu, C., Z-R Shi, C-Y Chu, K-H Lee, X. Zhao and J-W Lee. 2010. Expression of bovine granulocyte chemotactic protein-2 (GCP-2) in neutrophils and a mammary epithelial cell line (MAC-T) in response to various bacterial cell wall components. Vet J. DOI:10.1016/j.tvjl.2009.07.012

(113).     Kurtovic I., S. Marshall, X. Zhao and B. Simpson. 2010. Purification and properties of digestive lipases from Chinook salmon (Oncorhynchus tshawytscha) and New Zealand hoki (Macruronus novaezelandiae). Fish Physiol. Biochem. DOI:10.1007/s10695-010-9382-y.

(112).     Zhu, L., X. Ding, J. Tao, J. Wang,  X. Zhao, and G. Zhu. 2010. Critical role of cholesterol in bovine herpesvirus type 1 infection of MDBK cells. Vet. Microbiol. 144:51-57.

(111).     Said, K. B, J. Ismail, J. Campbell, M.R. Mulvey, A. Bourgault, S. Mercier and X. Zhao. 2010. Regional profiling for genotype diversity of mastitis-specific Staphylococcus aureus lineage in Canada using clumping factor A, pulsed field gel electrophoresis, and spa-typing. J. Clin Microbiol. 48:375-386.

(110).      Martinez-Diaz, M.A., L. Che, M. Albornoz, M.M. Seneda, D. Collis, A. R.S. Coutinho, N. El-Beirouthi, D. Laurin, X. Zhao and V. Bordignon. 2010. Pre- and Post-Implantation Development of Swine Cloned Embryos Derived from Fibroblasts and Bone Marrow Cells after Inhibition of Histone Deacetylases. Cloning Stem Cells 12:85-94.

(109).     Said, K. B., G. Zhu and X. Zhao. 2010. Organ and host-specific clonal groups of Staphylococcus aureus from human infections and bovine mastitis revealed by the clumping factor A gene. Foodborne Path. Dis. 7:111-119.

(108).     Zhu, L.Q., M. Ren, Y.Q. Lin, X.Y. Ding, G.P. Zhang, X. Zhao and G.Q. Zhu. 2009. Identification of a bovine viral diarrhea virus 2 isolated from cattle in China. Acta Virologica 53: 131 – 134.

 (107).    Baurhoo, B., P. R. Ferket and X. Zhao, 2009. Effects of diets containing different concentrations of mannanoligosaccharide or antibiotics on growth performance, intestinal development, cecal and litter microbial populations, and carcass parameters of broilers. Poultry Sci. 88 :2262–2272.

(106).      Kgwatalala, P.M., E. M. Ibeagha-Awemu, A. Mustafa and X. Zhao. 2009. Stearoyl-CoA Desaturase 1 Genotype and Stage of Lactation Influence Milk Fatty Acid Composition of Canadian Holstein Cows. Animal Genet. 40, 609–615.

(105).     Lai, I.H., J. H. Tsao, Y. P. Lu, J.W. Lee, X. Zhao, F. L. Chien and S. J.T. Mao. 2009. Neutrophils as one of the major haptoglobin sources in mastitis affected milk. Vet. Res. 40:17.

 (104).    Loiselle, M.C., C. Ster, B. Talbot, X. Zhao, G. Wagner, Y. Boisclair and P. Lacasse. 2009. Impact of postpartum milking frequency on the immune system and the blood metabolite concentration of dairy cows. J. Dairy Sci. 92:1900–1912.

(103).     Said, K. B., K. Ramotar, G. Zhu and X. Zhao. 2009. Repeat-based subtyping and evolutionary analysis of Staphylococcus aureus of human and bovine mastitis lineage using the R domain of the clumping factor A gene. Diagn. Microbiol. Infect Dis. 63:24–37.

(102).     Baurhoo, B., F. Goldflus and X. Zhao. 2009. Purified cell wall of Saccharomyces cerevisiae increases protection against intestinal pathogens in broiler chickens. International J. Poultry Sci. 8: 133-137.

(101).     Ibeagha, A. E., E. Ibeagha-Awemu, J. Mehrzad, B. Baurhoo, P. Kgwatalala and X. Zhao. 2009. The effect of selenium source and supplementation on neutrophil functions in dairy cows. Animal 3:1037–1043.

