Wang Gaoxue

Gender: Male

Date of Birth: September, 1965. 

Department of aquatic Science, College of Animal Sciences;

Northwest A&F University, Yangling, Shaanxi Province, 712100

Telephone: +86 87092139

Email: wanggaoxue@126.com

Education:

B.S. Shaanxi Normal University, College of Life Science 1986

Ph.D. Northwest A&F University, College of Animal Science 2006

Post Doctoral Research, University of Animal Science Department of Aquatic Science

Research interests:

(1) Innovation and development of bio-medicine for aquatic organisms

A primary research focus is screening effective natural product from plant and microorganism, which could kill bacteria, parasite and harmful algae and promote breeding animal’s immune system and growth, aiming to develop bio-medicines with no side effects and feed additive while discover novel active molecular and study structure-activity relationship to biomimetic synthesis or synthesis raw materials for bio-medicines and feed additive. Develop bio-medicines and feed addictive with independent intellectual property right.

(2) Molecular etiology and biological product research

    Mainly focus on pathogenesis of the main pathogen in breeding aquatic animals; fundamental research and clinical application of low virulent or gene-engineering vaccine; isolation and screen of beneficial microorganism from intestine of aquatic animals and study the relationship between various flora, so as to develop microbial preparation and modifier for aquaculture.   

Teaching:

Disease of Aquatic Animals (for undergraduate students)

Advanced hydrobiology and Experimental Technique

Research Method and Experimental Technique of Aquatic Animals’ Disease

Research Subject of Advanced Hydrobiology

Project:

  In charge of more than 10 research projects in recent years including: two key projects from Shaanxi Province; one sub-project of a non-profit project from the Ministry of Agriculture; One scientific project from Changzhou city in Jiangsu province; One special project funded by Northwest A&F University; four projects funded by companies.

Awards:

Year          Tile of Award         Title of Project                   Awarding Agency

2001

Third-class prize of Shannxi Provincial Scientific and Technological Advances Awardcertificate No.2000-893

Breeding technique and its application on rainbow trout in northern Shannxi province

1

Government of Shannxi  Province

2000

First-class prize of Yanan cities’ Scientific and Technological Advances Award

County-yard economy-economical animal breeding

1

Government of Yanan city

2000

Second-class prize of Yanan cities’ Scientific and Technological Advances Award

Breeding technique and its application on rainbow trout in northern Shannxi province

2

Government of Yanan city

2007

Second-class excellent papers

Influence of Polysaccharide from Grey polypore on the immune function of crucian carp

1

Fisheries Society of Liaoning Province

Patent:

Title

Patent NO.

Ranking

Concentrated and leafing water quality modifier of micro-ecology balance

ZL200510041775.4Authorized

1

Plant-derived osthole as antiparasitic agent for aquatic animals

Application of a novel microorganism and its genetic sequence

Nicotine and Brucea javanica as novel antiparasitic agent for aquatic animals

A non-polluted fishery medicine from plant

Lipid solubility components from Periplocasepium as non-polluted fishery medicine and method for preparation

Exopleura of Ginkgo biloba L as antiparasitic for aquatic animals

Preparation method of veterinary injections containing calcium, phosphor, magnesium, or calcium and phosphor

Application of sanguinarine on the preparation of aquatic medicines and preparation method as formulation

ZL200510041733.0Authorized

ZL200610105262.XAuthorized

ZL02139390.7Authorized

1

1

2

ZL200510096018.7Authorized

ZL200510096019.1Authorized

ZL200310118938.5Authorized

2

3

1

ZL200310118939.XAuthorized

1

ZL 200710017213.5

1

Application of C22H34O3 in fishery medicine and  its preparation method

ZL200710017212.0Authorized

1

Application of C20H27O3 in fishery medicine and  its preparation method

ZL 200710017214.X

1

A cyclic decapeptide from microorganism metabolin used for feed addictive and its application

Application of gracillin in the medicine of killing external parasite in aquatic animals

Application of aglicone from great burdock achene in the medicine of killing external parasite in aquatic animals

