

Basic Information
Ke Zhang, male, born in 1993, is a Professor and Doctoral Supervisor. He received his Bachelor of Agronomy from the College of Animal Science and Technology, Nanjing Agricultural University in 2015, and his Master of Agronomy from the College of Animal Science and Technology, Northwest A&F University in 2017. In 2022, he earned his Ph.D. in Agronomy from the same institution. From 2022 to 2025, he pursued postdoctoral research at the Mobile Station of Veterinary Science, Northwest A&F University. In July 2025, he was appointed as a Young Professor at Northwest A&F University.
In 2023, he was selected for the Young Talent Support Program of the Shaanxi Association for Science and Technology. He concurrently serves as a Council Member of the Livestock Ecology Branch of the Chinese Association of Animal Science and Veterinary Medicine. In addition, he serves as a Guest Editor for Frontiers in Microbiome and reviews manuscripts for several international journals, including Microbiome, Animal Microbiome, International Journal of Biological Sciences, and BMC Biotechnology.
Research
As a member of the Sheep Genetic Improvement and Biological Breeding Innovation Team, his research focuses on gastrointestinal microbial genomics, host-microbe interactions in ruminants, and the development and efficient utilization of feed probiotics.
Publications
1. Yu Lei *, Yining Zheng *, Yiting Yan *, …, Deng Lu#, Zhipeng Li#, Xiaolong Wang#, Ke Zhang#. Deciphering functional landscapes of rumen microbiota unveils the role of Prevotella bryantii in milk fat synthesis in goats. Genome Biology, 2025 (accepted).
2. Ke Zhang*, Chong He *, Lei Wang *, …, Xiaolong Wang#, Fangqing Zhao# and Yulin Chen#. Compendium of 5810 genomes of sheep and goat gut microbiomes provides new insights into the glycan and mucin utilization. Microbiome. 2024; 12,1 104.
3. Ke Zhang*, Yangbin Xu*, …, Yulin Chen#, Lu Deng# and Yuxin Yang#. Bifidobacterium pseudolongum derived bile acid from dietary carvacrol and thymol supplementation attenuates colitis via cGMP-PKG-mTORC1 pathway. Advanced Science. 2024; 10.1002/advs.202406917.
4. YiTing Yan*, Yu Lei*, Ying Qu, …, Ke Zhang# and Enping Zhang#. Bacteroides uniformis-induced perturbations in colonic microbiota and bile acid levels inhibit TH17 differentiation and ameliorate colitis developments. npj Biofilms Microbiomes. 2023;9(1):56.
5. Ke Zhang*, Ting Zhang*, Mengmeng Guo, …, Yujiang Wu# and Yulin Chen#. Early-life milk replacer feeding mediates lipid metabolism disorders induced by colonic microbiota and bile acid profiles to reduce body weight in goat model. Journal of Animal Science and Biotechnology. 2024;15(1):118.
6. Ke Zhang*, Yangbin Xu*, Yuxin Yang*, …, Daniel Brugger#, Yulin Chen#. Gut microbiota derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model. Animal Nutrition. 2022; 10:111-123.
7. Ke Zhang*, Chong He*, Yangbin Xu, …, Daniel Brugger#, Yujiang Wu#, Yulin Chen#. Taxonomic and functional adaption of the gastrointestinal microbiome of goats kept at high altitude under intensive or extensive rearing conditions. FEMS Microbiology Ecology. 2021 97(3):fiab009.
8. Ke Zhang*, Gongwei Liu*, Yujiang Wu*, …, Xiaolong Wang, Yuxin Yang#, Yulin Chen#. Gut microbial succession patterns and metabolic profiling during pregnancy and lactation in a goat model. Microbiology Spectrum. 2023. 11(1):e0295522.
9. Xi Cao*, Yumeng Fang*, Pingcuo Bandan*, …, De Ji#, Ciren Quzhen#, Ke Zhang#. Age-specific composition of milk microbiota in Tibetan sheep and goats. Applied microbiology and biotechnology. 2024. 108(1):411
10. Mengmeng Guo*, Xi Cao*, De Ji, …, Yulin Chen, Ke Zhang#, Baohua Ma#. Gut microbiota and acylcarnitine metabolites connect the beneficial association between estrogen and lipid metabolism disorders in ovariectomized mice. Microbiology Spectrum. 2023. 11(3):e0014923
Correspondence Address: College of Animal Science and Technology, Northwest A&F University, No. 22 Xinnong Road, Yangling Demonstration Zone, Shaanxi Province
Email: kezhang@nwafu.edu.cn