(100).     Kgwatalala, P. M., E. Ibeagha-Awemu, J. Hayes and X. Zhao. 2009. Stearoyl-CoA desaturase 1 (SCD1) 3´UTR SNPs and their influence on milk fatty acid composition of Canadian Holstein cows. J. Anim. Breed. Genet. 126:394–403.

(99).      Kgwatalala, P. M., E. Ibeagha-Awemu, A. Mustafa and X. Zhao. 2009. Influence of stearoyl-CoA desaturase 1 (SCD1) genotype and stage of lactation on desaturase indices and fatty acid composition of Canadian Jersey cows. J. Dairy Sci. 92:1220–1228.

(98).       Tiwari, J., S. Barrington and X. Zhao. 2009. Effect on manure characteristics of supplementing grower hog ration with clinoptilolite. Micropor. Mesopor. Mater. 118:93-99.

(97).       Ibeagha-Awemu, E. M., J. Lee, A. Ibeagha and X. Zhao. 2008. Bovine CD14 gene characterization and relationship between polymorphisms and surface expression on monocytes and polymorphonuclear neutrophils. BMC genetics 9:50.

(96).       [My paper]Liu, J. R., C. Duan, X. Zhao, J. Tzen, K. Cheng, and C. Pai. 2008. Cloning of a rumen fungal xylanase gene and purification of the recombinant enzyme via artificial oil bodies. Appl Microbiol Biotechnol. 79:225-233.

(95).       Mehrzad, J. and X. Zhao. 2008. T lymphocyte proliferative capacity and CD4+/CD8+ ratio in primiparous and pluriparous lactating cows.  J. Dairy Res. 75:457-465.

(94).       Baldassarre, H., D. Hockley, B. Olaniyan, E. Brochu, X. Zhao, A. Mustafa and V. Bordignon. 2008. Milk composition studies in transgenic goats expressing recombinant human butyryl-cholinesterase in the mammary gland. Transgenic Res. 17: 863-872.

(93).       Cao, W., S. Tang, H. Yuan, H. Wang, Y. Li, X. Zhao and H. Lu. 2008. A Mycobacterium tuberculosis antigen Wag31 induces expression of a C-chemokine, XCL2, in macrophages. Current Microbiol. 57:189-194.

(92).       Cao, W., N. Liu, S. Tang, L. Bao, L. Shen, H. Yuan, Y. Li, X. Zhao and H. Lu. 2008. Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines. BBA-Gen. Subjects. 1780:873-880.

(91).      Jung, S. J., R. Houde, B. Baurhoo, X. Zhao and B. Lee. 2008. Effects of galacto-oligosaccharides and a Bifidobacteria lactis - based probiotic strain on the growth performance and fecal microflora of broiler chickens. Poultry Sci. 87:1694–1699.

(90).       Baldassarre, H., D. Hockley, M. Doré, E. Brochu, B. Hakier, X. Zhao and V. Bordignon. 2008. Lactation performance of transgenic goats expressing recombinant human butyryl-cholinesterase in the milk. Transgenic Res. 17:73-84.

(89).       Abdukakova, S., X. Zhao and C. Ruiz-Feria. 2008. Arginine and vitamin E modulate the subpopulations of T-lymphocytes in broiler chickens. Poultry Sci. 87:50-55.

(88).      Ibeagha-Awemu, E. M., J. Lee, A. Ibeagha, D. Bannerman, M. Paape and X. Zhao. 2008. Bacterial lipopolysaccharide induces increased expression of toll-like receptor (TLR) 4 and downstream TLR signalling molecules in bovine mammary epithelial cells. Vet Res. 39:11 (12 pages).

(87).      Wang, J., N. Liu, Z. Liu, Y. Li, C. Song, H. Yuan, Y. Li, X. Zhao and H. Lu. 2008. The orphan nuclear receptor RVR recruits Tip60 and HDAC1 to regulate Apolipoprotein CIII promoter. BBA – Mol. Cell Res. 1783:224-236.

(86) Liu, J., B. Yu, X. Zhao and K. Cheng. 2007. Coexpression of rumen microbial ß-glucanase and xylanase genes in Lactobacillus reuteri. Appl. Microbiol. Biotechnol. 77:117-124.