Application of  isopimpinellin in fishery medicine and its preparation method

Application of extract of leaf of longstalck peach

200810150946.0Accepted

200810231792.8Accepted

20081023791.3Accepted

200810024734.8

200910021257.4

1

1

1

2

2

Publications:

Gao-xue Wang, Zhuang Zhou, Chao Cheng, Jiayun Yao, Zhengwei Yang. 2008. Osthol and Isopimpinellin from Fructus Cnidii to Control Dactylogyrus intermedius in Carassius auratus. Veterinary Parasitology. 158 (1-2): 144-151.

Gao-xue Wang, Dong-xin Jiang, Zhuang Zhou, Yun- Kui Zhao, Ye- Hua Shen. 2009. In vivo assessment of anthelmintic efficacy of ginkgolic acids (C13:0, C15:1) on removal of Pseudodactylogyrus in European eel. Aquaculture. 297:38–43.

Gao-xue Wang, Jing Han, Ting-ting Feng, Fu-yuan Li, Bin Zhu. 2009. Bio-assay guided isolation and identification of active compounds from Fructus Arctii against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus). Parasitology Research. 106:247-255.

Gao-xue Wang, Yan Li, Xiao-lin Liu, Yong-hua Wang. 2009. Understanding the Aquatic Toxicity of Pesticide: Structure-Activity Relationship and Molecular Descriptors to Distinguish the Ratings of Toxicity. QSAR & Combinatorial Science. 28 (11-12): 1418-1431.

You-Tao Liu, Fan Wang, Gao-Xue Wang, Jing Han, Yong Wang, Yong-Hua Wang. 2010. In vivo anthelmintic activity of crude extracts of Radix angelicae pubescentis, Fructus bruceae, Caulis spatholobi, Semen aesculi, and Semen pharbitidis against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus). Parasitology Research.106:1233-1239.

Gao-xue Wang, Zhuang Zhou , Dong-xin Jiang , Jing Han, Jian-Fu Wang, Liang-Wei Zhao, Jun Li. 2010. In vivo anthelmintic activity of five alkaloids from Macleaya microcarpa (Maxim) Fedde against Dactylogyrus intermedius in Carassius auratus. Veterinary Parasitology. http://dx.doi.org/10.1016/j.vetpar.2010.03.032. Accepted.

G.-X Wang, J Han, L-W Zhao, D-X Jiang, Y-T Liu, X-L Liu. 2010. Anthelmintic activity of steroidal saponins from Pairs polyphylla. Phytomedicine. 10.1016/j.phymed.2010.04.012. Accept.

Gao-xue Wang, You-Tao Liu, Fu-Yuan Li, Hong-Tao Gao, Yi Lei, Xiao-Lin Liu. 2010. Immunostimulatory activities of Bacillus simplex DR-834 to carp (Cyprinus carpio). Fish & Shellfish Immunology. http://dx.doi.org/10.1016/j.fsi.2010.03.014. Accept.

WANG Gao-xueLI JunZHAO Liang-weiZHOU ZhuangSHEN Ye-huaTIAN Wei-hua. 2009. Ethanol extract of plant Dioscorea zingiberensis against dactylogyrid Dactylogyrus intermedius found in goldfish Carassius auratus. Journal of Dalian Fisheries University. 24(5): 393-399.

WANG Gao-xue ZHAO Liang-wei LI Jun. 2009. Antiparasitic Efficacy of 17 Plant Extracts Against Dactylogyrus. Progress in Veterinary Medicine. 30(6): 21-24.

WANG Gao-xueMA Qiu-liCHENG ChaoZHAO Yun-kuiXU YuSHEN Ye-huaYUAN Ming . 2008 Study on active site of 8 plants to control the Dactylogyrus of fish. Journal of Northwest A & F University(Natural Science Edition). 36 (3) : 64-6874.