(85) Wang, J., Y. Li, M. Zhang, Z. Liu, C. Wu, J. Liu, H. Yuan, Y. Li, X. Zhao and H. Lu. 2007. A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor RVR and removes RVR-induced inhibition of apoCIII transcription. FEBS Journal. 274:5370-5381.

(84).      Baurhoo, B., A. Letellier, X. Zhao and C. Ruiz-Feria. 2007. cecal populations of Lactobacilli and Bifidobacteria and E. coli populations after E. coli in vivo challenge in birds fed diets with purified lignin or mannanoligosaccharides. Poultry Sci. 86:2509-2516.

(83) Ibeagha-Awemu, E. M., E. Prinzenberg, O. Jann, G. Lühken, A. Ibeagha, X. Zhao and G. Erhardt. 2007.       Molecular characterization of bovine CSN1S2B and extensive distribution of Zebu specific milk protein alleles in European cattle. J. Dairy Sci. 90:3522–3529.

(82) Leung, S., S. Barrington, Y. Wan, X. Zhao and B. El-Husseini. 2007. Zeolite (clinoptilolite) as feed additive to reduce manure mineral content.  Bioresource Technol 98:3309-3316.

(81).       Kgwatalala, P. M., E. Ibeagha-Awemu, J. Hayes and X. Zhao. 2007. Single nucleotide polymorphisms in the open reading frame of the stearoyl- CoA desaturase gene and resulting genetic variants in Canadian Holstein and Jersey cows. DNA Seq. 18:357-362.

(80).      Boulanger, V., X. Zhao, K. Lauzon, A. Bouetard and P. Lacasse. 2007. Effects of nitric oxide on bovine polymorphonuclear functions. Can. J. Vet Res. 71:52-58.

(79).       Zhang, R., A. Mustafa, and X. Zhao. 2007. Effects of feeding oilseeds on nutrient utilization by lactating ewes. Small Rumin. Res. 67:307-311.

(78).      Zuta, P. C., B. Simpson, X. Zhao and L. Leclerc.  2007. The effect of α-tocopherol on the oxidation of mackerel oil. Food Chemistry 100:800-807.

(77).       Zhang, R.H., A. Mustafa, and X. Zhao. 2006. Blood metabolites and fatty acid composition of milk and cheese from ewes fed oilseeds. Can. J. Anim. Sci. 86: 547–556.

(76) Lee, J. and X. Zhao. 2006. The effect of recombinant human interleukin-13and interleukin-8 on bovine neutrophil degranulation. J. Internal. Cooperation 1:9-24.

(75) Leung, S., S. Barrington, X. Zhao and B. El-Husseini. 2006. Effect of particle size on physio-chemical properties of clinoptilolite as feed additive. Micropor. Mesopor. Mater. 95:48-56.

(74).       Zhang, R., A. Mustafa, K. Ng-Kwai-Hang and X. Zhao. 2006.  Effects of freezing on composition and fatty acid profiles of sheep milk and cheese.  Small Rumin. Res. 64:203-210.

(73).      Lauzon, K., X. Zhao and P. Lacasse. 2006. Deferoxamine prevents tissue damage during endotoxin-induced mastitis in dairy cows. J. Dairy Sci. 89:3846–3857.

(72).       Zhang, R., A. Mustafa and Zhao, X. 2006. Effects of flaxseed supplementation to lactating ewes on milk composition, cheese yield and fatty acid composition of milk and cheese.  Small Rumin. Res. 63:233-241.

(71).       Lee, J., D. Bannerman, M. Paape, M. Huang and X. Zhao. 2006. Characterization of cytokine expression in milk somatic cells during intramammary infections with Escherichia coli or Staphylococcus aureus by real-time PCR. Vet. Res. 37:219-229.

(70).       Zhang, R., A. Mustafa and X. Zhao. 2006. Effects of feeding oilseeds rich in linoleic and linolenic fatty acids to lactating ewes on cheese yield and on fatty acid composition of milk and cheese. Anim. Feed Sci. Technol. 127:220-233.

(69).       Lauzon, K., X. Zhao, A. Bouetard, L. Delbecchi, B. Paquette and P. Lacasse. 2005. Antioxidants to prevent bovine neutrophil-induced mammary epithelial cell damage. J. Dairy Sci. 88:4295-4303.

(68).       Liu, R., B. Yu, F. Liu, K. Cheng and X. Zhao. 2005. Expression of rumen microbial fibrolytic enzyme genes in probiotic lactobacillus reuteri. Appl. Environ. Microbiol. 71:6769-6775.

(67).       Gokavi, S., L. Zhang, M. Huang, X. Zhao and M. Guo, 2005.  Oats based symbiotic beverage containing L. plantarum, L paracasei and L. acidophilus.  J. Food Sci. 70:M216-M223.

(66).       Lee, J. W., C. O’Brien, A. Guidry, M. Paape, K. Shafer-Weaver, and X. Zhao. 2005. The effect of a trivalent vaccine against Staphylococcus aureus mastitis on lymphocyte subpopulations, antibody production and neutrophil phagocytosis. Can. J. Vet. Res. 69:11-18.

(65).       Tian, S. Z., C. Chang, M. Hsu, H. Peh, M. Huang; J. Lee and X. Zhao. 2005. Comparison of morphology, viability and functions between blood and milk neutrophils from peak lactating goats. Can. J. Vet. Res. 69:39-45.

 (64)      Li, Y., Z. Yu, X. Zhao and S. Shen. 2005.  Identification and Characterization of Hepsin/-TM, a Non-transmembrane Hepsin Isoform. BBA - Gene Structure and Expression. 1681:157-165.

(63)       Mehrzad, J., C. Desrosiers, K. Lauzon, G. Robitaille, X. Zhao and P. Lacasse. 2005. Proteases involved in mammary tissue damage during endotoxin-induced mastitis in dairy cows. J. Dairy Sci. 88:211-222.

(62) Hidiroglou, N., S. Gilani, E. Long, X. Zhao, K. Cockell and R. Peace. 2004. The influence of dietary vitamin E, fat and methionine on blood cholesterol, homocysteine levels and on oxidation of low density lipoprotein in gerbils. J. Nutri. Biochem. 15:730-740.

Bannerman, D. D., M. Paape, J. Lee, X. Zhao, J. Hope, and P. Rainard. 2004. Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection. Clin. Diagn. Lab. Immunol. 11:463-472.

(60) Huang, M. K., Y. Choi, R. Houde, J. Lee, B. Lee, and X. Zhao. 2004.  Effects of Lactobacilli and an Acidophilic Fungus on the Production Performance and Immune Responses in Broiler Chickens. Poultry Sci. 83:788-795.

(59)       Gong, Y. and X. Zhao. 2003. Shc-dependent pathway is redundant but dominant in MAPK cascade activation by EGF receptors: a modeling inference. FEBS let. 554:467-472.

(58) Xu, Y., D. Mousseau, D. Banville, X. Zhao and S. Shen. 2003.  SHP-1 sensitizes MCF-7 cells to trichostatin A-induced apoptosis by modulating PI3K-dependent events. Cell Death Differ. 12: 1213-1214.

(57).       Lee, J. W., M. Paape, T. Elsasser, and X. Zhao. 2003. Recombinant soluble CD14 reduces severity of intramammary infection by Escherichia coli. Infect. Immun. 71:4034-4039.

(56).       Lee, J. W., M. Paape, T. Elsasser, and X. Zhao. 2003. Elevated milk soluble CD14 in bovine mammary glands challenged with Escherichia coli lipopolysaccharide.  J. Dairy Sci. 86: 2382-2389.

(55) Lee, J. W., X. Zhao and M. Paape. 2003. Recombinant bovine soluble CD14 reduces severity of experimental Escherichia coli mastitis in mice. Vet. Res. 34:307-316.

(54). Lu, C. H., C. Chang, P. Lee, C. Wu and X. Zhao, 2003. Functional characterization of mammary gland of Holstein cow under humid tropical summer climates. Asian-Aust. J. Anim. Sci. 16:988-995.