WANG Gao-xueWANG Jian-fuYUAN Ju-linSHEN Ye-huaZHENG WeiLI Li. 2007. Activity of Sanguinarine from Macleaya cordata to Dactylogyrus and Six Pathogenic Bacteria in Aquaculture. Acta Botanica Boreali-Occidentalia Sinica. 27(8): 1650-1655.

WANG Gao-xueZHAO Yun-kuiYAO Jia-yunSHEN Ye-huaZHENG WeiWANG Jian-hua. 2006. Study on killing activity of ginkgolic acids to pathogen and dactylogyrus of fish. Journal of Northwest Sci-tech University of Agriculture and Forestry. 34(10): 11-15.

WANG Gao-xue,CHENG Chao CHEN An-liang SHEN Ye-hua ZHANG Xing.  2006. Dactylogyrus Killing Efficacies of 22 Plants Extracts and Its 6 Compounds. Acta Botanica Boreali-Occidentalia Sinica. 26(12): 2567-2573.

WANG Gao-xueXU YuWANG Jian-huaSHEN Ye-hua. 2006. Study on the Killing of the 29 Species of Plants Extraction to the Dactylogyrus. Freshwater Fisheries. 36(3): 3-8.

WANG Gao-xue ,HUANG Zeng-rong. 2006. Studies on the pathogen and histopathology of septicemia in Esox lucius. Journal of Fisheries of China. 30(3): 383-389.

WANG Gao-xue, FU Wei-fa CUI Jing YUAN Ming YAO Lu . 2009. Effects of active components from Bacillus mycoides metabolite on immune functions of mice. Microbiology. 36(6): 858-864.

WANG Gao-xue ,DUAN Xing ,YUAN Ju-lin ,GU Zhong-qi, GAO Hong-tao. 2008. Identification, fermental optimization and exploratory development of an actinomycete strain against diverse aquatic zymad. Journal of Shanghai Fisheries University. 17(5): 591-597.

YUAN Ju-lin, WANG Gao-xue, WANG Jian-fu ,LIANG Chao-jun, GU Zhong-qi ,CUI Jing ,YUAN Ming.  2008. Studies on Marine Streptomyces FA-F-5's inhibitory reaction to the Aquatic Pathogens. Journal of Northwest A & F University. 36(1): 79-85.

WANG Gao-xueCUI JingFU Wei-faBAI BingYUAN MingLAI Hang-xian. 2007. Investigations into the Metabolite's Active Fraction of Four Bacteria on Enhancing Carassius auratus Immunological Function. Freshwater Fisheries. 37(1):12-18.

WANG Gao-xue ,FU Wei-fa ,CUI Jing ,YUAN Ming, YAO Lu. 2006. Effects of active components from Bacillus mycoides metabolite on immune functions of mice. Veterinary Science in China. 36(12): 983-987.

WANG Gao-xue, BAI Bing, CUI Jing ,LI Xi-han. 2006. Effect of Polysaccharides from Grifola frondosa on Immunological Functions of Crucian Carp Carassius auratus. Fisheries Science. 25(1): 33-37.

WANG Gao-xue ,BAI Bing. 2006. Effect of nine kinds of bacteria and their metabolites on the immune function of Carassius auratus. Journal of Northwest Sci-Tech University of Agriculture and Forestry (Natural Science Edition). 34(2): 39-44.

WANG Gao-xue, YAO Jia-yun, WANG Sui-biao. 2006. Study on Establishment of Water Purification Model of Alga-bacteria System and Its Application in Purifing the Deteriorated Aquacultural Water. Acta Agriculture Boreali-Occidentalis Sinica . 15(2): 786-790.

WANG Gao-xue, Xu Xiang. 2005. Effect of mannatide on immune response of Carassius auratus. Journal of Northwest Sci-Tech University of Agriculture and Forestry (Natural Science Edition). 33(10): 67-70.

Books:

Wang et al., 2005. Hydrobiology, China agriculture press.

Wang et al., 1998. New industrial breeding technique for trionyx sinensis, China agriculture press.

Wang et al., 2002. Collection of efficient breeding technique for courtyard economy animals, China agriculture press.