(53). Luimes, P. H., J. Cant, X. Zhao and D. Petitclerc. 2002. Delineating potential control mechanisms of mammary protein synthesis utilizing atropine. J. Dairy Sci. 85:1445‑1453

(52). Boulanger, V., X. Zhao and P. Lacasse. 2002. Protective effect of melatonin and catalase in bovine neutrophil-induced model of mammary cell damage. J. Dairy Sci. 85:562‑569.

(51). Su, W. J., C. Chang, H. Peh, S. Lee, M. Huang and X. Zhao.  2002. Apoptosis of infiltrated neutrophils during mammary involution in goat occurs in association with oxidative stress. Am. J. Vet. Res. 63:241‑246.

                    

(50).       Long, E., A. Capuco and X. Zhao. 2001. Cloning of bovine eukaryotic translation initiation factor 4E (eIF‑4E) and its expression in the bovine mammary gland at different physiological stages. DNA Seq.12:319‑329.                                               

(49) Boulanger, V., L. Bouchard, X. Zhao and P. Lacasse. 2001. Induction of nitric oxide production by bovine mammary epithelial cells and blood leukocytes. J. Dairy Sci. 84:1430-1437.

(48). Long, E., A. Capuco, D. Wood, T. Sonstegard, G. Tomita, M. Paape and X. Zhao. 2001. Escherichia coli induces apoptosis and proliferation of mammary cells. Cell Death Differ. 8: 808-816.

(47) Long, E., A. Lazaris-Karatzus, C. Karatzas and X. Zhao.  2001. The effect of overexpressing eukaryotic translation initiation factor 4E (eIE-4E) on the proliferation of a bovine mammary epithelial cell line. Int. J. Biochem. Cell Biol. 33:133-141.

(46). Xu, Y., D. Banville, H. Zhao, X. Zhao and S. Shen. 2001. NF-Y factor binding to two CCAAT-elements in P1 promoter of the SHP-1 gene interplays as tissue-specifically transcriptional positive and negative regulator assembled in the nucleoprotein complexes. Gene 269:141-153.

(45) Xiao, C., L. Jin and X. Zhao. 2001. Bovine casein peptides co-stimulate naive macrophages with lipopolysaccharide for proinflammatory cytokine production and nitric oxide release. J. Sci. Food Agri. 81:300-304.

(44) Boudjellab, N., H. Chan-Tang and X. Zhao. 2000. Bovine interleukin-1 expression by cultured mammary epithelial cells (MAC-T) and its involvement in the release of MAC-T derived interleukin-8. Comp. Physiol. Biochem. 127:191-199.

(43) Jin, L. Z., R. Marquardt and X. Zhao. 2000. A strain of Enterococcus faecium inhibited the adhesion of enterotoxigenic Escherichia coli K88 to porcine small intestinal mucus receptors. Appl. Environ. Microbiol. 66:4200-4204.

(42) Lee, J. and X. Zhao. 2000. Recombinant human interleukin-8, but not human interleukin-1, induces bovine neutrophil migration in an in vitro co-culture system. Cell Biology International. 24:889-895.

(41) Kubow, S., T. Woodward, J. Turner, A. Nicodemo, E. Long and X. Zhao. 2000. Lipid peroxidation is associated with the inhibitory action of all-trans retinoic acid on mammary cell transformation. Anticancer Res. 20: 843-848.

(40) Li, X., N. Boudjellab and X. Zhao. 2000. Combined PCR and slot blot assay for detection of salmonella and listeria monocytogenes. Int. J. Food Microbiol.   56:167-177.

(39) Bouchard, L., S. Blais, C. Beaudry, X. Zhao and P. Lacasse.  1999. Nitric oxide production during endotoxin-induced mastitis in the cow. J. Dairy Sci. 82:2574-2581.

(38) Boudjellab, N., J. Grosclaude, X. Zhao and J. Collin.1999. Monoclonal antibodies as probes for the evolution of antigenicity of bovine and porcine aspartyl proteinases according to pH. J. Agric. Food Chem. 47:3991-3995.

(37) Li. X., X. Zhao and S. Ma. 1999. Secretion of 92 kDa gelatinase (MMP-9) by bovine neutrophils. Vet. Immuno. Immunopathol. 67:247-258.

(36) Allard, B., E. Long, E. Block and X. Zhao. 1999. Dependence of superoxide anion production on extracellular and intracellular calcium ions and protein kinase C in PMA-stimulated bovine neutrophils. Can. J. Vet. Res. 63:13-17.

(35) Hidiroglou, M., X. Zhao, S. Raffy and P. Toutain. 1999. Pharmacokinetics study of calcium 45Ca administratered intravenously following intramuscular injection of vitamin D3 or 25 hydroxy vitamin D3 in the ewe-lamb. Comp. Physiol. Biochem. 122:277-282.

(34) Boudjellab, N., J. Grosclaude, X. Zhao and J. Collin. 1998. Development of an inhibition enzyme-linked immunosorbent assay for the detection of residual swine pepsin in a soft cheese sample. J. Agric. Food Chem. 46:4030-4033.

(33) Long, E., H. Huynh and X. Zhao. 1998. Involvement of insulin-like growth factor-I and its binding proteins in proliferation and differentiation of murine bone marrow-derived macrophage precursors. Endocrine 9:185-192.

(32). Boudjellab, N., H. Chan-Tang, X. Li and X. Zhao. 1998. Bovine mammary epithelial cells secrete interleukin-8 in response to lipopolysaccharide stimulation. Am. J. Vet. Res. 59:1563-1567.

(31).       Simpson, M. V., M. Hidiroglou, T. Batra and X. Zhao. 1998.  Reduced level of creatine kinase in the plasma of Holstein cows supplemented with d-a-tocopherol acetate. Can. J. Anim. Sci. 78:147-149.

(30) Hidiroglou, M., T. Batra and X. Zhao.  1997. Comparison of bioavailability after multiple or single oral dosing of different formulations of vitamin C in sheep. Reprod. Nutr. Dev. 37:443-448.

(29) Hidiroglou, M., T. Batra and X. Zhao.  1997. Bioavailability of vitamin E compounds and the effect of supplementation on release of superoxide and hydrogen peroxide by bovine neutrophils. J. Dairy Sci. 80:187-193.

(28) Woodward, T. L., J. Turner, H. Hung and X. Zhao.  1996. Inhibition of cellular proliferation and modulation of insulin-like growth factor binding proteins by retinoids in a bovine mammary epithelial cell line. J. Cell. Physiol. 167:488-499.

(27) Hidiroglou, M., G. Butler and X. Zhao. 1996. Distribution of radiovitamin A administered to sheep by four routes. J. Anim. Physiol. Anim. Nutri. 75:142-155.

(26) Lin, Y., J. Cai, J. Turner and X. Zhao. 1996. Quantification of bovine neutrophil diapedesis across bovine mammary epithelia in vitro. Can. J. Vet. Res. 60:145-149.

(25) Lin, Y., L. Xia, J. Turner and X. Zhao. 1995. Morphological observation of neutrophil diapedesis across bovine mammary gland epithelium in vitro. Am. J. Vet. Res. 56:203-207.

(24) Scollan, N. D., X. Zhao, J. Brisbane, N. Jessop, G. Allen, J. Oldham and B. McBride. 1994. Characterization of Na+, K+-ATPase in erythrocytes of dairy cows: effect of diet and genetic selection for milk solids. Can. J. Anim. Sci. 74:641-648.

(23) Zhao, X., B. McBride, L. Trouten-Radford, L. Golfman and J. Burton. 1994. Somatotropin and Insulin-like growth factor-I concentrations in plasma and milk after daily or sustained-release exogenous somatotropin administrations. Dom. Anim. Endocrinol. 11:209-216.

(22) Zhao, X., B. McBride, L. Trouten-Radford and J. Burton. 1993. Effects of insulin-like growth factor-I and its analogs on bovine hydrogen peroxide release by neutrophils and blastogenesis by mononuclear cells. J. Endocrinol. 139:259-265.

(21). Zhao, X., B. McBride, L. Trouten-Radford and K. Lissemore. 1993. Decreased insulin-like growth factor-I receptor sites on circulating mononuclear cells from cows with persistent lymphocytosis. J. Recept. Res. 13:1161-1172.

(20) Kuehner, L., D. Rieger, J. Walton, X. Zhao and W. Johnson. 1993. The effect of a single depot injection of recombinant bovine somatotropin on follicular development and embryo yield in superovulated Holstein heifers. Theriogenol. 40:1003-1013.

(19) Zhao, X., J. Burton and B. McBride. 1992. Lactation, Reproductive and health responses of dairy cows receiving somatotropin via daily injections or a sustained-release formulation. J. Dairy Sci. 75:3122-3130.

(18) Zhao, X., B. McBride, I. Politis, H. Hung, R. Akers, J. Burton and J. Turner,. 1992. Receptor binding and growth-promoting activity of insulin-like growth factor-I in a bovine mammary epithelial cell line (MAC-T3).  J. Endocrinol. 134:307-312.

(17) Politis, I., X. Zhao, B. McBride, and J. Burton. 1992. Comparison of several functional properties between milk macrophages and blood monocytes. Anim. Sci. Rev. 14:83-96.

(16) Zhao, X., B. McBride, L. Trouten-Radford and J. Burton. 1992. Presence of specific insulin-like growth factor-I receptors on bovine mononuclear cells. J. Recept. Res. 12:117-129.

(15) Gibson, J. P., B. McBride, J. Burton, I. Politis and X. Zhao. 1992. Effect on production traits of the use of recombinant bovine somatotropin for up to three consecutive lactations. J. Dairy Sci. 75:837-846.

(14) Politis, I., X. Zhao, B. McBride, and J. Burton. 1992. Function of bovine mammary macrophages as antigen presenting cells.  Vet. Immunol. Immunopath. 30:399-410.

(13) Zhao, X. and R. Gorewit. 1991. Characterization of vasopressin binding sites in bovine mammary tissue.  Neuropeptides (Life Science Advances) 10:1-8.

(12) Zhao, X., P. Groenewegen, B. McBride, J. Burton and T. Elsasser. 1991. Radioimmunoassay for bovine IGF-I in bovine milk.  Can. J. Anim. Sci. 71:669-674. 

(11) Politis, I., X. Zhao, B. McBride, and J. Burton. 1991. Examination of the chemotactic properties of bovine mammary macrophages. Can. J. Vet. Res. 55:321-324.

(10) Politis, I., B. McBride, J. Burton, X. Zhao, and J. Turner. 1991. Plasminogen activator production by bovine milk macrophages and blood monocytes. Am. J. Vet. Res. 52:1208-1213.

(9)   Politis, I., X. Zhao, B. McBride, and J. Burton. 1991. Effect of bovine skim milk and whey on monocyte function. J. Dairy Sci. 74:2467-2471.

(8)   Politis, I., X. Zhao, B. McBride, and J. Burton. 1991. The effect of lipopolysaccharide on bovine macrophage function.  Can. J. Vet. Res. 55:220-223.

(7)   Politis, I., B. McBride, J. Burton, X. Zhao, and J. Turner.  1991. Secretion of interleukin 1 by bovine mammary gland macrophages. Am. J. Vet. Res. 52:858-862.

(6)   Trouten-Radford, L. M., X. Zhao, and B. McBride.  1991.  IGF-I receptors in embryonic skeletal muscle of three strains of chickens selected for differences in growth capacity.  Dom. Anim. Endocrinol. 8:129-137

(5)   Zhao, X., R. Gorewit and W. Currie. 1990. Effects of N-acetylimidazole on oxytocin receptors in bovine mammary tissue. J. Recept. Res. 10:287-298

(4)   Gorewit, R. C., D. Aneshansley, D. Ludington, R. Pellerin and X. Zhao.  1989.  AC voltages on water bowls: Effects on lactating Holsteins.  J. Dairy Sci. 72:2184-2192

(3)   Zhao, X. and R. Gorewit. 1987. Inositol-phosphate response to oxytocin stimulation in dispersed bovine mammary cells.  Neuropeptides 10:227-233.

(2).  Zhao, X. and R. Gorewit. 1987.  Oxytocin receptors in bovine mammary tissue.  J. Recept. Res. 7:729-741.

(1).  Zhao, X. and H. Zhengkang.  1986.  Effect of volatile fatty acids infused intraruminally and added to ration on the ruminal metabolism and voluntary feed intake of goats.  J. Nanjing Agric. Univ.  No. 1 P. 74-83.

Abstracts and Conference Presentations